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Grenoble, 12 December 2010 How cells export and embed proteins in the membrane Scientists at EMBL Grenoble were the first to determine the structure of a ribosome-protein complex involved in carrying nascent proteins out of the cell. Their work, published today in Nature Structural and Molecular Biology, could increase understanding of illnesses such as cystic fibrosis and some forms of Parkinson’s disease.
Heidelberg, 2 December 2010 Better imaging from bench to bedside Euro-BioImaging, a project which launches its preparatory phase today, aims to provide scientists throughout Europe with open access to state-of-the-art imaging technologies at all levels of biological and biomedical research, from bench to bedside.
Grenoble, 16 November 2010 One-touch make-up - for our cells A new technique developed by scientists at EMBL Grenoble and collaborators enables them to introduce up to 15 fluorescent markers to a mammalian cell in one go, and could help speed up drug development and screening.
Heidelberg/Hinxton, 27 October 2010 1000 Genomes Project ushers in new era for human genetics Researchers at EMBL-EBI and colleagues around the world have completed the pilot phase of the 1000 Genomes Project, a major international collaboration to build a detailed map of human genetic variation. Published today in Nature, the study provides valuable insights into the nature of human genetic variation and will underpin the next phase of human genetic research.
Heidelberg, 2 September 2010 Brainy worms: Evolution of the cerebral cortex Unexpectedly, scientists at EMBL Heidelberg have now discovered a true counterpart of the cerebral cortex in an invertebrate, a marine worm. Their findings, published today in Cell, give an idea of what the most ancient higher brain centres looked like, and what our distant ancestors used them for.
- Discover Magazine (USA) , 16 December 2010 'Top 100 Stories of 2010: #12'
- Frankfurter Allgemeine Zeitung (Germany) , 10 September 2010 ‘Als Intelligenz in Röhren durch die Welt wanderte’
- Deutshlandfunk radio (Germany) , 6 September 2010 ‘Was ist im Wurm drin?’
- Scientific American online (USA) , 2 September 2010 ‘Worms for brains: Can genes point the way to the cerebral cortex's common ancestor with marine annelids?’
- Spektrum der Wissenschaft (Germany) , 2 September 2010 ‘Der Ringelwurm - Verwandter aller Intellektuellen’
- Scinexx (Germany) , 3 September 2010 ‘Meereswurm mit „Köpfchen“’
- Discovery Channel online news (USA) , 2 September 2010 ‘Human-Like Brain Found in Worm’
- BBC online (UK) , 2 September 2010 ‘Worm gene maps give clue to higher brain evolution’
- The Loom – Discover Magazine blogs (USA) , 3 September 2010 ‘The Worm In Your Brain’
Monterotondo, 25 August 2010 Freeze or run? Not that simple Scientists at EMBL Monterotondo and GlaxoSmithKline in Verona, Italy, have identified the specific type of neurons that determine how mice react to a frightening stimulus, showing that deciding whether or not to freeze in fear is a more complex task for our brains than we realised.
Heidelberg, 5 August 2010 Constant overlap Scientists at EMBL Heidelberg have uncovered the molecular mechanism that determines the size of anti-parallel microtubule overlaps in the spindle. In a study published today in Cell, they were able to reconstruct such overlaps in vitro, and identify two proteins which are sufficient to control the formation and size of this important spindle feature.
- The Scientist (F1000 ratings) , 21 September 2010 Top 7 in cell biology
Heidelberg, 3 August 2010 Supply and demand In a study published today in Cell Metabolism, scientists at EMBL Heidelberg have discovered that a group of proteins called IRPs ensure that iron balance is kept and as such are essential for cell survival. More specifically, they found that IRPs are required for the functioning of mitochondria, the cell’s energy factories.
Heidelberg, 4 July 2010 Digital Embryo gains wings Scientists at EMBL Heidelberg were able to capture fruit fly development on film, creating the Fly Digital Embryo. In work published today in Nature Methods, they were also the first to clearly record how a zebrafish’s eyes and midbrain are formed.
- Scientific American , 1 September 2010 'New Microscope Enables Real-Time 3-D Movies of Developing Embryos' [incl. Slide Show]
- New Scientist , 8 July 2010 'Hard-to-see fruit fly embryos brought to life in 3D'
- Die Welt (Germany) , 12 July 2010 'Wachsendes Gehirn erstmals als Film'
- Die Welt Kompakt (Germany) , 12 July 2010 ‘Forscher filmen erstmals ein wachsendes Gehirn’
- Bio Techniques , 26 July 2010 'Embryonic development imaged in 3D'
Heidelberg, 15 June 2010 Picture Release This image may bring to mind a patchwork quilt, or a picture taken from a gallery of abstract paintings, but the artisan behind it is actually Mother Nature, with a little help from scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.
