Members' Directory

Biography: Born in Naples (Italy) 09/04/69
Degree in Farmaceutical Chemistry-Univ.of Naples (Italy) 1992
PhD in Biochemistry and Biophisics-Univ. of Padua (italy) 1998
Post doc in Structural Biology-Univ. of Parma (Italy) 1998-2002
Post doc at Molecular Structure Division-NIMR London (UK) 2002-2005
Senior Investigator Scientist (Permanent position) at NIMR since February 2005

Biography: -01/10/2003-31/09/2004: visiting worker at MRC, Mill Hill, London (UK)
-01/01/1998-present: University of Parma (Parma, Italy), research associate, Sructural Biology
-01/11/1997-31/12/1997: Division of Structural Biology NMR Laboratory Pharmacia & Upjohn (Milan, Italy), fellowship, Structural Biology (Dr. G. Bolis)
-01/11/1994-31/10/1997: University of Genoa (Genoa, Italy), PhD student, Biophysics (Prof. C. Nicolini)
-01/04/1994-31/10/1994: Division of Structural Biology NMR Laboratory Pharmacia & Upjohn (Milan, Italy), fellowship, Structural Biology (Dr. G. Bolis)
-01/11/1992-31/03/1994: University of Genoa (Genoa, Italy), fellowship, Biophysics (Prof. C. Nicolini)
-01/03/1992-31/10/1992: University of Florence (Florence, Italy), fellowship postgraduate, Chemistry (Prof. I. Bertini)
-01/08/1990-01/03/1992: University of Florence (Florence, Italy), student-experimental thesis, Chemistry (Prof. I. Bertini)
-01/08/1989-31/07/1990: National Health Service (Pisa, Italy), civil service
-01/10/1983-01/03/1992: University of Florence (Florence, Italy), student, Chemistry

Biography: Piero Andrea Temussi

27 July 1939 Born in Nuoro, Sardinia, Italy
1962 Laurea, ?summa cum laude?, in Chemistry, University of Naples, Italy
1966 Postdoc with Prof. Herb Gutowsky, University of Illinois, Urbana, USA
1967 Visiting scientist with Prof. Shneior Lifson at Weizmann Institute, Rehovot, Israel
1968-1980 Assistant professor, University of Naples, Italy
1980-present Full professor, University of Naples, Italy
1984 Visiting professor at UCSD, La Jolla, CA, USA
1991 Visiting professor at Protein Institute, University of Osaka, Japan
2002 Visiting scientist at EMBL, Heidelberg, Germany
2002-present Visiting scientist at NIMR, MRC, Mill Hill, London, UK
2003-2005 Member of Interdisciplinary Centre, Accademia dei Lincei, Rome, Italy
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Recent publications

Nair M, Adinolfi S, Pastore C, Kelly G, Temussi P, Pastore A. (2004) Solution Structure of the Bacterial Frataxin Ortholog, CyaY: Mapping the Iron Binding Sites. Structure (Camb). 12, 2037-48.

Tancredi T, Pastore A, Salvadori S, Esposito V, Temussi PA. (2004) Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin. Eur J Biochem. 271, 2231-40.

Bolis D, Politou AS, Kelly G, Pastore A, Temussi PA (2004) Protein stability in nanocages: a novel approach for influencing protein stability by molecular confinement. J Mol Biol. 336, 203-12.

Temussi PA, Masino L, Pastore A. (2003) From Alzheimer to Huntington: why is a structural understanding so difficult? EMBO J. 22, 355-61.

Temussi PA. Why are sweet proteins sweet? Interaction of brazzein, monellin and thaumatin with the T1R2-T1R3 receptor. (2002) FEBS Lett. 526, 1-4.

Biography: Julie Thompson is a research scientist at the Institute of Genetics and Molecular and Cellular Biology (IGBMC) in Strasbourg, France. She received her B.Sc. (Hons) in Mathematics at Sheffield University in England and her PhD. in bioinformatics from Strasbourg University in France. After a number of years as a computer scientist in industry, she joined the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany where she first studied multiple sequence alignment algorithms and developed the program ClustalW/X in collaboration with the original authors. In 1995, she joined the IGBMC, where she continued her research on multiple sequence alignment construction and analysis algorithms. Her recent work has focused on problems of data standardization and program interoperability in the increasing complex field of evolutionary informatics and evolutionary systems biology.