Members' Directory

Biography: My group is currently working on tumor-stroma interactions, both on RNA (gene expression) and protein (2D, mass spectrometry) level.

Biography: 1986- : ingénieur électronicien at CNRS France

Biography: - Texas Instruments Inc., Dallas, USA, 1969 - 1973
- CERN GENEVA, Switzerland, 1973 - 1978
- EMBL Heidelberg, Germany, 1979 - 2005
- EPFL (ETH Lausanne), Switzerland, 2005 -

Biography: Education:
1986 Doctoral Degree in Biological Sciences, summa cum laude, University of Naples ??Federico II?, Italy

Scientific and academic career:
1983-1986 Pre-doctoral fellow, Dept. of Organic and Biological Chemistry, University of Naples ?Federico II?, Italy
1987 Visiting fellow, European Laboratory for Molecular Biology (EMBL), Heidelberg
1988-1990 Post-doctoral fellow from Italian Association for Cancer Research, Dept. of Biochemistry and Medical Biotechnology, University of Naples ?Federico II?, Italy
1991-1992 Scientific consultant for Genetic Engineering Center, Dept. of Biochemistry and Medical Biotechnology, University of Naples ?Federico II?, Italy
1993-2005 Research Associate of Biochemistry, School of Pharmacy, University of Catanzaro ?Magna Graecia?, Italy
2005-onward Associate Professor of Biochemistry, School of Pharmacy, University of Catanzaro ?Magna Graecia?, Italy

Main research fields:
1983-1986 Studies on the primary structure of protamine from Chaetopterus variopedatus
1987-1990 Identification of promoter regions responsible for acute phase induction of the C-reactive protein gene; regulation by IL-1 and IL-6
1991-1992 Production in Escherichia coli and structure-function studies of IL-6 and Lipocortin-1
1993-1997 Thrombin engineering: production of mutants with altered enzymatic activity and studies on mitogenic activity
1998-2002 Thrombin-serpin complex: production of ATIII and protease Nexin1 (PN1); biochemical interactions with thrombin mutants. Role of thrombin-serpin balance in cell proliferation and differentiation
2003 Studies on selective inhibitory activity of tacrine-like molecules (paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterase
2004-onward Studies on antitumor effects of IL-6 receptor super-antagonist Sant7 in vitro model of human myeloma

Biography: I did my PhD at EMBL from 1986-1989 and returned to join the protein and peptide group from 1995-2000.

Biography: After leaving EMBL I worked at UCLA for 3 years and took an additional training program at Woods Hole Cell Physiology Course. In 1993 I left UCLA to take a faculty position in the Department of Medicine at Northwestern Medical School. In 1996 I moved to Indiana University Medical School where I am a faculty in the Division of Nephrology. We have been working to extend the utility of light microscopy methods by using multiphoton imaging to image into live animals.

Biography: Patrick Baeuerle has served as Micromet's Chief Scientific Officer since October 1998. From February 1996 to September 1998, Patrick headed the drug discovery activities of Tularik, Inc., in South San Francisco, California, as Director, Drug Discovery. From October 1994 to February 1996, he served as a full Professor and Chairman of Biochemistry at the Medical Faculty of Freiburg University, Germany. In 1989, Patrick was awarded a group leader position at the Gene Center in Martinsried, Germany, where he did research on transcription factor NF-kappaB. According to a survey by the Institute for Scientific Information (ISI, Philadelphia, PA, USA), he was Germany's most frequently cited biomedical scientist of the past decade, and 38th worldwide. He has published more than 200 scientific papers, and four educational children books on biology. Patrick was appointed Honorary Professor of Immunology at the University of Munich in 2000. He performed his Ph.D. work at the Max Planck Institute for Psychiatry in Martinsried and at the European Molecular Biology Laboratory (EMBL) in Heidelberg, obtained a Ph.D. degree in biology from the University of Munich, and performed his post-doctoral research with David Baltimore at the Whitehead Institute of the Massachusetts Institute of Technology, Cambridge, MA.