Members' Directory

Biography: 2013-Present Directeur de Recherche, DR1 CNRS, IGBMC/ Strasbourg
2003-2012 Team Leader, EMBL, Heidelberg (Germany)
1994 Directeur de Recherche, DR2 , CNRS, Paris
1984 State Doctorat at Université of Paris VI, Natural Sciences
1980 Researcher position in CNRS (permanent position)
1979-80 Université of Paris VI Doctorat de 3ème cycle, Biology

Biography: PLACE AND DATE OF BIRTHDAY: Napoli (Italy) - November 19, 1957
CITIZENSHIP: Italian

EDUCATION
Degree in Biology. University "Federico II", Naples, Italy.
PhD in Cellular Biology, University of Pavia, Italy.

POSITIONS HELD
- From June 2002. Assistant Professor of Molecular Biology, Department of Structural and Functional Biology, University "Federico II", Naples, Italy.
- January 1996 - May 2002. Research Associate. Dept. of Public Health – Parasitology Unit, University "La Sapienza", Rome, Italy. Prof. M. Coluzzi group. (From July 1999 to June 2000 at EMBL).
- 1990 -1995. IMBB- and EU-Postdoctoral fellow. Insect Molecular Genetics Group, Institute of Molecular Biology & Biotechnology (Heraklion, Crete, Greece). Supervisor: Prof. C. Savakis.
- 1989 -1990. CNR fellow. CNR Institute of Cybernetics, Arco Felice (Naples, Italy). Dr. L. De Petrocellis laboratory.
- 1986 -1989. Post-degree training. Department of Genetics, General and Molecular Biology (DGBM), University "Federico II", Naples, Italy. Prof. Laura Fucci laboratory.

SCIENTIFIC INTERESTS
Molecular biology studies on the malaria vector Anopheles gambiae with special emphasis on the salivary glands, transgenesis and host-parasite interactions. Transposable elements.

Biography: Education:
1986 Doctoral Degree in Biological Sciences, summa cum laude, University of Naples ??Federico II?, Italy

Scientific and academic career:
1983-1986 Pre-doctoral fellow, Dept. of Organic and Biological Chemistry, University of Naples ?Federico II?, Italy
1987 Visiting fellow, European Laboratory for Molecular Biology (EMBL), Heidelberg
1988-1990 Post-doctoral fellow from Italian Association for Cancer Research, Dept. of Biochemistry and Medical Biotechnology, University of Naples ?Federico II?, Italy
1991-1992 Scientific consultant for Genetic Engineering Center, Dept. of Biochemistry and Medical Biotechnology, University of Naples ?Federico II?, Italy
1993-2005 Research Associate of Biochemistry, School of Pharmacy, University of Catanzaro ?Magna Graecia?, Italy
2005-onward Associate Professor of Biochemistry, School of Pharmacy, University of Catanzaro ?Magna Graecia?, Italy

Main research fields:
1983-1986 Studies on the primary structure of protamine from Chaetopterus variopedatus
1987-1990 Identification of promoter regions responsible for acute phase induction of the C-reactive protein gene; regulation by IL-1 and IL-6
1991-1992 Production in Escherichia coli and structure-function studies of IL-6 and Lipocortin-1
1993-1997 Thrombin engineering: production of mutants with altered enzymatic activity and studies on mitogenic activity
1998-2002 Thrombin-serpin complex: production of ATIII and protease Nexin1 (PN1); biochemical interactions with thrombin mutants. Role of thrombin-serpin balance in cell proliferation and differentiation
2003 Studies on selective inhibitory activity of tacrine-like molecules (paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterase
2004-onward Studies on antitumor effects of IL-6 receptor super-antagonist Sant7 in vitro model of human myeloma

Biography: I graduated in Biology and Bioinformatics at Bordeaux University, France. I came to the EBI, within the sequence database group, to work on orthologues prediction.
Subsequently, I worked at the Welcome Trust Sanger institute on copy number variation in human.
I did my PhD at Lausanne University, in Victor Jongeenel's and Sven Bergmann's labs working on methods to infer copy number variation from normal and cancer genomes.
I am currently working at the Nestlé Institute of Health Sciences. My research focuses on nutrigenomics studies and on the potential impact of personalized nutrition on metabolic disease.

Biography: 2001/2002 Diploma thesis "Develepment of the Cerebral Cortex", Prof. Peter Gruss
2002 Diploma at the University of Göttingen
2002-2006 Ph.D. at the MPI International Research School "Structure and Function of Biological Membranes" in Frankfurt working on "Glycine Transporter 2 in the Nervous System"
2006-present Postdoctoral Fellow at the Children's Hospital in Boston, USA working on "functional aspects of the glutamate transporter GLT1"

Biography: 1994-1998 : PhD Thesis at the Grenoble University in the Laboratory of Structural Electron Microscopy - Director : Dr R. H. Wade - Study of Microtubule/Kinesins Complexes
1998-2001 : Post-Doc at EMBL in the Group of Drs A. Hyman and E. Karsenti - Study of Microtubule Dynamics and Structure -

Biography: Studies: chemistry, universities Vienna and Freiburg;
PhD 1975 Max-Planck-Institut for Immunobiology, Freiburg
Postdoc: WEHI,Melbourne; Centre d'Immunologie,Marseille

Staff position since 1980 at the German Cancer Research Center

Research topic: immunological tolerance and autoaggression using genetically modified mice.

Biography: Frederico Gonzalez Colombo Arnoldi has bachelor degree in Biological Sciences (2004) and PhD in Molecular and Cell Biology (2009) from São Paulo State University, Brazil, with a period at the National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Japan. He was professor at Sorocaba University (2008-2009), teaching Industrial Biotechnology, Biochemistry, Genetic Engineering and Nanotechnology. Since the second semester of 2009, he is post-doc researcher at Ribeirão Preto School of Medicine in the field of Bioinformatics for Tuberculosis, with an internship at the European Molecular Biology Laboratory (EMBL - Heidelberg, Germany). He can work in the fields of Bioinformatics, Biotechnology and Molecular Biology. On the bench, he already worked with mouse models, cell culture (mammals and bacterial cells), cloning, sequencing and expression of proteins and with flow cytometry; about in silico methods, he already worked with alignment of gene sequences, phylogenetical analysis, assembly and annotation of mitochondrial genomes, protein homology modelling, microarray data analysis and text-mining. He has knowledge on Statistics, including multivariate analysis, computer programming (Python and R), and Artificial Intelligence. Papers in which he participated as author or coauthor can be found at PubMed using the query "Arnoldi F.G.[au] or Arnoldi F.C.[au]" or by looking for Scopus Author ID 8732317700.