- Quo magazine (Spain) , 15 June 2010 ‘Pez en formación’
Monterotondo, 31 May 2010 Making enough red blood cells Two small molecules ensure enough red blood cells are produced, scientists at EMBL Monterotondo and EMBL-EBI found in a study published today in the Journal of Experimental Medicine.
- Berliner Zeitung (Germany) , 4 June 2010 ‘Steuerung roter Blutkörperchen’
Heidelberg, 2 May 2010 Tags on, tags off The group of proteins called Polycomb complexes – which ensure correct embryonic development and play an important role in stem cell differentiation and cancer - has a new member, whose form of action surprised the EMBL Heidelberg scientists who identified it in a study published online today in Nature.
Heidelberg, 1 April 2010 Movies for the human genome Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off, thanks to work by researchers at EMBL Heidelberg and their collaborators in the Mitocheck consortium, in a study published today in Nature where they identify the genes involved in mitosis in humans.
- Nature News , 1 April 2009 ‘Lights, camera, action for cells’
- Nature Podcast , 1 April 2009 ‘Human genome 2.0’’
- BBC World Service Radio , 1 April 2009 ‘Science In Action - Gene videos' (00.52-06.00 min)
- Not Exactly Rocket Science , 1 April 2010 ‘Movies of life show the dance of living cells’’
- Transkript (Germany) , 1 April 2009 ‘Meldung des Tages: Neue Video-Datenbank zu menschlichen Knock-out-Zellen online’’
Heidelberg, 18 March 2010 What makes us unique? Not only our genes Scientists at EMBL Heidelberg and Yale and Stanford Universities have found that we differ from each other mainly because of differences not in our genes, but in how they’re regulated – turned on or off, for instance. Their study is published online today in Science.
- SWR 2 (Germany) , 30 March 2009 ‘Was uns einzigartig macht’
- Australian Life Scientist magazine , 19 March 2009 ‘Gene regulation, not just genes, make us unique’
- New Scientist , 19 March 2009 ‘ 'Junk' DNA gets credit for making us who we are’
Heidelberg, 16 March 2010 The Nordic EMBL Partnership for Molecular Medicine officially inaugurates the Institute for Molecular Medicine Finland in Helsinki Today, the Nordic EMBL Partnership for Molecular Medicine officially inaugurates the Institute for Molecular Medicine Finland (FIMM) in Helsinki. The partnership was initiated in 2007 and is dedicated to research in molecular medicine, investigation of the molecular basis of disease and the discovery of new treatments.
Heidelberg, 9 March 2010 New training and conference centre for the life sciences at EMBL in Heidelberg The German Minister for Education and Research officially opens the EMBL Advanced Training Centre – Funding comes from the German Ministry for Education and Research, the Klaus Tschira Foundation, the federal state of Baden-Württemberg and EMBL’s member states.
Heidelberg, 4 March 2010 Bacterial balance that keeps us healthy At 3.3 million, microbial genes in our gut outnumber previous estimates for the whole of the human body, EMBL scientists and their collaborators found when establishing a reference gene set for the human gut microbiome.
- Transkript (Germany), April 2010 'Forscher entschlüsseln humanes Darmmikrobiom’
Heidelberg, 31 January 2010 MicroRNA: a glimpse into the past The last ancestor we shared with worms, which roamed the seas around 600 million years ago, may already have had a sophisticated brain. Fossils cannot give us this information, but scientists at EMBL Heidelberg obtained it by studying small molecules called microRNAs. Their findings are published today in Nature.
- ORF Radio online (Austria) , 1 February 2010 ‘Gemeinsamkeiten von Würmern und Menschen’
Hamburg, 26 January 2010 How to shoot the messenger By determining the structure of DAPK bound to calmodulin, scientists from EMBL Hamburg have found a way to hack into a vital cellular communications system, raising the possibility of developing new drugs to tackle disorders like neurodegeneration, cancer and cardiovascular disease.
- ESRF News , 1 March 2010 'Communications system hacked'
- Hamburger Abendblatt (Germany) , 27 January 2009 ‘Hamburger entschlüsseln Enzym - neuer Ansatz für Krebsmedikamente’
Hinxton, 18 January 2010 Open access drug discovery database launches with half a million compounds ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new drugs in the clinic.
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