Members' Directory

Biography: July 2011 - July 2012 postdoc University of California San Francisco (UCSF)
Aug 2010 - Dec 2010 postdoc University of Edinburgh, UK
Oct 2008 - July 2010 postdoc EMBL-Monterotondo, Italy
Feb 2004 - Sept 2008 predoc EMBL-Monterotondo, Italy
Oct 2000 - June 2001 University of Glasgow, UK
Oct 1998 - Jan 2004 University of Vienna, Austria

Biography: BSc. degree: 1975- 1978, 1st Class Honors, Reading University, UK

PhD. Thesis: 1978-1981 , "The interferon system in the developing mouse embryo" Warwick University, UK. Supervisor: Prof. DC Burke

Post-Doctoral Fellowship (1) 1981-1985 with Dr. Brigid Hogan, at the I.C.R.F. Mill Hill Laboratories, London, U.K. Project - Isolation of basement membrane genes

Post-Doctoral Fellowship (2) 1985-1988 with Dr. Hans Lehrach, at the E.M.B.L. Heidelberg, Germany. Project - Molecular strategies to isolate developmental genes from the mouse t complex region.

Group Leader (1) 1988-1995 Institute of Molecular Pathology (I.M.P), Vienna.
Research area: Mammalian Developmental Genetics, focus on genomic imprinting. (5 + 3 year position). Elected EMBO member in 1995

Group leader (2) 1996 ? 2001 (May) The Netherlands Cancer Institute, Amsterdam, The Netherlands, Research area: links between mammalian development and tumor genetics (Permanent position)

Head, Department of Developmental Genetics, Austrian Academy of Sciences, Institute of Molecular Biology, Salzburg, Austria. From 1st June 2000 (Permanent position)

General scientific interest:
1. Mammalian development in mice and the involvement of developmental genes in human disease. The last 10 years, focus on genomic imprinting function and mechanism. We earlier identified the mouse Igf2r gene as an imprinted gene also demonstrated that this gene uses a methylation imprint to express the maternal allele. Many imprinted genes now appear to carry methylation imprints that act to express the active allele. Silencing of the paternal Igf2r allele was recently shown to involve a regulatory non-coding RNA named Air . Future work will investigate the mechanism of silencing by non-coding RNAs and their general application to silencing imprinted genes. July 25, 2002.
2. Member and current chair of the EMBO Science and Society Committee

Biography: studies at the Ruprecht Karls University in Heidelberg (10/1995 - 01/2000)
Diploma Thesis with Dirk Bohmann at EMBL Heidelberg and University of Rochester, USA (02/2000 - 06/2001): AP1 interacting proteins in Drosophila
PhD thesis with Stephen Cohen at EMBL Heidelberg (08/2001 - 07/2004): the role of the bantam microRNA during Drosophila development and identification of microRNA targets
bridging postdoc with Stephen Cohen at EMBL Heidelberg (03/2005 - 01/2006): microRNA targets in Drosophila
postdoctoral studies with Gregory Hannon at Cold Spring HArbor Laboratories 03/2006 - 12/2008: The piRNA pathway and its role in silencing selfish genetic elements in the Drosophila germline
since 01/2009: groupleader at the IMBA in Vienna Austria

Biography: Univ. Vienna, A
IMP, Vienna, A
Univ. Salzburg, A
EMBL 1993 - 1997 in Group of Chris Sander (Biocomputing)
EMBO fellow and Staff Scientist at EMBL / EBI
Founder and VP at LION Bioscience AG 1997 - 2002
VP Informatics at Cellzome 2002-2005
Oridis biomed, Graz, A 2005-2009
CeMM, Research Center for Molecular Medicine, Vienna, A 2009-

Biography: Education

Period: 1981-1986
Study: Chemistry
University of Ljubljana, Slovenia
Degree: Engineer of chemistry
Year: 1986
Subject: IR spectroscopy on hydrogen malonates


Period: 1986-1989
Study: Master in chemistry
University of Ljubljana, Slovenia
Year: 1989
Degree: Master of chemistry
Subject: X-ray structure analysis of hydrogen malonates


Period: 1989-1992
Study: PhD in chemistry
University of Pavia, Italy and University of Ljubljana, Slovenia
Degree: Doctor of chemical sciences

Scientific positions

Period: 1986 - 1991
Position: Research Assistant
University of Ljubljana, Dept. of Chemistry, Ljubljana, SLO

Period: 1989 - 1991
Financed: AREA Research Park, Trieste, Italy
Position: Study leave in:
University of Pavia, Dept. Genetics and Microbiology, Pavia, I


Period: 1991 - 1992
Position: Lecturer
University of Ljubljana, Dept. of Chemistry, Ljubljana, SLO


Period: 1992 - 1995
Financed: Pharmacia/Farmitalia fellowship
Position: Post-doctoral research associate
University of Pavia, Dept. Genetics and Microbiology, Pavia, I

Period: 1995 - 1997
Financed: EMBO fellowship and EMBL post-doctoral fellowship
Position: Post-doctoral research fellow
EMBL-Heidelberg, Heidelberg, Struct. Biol. Program, D

Period: 1997 - 1999
Position: Staff Scientist
EMBL-Heidelberg, Heidelberg, Struct. Biol. Program

Period: September 1999 - August 2004
Sincrotrone Trieste, Struct. Biol. Lab., Trieste, I
Position: Head of Structural Biology and Crystallography Unit


Period: September 2004 -
University of Vienna
Max F. Perutz Laboratories

Position: Professor of Molecular Structural Biology and Head of the Department for Structural and Computational Biology

Biography: 1999 - Professor of Genetics, University of Salzburg
1987- 1999 Head of the Molecular Analysis of Mammalian Mutation Laboratory, Imperial Cancer Research Fund, London
1978-1987 Joint group leader at the EMBL