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- Wade Group
Bedamati DasCurrent information Postdoc, Florida State University Supercomputer Computation Research Institute (SCRI)
School of Computational Science
400 Dirac Science Library Tallahassee, USA E-mail Nationality: IndianEMBL information Postdoctoral Fellow Wade Group Structural and Computational Biology From 04.1996 to 11.1997
Eugene DemchukCurrent information Associate Professor, West Virignia University Robert C. Byrd Health Sciences Center
Computational Toxicology Laboratory
Division of Toxicology and Environmental Medicine
1600 Clifton Road Atlanta, USA E-mail Nationality: RussianEMBL information Postdoctoral Fellow Wade Group Structural and Computational Biology From 1992 to 1994
Volkhard HelmsCurrent information Professor, Saarland University Center for Bioinformatics
Postfach 15 11 50 Saarbrücken, Germany E-mail Nationality: GermanEMBL information Predoctoral Fellow Wade Group Structural and Computational Biology From 1992 to 1996
Current information Head of R&D, Scientist, KKS Ultraschall AG Frauholzring 29 Steinen, Switzerland E-mail Nationality: GermanEMBL information Staff Scientist Wade Group Structural and Computational Biology From 1994 to 1996 Biography Hide biographyBiography: study: Chemistry, Humboldt University Berlin
PhD: in Theoretical Chemistry, Academy of Sciences, Berlin
Habilitation: Physical Biochemistry, University Potsdam
Privat lecturer: in Physical Biochemistry, University of Potsdam
Research group leader in fundamental research
Research fields: Protein dynamics, FTIR, Thiolate heme proteins (Cytochrome P450, NO synthase); Head of Research and Development in Surface Technology, Titanium implants
Current information Patent Examiner, European Patent Office Erhardtstrasse 27 Munich, Germany Nationality: ItalianEMBL information Postdoctoral Fellow Wade Group Structural and Computational Biology From 1996 to 1999
Sanja TomicCurrent information Research associate, Institute Rudjer Boskovic (Physical Chem. dep.) Bijenicka 54
P.O.Box 180 Zagreb, Croatia E-mail Nationality: CroatianEMBL information Postdoctoral Fellow Wade Group Structural and Computational Biology From 1996 to 1998
Current information Professor, Heidelberg Institute for Theoretical Studies (HITS) Schloss-Wolfsbrunnenweg 35 Heidelberg, Germany E-mail Nationality: BritishEMBL information Group Leader Wade Group Structural and Computational Biology From 1992 to 2005 Research interests: Computational structural biology, molecular modeling and simulation, structure-based drug design, protein engineering, structural systems biology Biography Hide biographyBiography: 1985 B.A. Hons. in Physics, 1988 D. Phil. in Molecular Biophysics, University of Oxford, UK.
1988-91: Postdoc at Universities of Houston and Illinois, USA
1992-2001: Group Leader, 'Molecular Modeling, Simulation and Design', EMBL, Heidelberg
2001- present: Group Leader, Molecular and Cellular Modeling Group, HITS (formerly EML Research).
2012- present: Professor, Center for Molecular Biology (ZMBH), Heidelberg University
Current information Group Leader, University of Birmingham Centre for Systems Biology
School of Biosciences
The University of Birmingham
Edgbaston Birmingham, United Kingdom E-mail Nationality: BritishEMBL information Postdoctoral Fellow Wade Group Structural and Computational Biology From 11.1999 to 01.2005 Research interests: Protein conformation, protonation states and function; Prediction of protein interactions; Understanding how higher protein organization leads to specific functionality; Fast predictions of protein flexibility and conformation; Discovery of small molecule inhibitors. Ubiquitination Biography Hide biographyBiography: Selected Publications
P. J. Winn, S. K. Luedemann, R. Gauges, V. Lounnas and R. C. Wade. Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a new functional role for a buried arginine. PNAS (USA), 2002, 99(8), 5361-5366.
P. J. Winn, T. L. Religa, J. N. D. Battey, A. Banerjee, R. C. Wade. A comparative analysis of the interaction properties of the E2 ubiquitin conjugating enzymes and related proteins. Structure, 2004, 12(9), 1563-74
K. Schleinkofer, Sudarko, P. J. Winn, S. K. Luedemann, R. C. Wade. Do mammalian cytochrome P450s exhibit multiple ligand access pathways and ligand channelling? EMBO Reports, 2005, 6(6), 584-589.
P. J. Winn, M. Zahran, J. N. Battey, Y. Zhou, R. C. Wade. A. Banerjee, Structural and electrostatic Properties of Ubiquitination and Related Pathways. Frontiers in Bioscience, 2007, 12, 3419-3430.
V. Cojocaru, P. J. Winn, R. C. Wade. The Ins and Outs of Cytochrome P450s, Biochim. Biophys. Acta, 2007, 1770(3), 390-401.