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  • Hoflack Group
 
About 8 results

  1. Agustin Alconada

    Current information Patent attorney, ABG Patentes S.L. Avenida de Burgos 16D Madrid, Spain E-mail Nationality: Spanish
    EMBL information Postdoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1994 to 1997

  2. Ben Distel

    Current information Associate Professor, University of Amsterdam Academic Medical Center, K1-259
    Department of Medical Biochemistry
    Meibergdreef 15     Amsterdam, Netherlands E-mail Nationality: Dutch
    EMBL information Visitor Hoflack Group Cell Biology and Biophysics From 1993 to 1994

  3. Bernard Hoflack

    Current information Professor, Technical University of Dresden BIOTEC,
    BioInnovationsZentrum
    Tatzberg 47-51     Dresden, Germany E-mail Nationality: French
    EMBL information Group Leader Hoflack Group Cell Biology and Biophysics From 1987 to 1996 Biography Hide biography
    Biography: 1982: PhD, University of Sciences, Lille, France
    1984-1985: Post-doctoral training at Washington University, St-Louis, USA
    1986-1987: Research scientist, Centre National de la Recherche Scientifique, Lille
    1988-1996: Group Leader, at EMBL, Heidelberg
    1997-2001: CNRS Research Director at the Institut de Biologie de Lille, Lille, France
    2002-present: Professor of Proteomics at TU-Dresden

  4. Roland Le Borgne

    Current information Group Leader, Institut de Génétique et du Développement CNRS UMR 6061
    Université de Rennes 1-Faculté de Médecine
    2 avenue du Pr L. Bernard
    CS 34 317     Rennes, France E-mail Nationality: French
    EMBL information Predoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1992 to 1996 Research interests: Asymmetric cell division, cell polarity, membrane trafficking, developmental cell biology, Drosophila, , summary: Cell-cell signaling is a central process in the formation of multicellular organisms. Work in my lab aims at understanding the role of membrane trafficking during cell-cell signaling within polarized epithelial cells. In particular, we are studying the regulation of Notch receptor signaling using a combination of fly genetics and cutting-edge cell biology methodologies , , Biography Hide biography
    Biography: Since 2006 - Group leader, ATIP Biologie du Développement, CNRS UMR 6061_
    1999-2005 - Researcher, Ecole Normale Supérieure, CNRS UMR 8542_
    1996-1998 - Post-doctoral fellow, Institut de Biologie de Lille _
    1992-1995 - PhD Cell biology department, EMBL_1992 - DEA Biologie Santé, Université de Montpellier

    Selected Publications
    1 - Smith C.A., Lau K.M., Rahmani Z., Dho S.E., Brothers G., She Y.M., Berry D.M., McGill M.A., Bonneil E., Thibault P., Schweisguth F., Le Borgne R. and McGlade C.J. aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb. (2007) EMBO J., jan 4, ahead publication
    2 - Le Borgne, R. (2006). Regulation of Notch signalling by endocytosis and endosomal sorting. Curr. Opin. Cell Biol. 18(2), 213-22.__
    3 - Langevin,L., Le Borgne, R., (equal contribution), Rosenfeld, F., Gho,M., Schweisguth, F. and Bellaïche, Y. (2005). Lethal giant larvae controls the localisation of the Notch signalling regulators Numb, Neuralized and Sanpodo in Drosophila sensory organ precursor cells. Curr. Biol. 15, 955-62.__
    4- Le Borgne, R., Bardin, A. and Schweisguth F. (2005) Roles of receptor and ligand endocytosis in the regulation of Notch signaling. Development 132, 1751-62.__
    5 - Le Borgne, R., Remaud, S., Hamel,S., and Schweisguth F (2005). The E3 ubiquitin ligases Mind bomb and Neuralized have distinct and complementary functions in the regulation of Delta and Serrate activity in drosophila. PLoS Biology 3, e96.__
    7 - Le Borgne, R. and Schweisguth, F. (2003). Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev. Cell 5(1), 139-148.__
    8 - Le Borgne, R. and Schweisguth, F. (2003). Notch signaling: endocytosis makes Delta signal better. Curr. Biol. 23, R273-R275.__
    10 - Le Borgne, R., Bellaïche, Y. and Schweisguth, F.(2002) ,Curr. Biol. 12, 95-104.

  5. Fabienne Mauxion

    Current information CNRS position, CGM-CNRS UPR2167 CGM
    Batiment 24
    Avenue de la terrasse     Gif-sur-Yvette Cedex, France E-mail Nationality: French
    EMBL information Postdoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1991 to 1996

  6. Hélène Munier-Lehmann

    Current information permanent position at INSERM, Pasteur Institute Paris Institut Pasteur
    Unité de Chimie et Biocatalyse
    28 Rue du Dr Roux     Paris cedex 15, France E-mail Nationality: French
    EMBL information Postdoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1993 to 1996

  7. Stéphane Méresse

    Current information Chargé de Recherche CNRS, INSERM-CNRS Centre d'Immunologie de Marseille Luminy Case 906, Parc Scientifique de Luminy Marseille Cedex 9, France E-mail Nationality: French
    EMBL information Postdoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1989 to 1992

  8. Anne Schmidt

    Current information Group Leader, Institut Jacques Moniod, CNRS Universites Paris VI et VII,
    2 place Jussieu
    Tour 43
    aile 43-44,
    5eme etage     Paris Cedex 05, France E-mail Nationality: French
    EMBL information Postdoctoral Fellow Hoflack Group Cell Biology and Biophysics From 1991 to 1993 Biography Hide biography
    Biography: Anne Schmidt
    PhD in Cellular and Molecular Biology obtained at the University of Montpellier (march 1991).
    Post-doctoral position at EMBL in the Cell Biology Department (EMBO Fellow, march 1991- may 1993).
    Post-doctoral position at the University of Heidelberg, Department of Neurobiology (SFB and MPI post-doctoral positions).
    Current status: Group leader at the CNRS (French National Center for Scientific Research), research group ?Role of lipid modifications in membrane dynamics?.
    Area of research: We are currently trying to unravel the molecular mechanisms that underlie the function of lipid-binding and lipid-modifying proteins in membrane deformations. More precisely, our interest is focused on a family of proteins referred to as endophilins that are involved in vesicle budding from diverse intracellular compartments. We are working on a key functional aspect of these proteins, i.e. their intrinsic acyl-transferase activity and are trying to understand the role of this enzymatic property in vesicle budding and fission.