Publications are organized in different categories

Peer reviewed work from our group:

Khmelinskii, A., Meurer, M., Knop, M. Schiebel, E. (2011) Artificial tethering to nuclear pores promotes partitioning of extrachromosomal DNA during yeast asymmetric cell division. Curr. Biol. 21:R17-18, pdf

Khmelinskii, A., Keller, PJ., Lorenz, H., Schiebel, E. and Knop, M. (2010) Segregation of yeast nuclear pores. Nature, 466:pE1 pdf

Commentaries to the above two papers: 1, 2 (Curr. Biol. Dispatch and Cell Podcast, last 9 minutes)


Keller, PI, Knop, M.
Evolution of mutational robustness in the yeast genome: A link to essential genes and meiotic recombination hotspots
PLoS Genet. 2009, 5:e1000533 pdf

Taxis, C., Stier, G., Spadacchini R., Knop M.
Efficient protein depeletion by genetically encoded deprotection of a dormant N-degron
Mol Sys Biol 2009, 5:267 pdf

Maier P, Rathfelder N, Maeder C. I., Colombelli J., Stelzer E. H. K. and Knop M.
The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis
EMBO J. 2008, 27, 2363-2374. pdf

Maeder C. I., Hink, M., Kinkhabwala, A., Mayr, R., Bastiaens, P. I. H. and Knop, M.
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signaling.
Nat. Cell Biol. 2007, 9, 1319-26. pdf

Maier P., Rathfelder N., Finkbeiner M. G., Taxis C., Mazza M., Le Panse S., Haguenauer-Tsapis R. and Knop M.
Cytokinesis in yeast meiosis depends on the regulated removal of Ssp1p from the prospore membrane
EMBO J 2007 26(7):1843-1852. pdf

Taxis C., Maeder C., Reber S., Rathfelder N., Miura K., Greger K., Stelzer E.H.K. & Knop M.
Dynamic organization of the actin cytoskeleton during meiosis and sporulation in budding yeast
Traffic 2006 Dec;7(12):1628-42. pdf

Gordon O., Taxis C., Keller P.J., Benjak A., Stelzer E.H., Simchen G. & Knop M.
Nud1p, the yeast homolog of Centriolin, regulates spindle pole body inheritance in meiosis.
EMBO J. 2006 Aug 23;25(16):3856-68. pdf

Knop, M.
Evolution of the hemiascomycete yeasts: on life styles and the importance of inbreeding.
Bioessays. 2006 Jul;28(7):696-708. pdf

Taxis, C., Keller, P., Kavagiou, Z., Jensen, L.J., Colombelli, J., Bork, P., Stelzer, E.H.K. & Knop, M.
Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system.
J Cell Biol 2005 Nov 21;171(4):627-40. pdf

Riedel, C.G., Mazza, M., Maier, P., Korner, R. & Knop, M.
Differential requirement for phospholipase D/Spo14 and its novel interactor Sma1 for regulation of exocytotic vesicle fusion in yeast meiosis.
J Biol Chem 2005 Nov 11;280(45):37846-52 pdf

Knop, M., Miller, K.J., Mazza, M., Feng, D., Weber, M., Keranen, S. & Jantti, J.
Molecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast.
Mol Biol Cell 2005 Oct;16(10):4543-56. pdf

Knop, M., Barr, F., Riedel, C.G., Heckel, T. & Reichel, C.
Improved version of the red fluorescent protein (drFP583/DsRed/RFP).
Biotechniques 2002 Sep;33(3):592, 594, 596-8 passim.

Moreno-Borchart, A.C., Strasser, K., Finkbeiner, M.G., Shevchenko, A., Shevchenko, A. & Knop, M.
Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.
EMBO J 2001 Dec 17;20(24):6946-57. pdf

Knop, M. & Strasser, K.
Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis.
EMBO J 2000 Jul 17;19(14):3657-67. pdf

Methods papers (some are peer reviewed):


Kaufmann, A. & Knop, M. (2010) Genomic Promoter replacement cassettes to alter gene expression in the yeast Saccharomyces cerevisiae.
in press

Maeder C. I., Maier P. and Knop M.
A guided tour to PCR-based genomic manipulations of S. cerevisiae (PCR-targeting).
Meth. Microbiol. 2007 36:55-78.

Taxis, C. & Knop, M.
System of centromeric, episomal, and integrative vectors based on drug resistance markers for Saccharomyces cerevisiae.
Biotechniques. 2006 Jan;40(1):73-8. pdf

Janke, C., Magiera, M.M., Rathfelder, N., Taxis, C., Reber, S., Maekawa, H., Moreno-Borchart, A., Doenges, G., Schwob, E., Schiebel, E. & Knop, M.
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes.
Yeast 2004 Aug;21(11):947-62. pdf


Peer reviewed work from collaborations

Di Ventura, B., Funaya, C., Antony, C., Knop, M. & Serrano, L.
Reconstitution of Mdm2-dependent posttranslational modifications of p53 in yeast
PLoS ONE 2008; 3(1) e1507. pdf

Reynaud, E.G., Andrade, M.A., Bonneau, F., Ly, T.B., Knop, M., Scheffzek, K. & Pepperkok, R.
Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization.
BMC Biol. 2005 Oct 7;3:21. pdf

Maekawa, H., Usui, T., Knop, M. & Schiebel, E.
Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions.
EMBO J 2003 Feb 3;22(3):438-49. pdf

Rabitsch, K.P., Toth, A., Galova, M., Schleiffer, A., Schaffner, G., Aigner, E., Rupp, C., Penkner, A.M., Moreno-Borchart, A.C., Primig, M., Esposito, R.E., Klein, F., Knop, M. & Nasmyth, K.
A screen for genes required for meiosis and spore formation based on whole-genome expression.
Curr Biol 2001 Jul 10;11(13):1001-9. pdf


Reviews and commentaries


Taxis, C. & Knop, M.
Regulation of exocytotic events by centrosome-analogous structures.
Topics Curr. Gen. 2004 10 193-207

Moreno-Borchart, A.C. & Knop, M.
Prospore membrane formation: how budding yeast gets shaped in meiosis.
This is a review article.
Microbiol Res 2003;158(2):83-90.

Lacefield, S., Ingolia, N.
Signal transduction: External signals influence spore-number control
Curr Biol 2006 16 (4): R125-R127 pdf



Publications from before

Pereira, G., Grueneberg, U., Knop, M. & Schiebel, E.
Interaction of the yeast gamma-tubulin complex-binding protein Spc72p with Kar1p is essential for microtubule function during karyogamy.
EMBO J 1999 Aug 2;18(15):4180-95.

Knop, M., Siegers, K., Pereira, G., Zachariae, W., Winsor, B., Nasmyth, K. & Schiebel, E.
Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines.
Yeast 1999 Jul;15(10B):963-72.

Elliott, S., Knop, M., Schlenstedt, G. & Schiebel, E.
Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication.
Proc Natl Acad Sci U S A 1999 May 25;96(11):6205-10.

Knop, M., Pereira, G. & Schiebel, E.
Microtubule organization by the budding yeast spindle pole body.
This is a review article.
Biol Cell 1999 May-Jun;91(4-5):291-304.

Knop, M. & Schiebel, E.
Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation.
EMBO J 1998 Jul 15;17(14):3952-67.

Pereira, G., Knop, M. & Schiebel, E.
Spc98p directs the yeast gamma-tubulin complex into the nucleus and is subject to cell cycle-dependent phosphorylation on the nuclear side of the spindle pole body.
Mol Biol Cell 1998 Apr;9(4):775-93.

Knop, M. & Schiebel, E.
Spc98p and Spc97p of the yeast gamma-tubulin complex mediate binding to the spindle pole body via their interaction with Spc110p.
EMBO J 1997 Dec 1;16(23):6985-95.

Knop, M., Pereira, G., Geissler, S., Grein, K. & Schiebel, E.
The spindle pole body component Spc97p interacts with the gamma-tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplication.
EMBO J 1997 Apr 1;16(7):1550-64.

Knop, M., Hauser, N. & Wolf, D.H.
N-Glycosylation affects endoplasmic reticulum degradation of a mutated derivative of carboxypeptidase yscY in yeast.
Yeast 1996 Sep 30;12(12):1229-38.

Geissler, S., Pereira, G., Spang, A., Knop, M., Soues, S., Kilmartin, J. & Schiebel, E.
The spindle pole body component Spc98p interacts with the gamma-tubulin-like Tub4p of Saccharomyces cerevisiae at the sites of microtubule attachment.
EMBO J 1996 Aug 1;15(15):3899-911.

Knop, M., Finger, A., Braun, T., Hellmuth, K. & Wolf, D.H.
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast.
EMBO J 1996 Feb 15;15(4):753-63.

Finger, A., Knop, M. & Wolf, D.H.
Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast.
Eur J Biochem 1993 Dec 1;218(2):565-74.

Knop, M., Schiffer, H.H., Rupp, S. & Wolf, D.H.
Vacuolar/lysosomal proteolysis: proteases, substrates, mechanisms.
This is a review article.
Curr Opin Cell Biol 1993 Dec;5(6):990-6.