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Hamburg, 7 August 2014 Double act How can you find the same thing both attractive and repulsive? For growing neurons, the answer is in how they engage with it. The findings, published online today in Neuron, stem from the 3D structure of Netrin-1 bound to one of the sensor molecules – receptors – the cell uses to detect it. The work, by scientists at EMBL Hamburg, the Dana-Farber Cancer Institute and Peking University could also have implications for cancer treatment.
Hamburg, 24 July 2014 Fighting bacteria – with viruses Research published today in PLOS Pathogens reveals how viruses called bacteriophages destroy the bacterium Clostridium difficile (C. diff), which is becoming a serious problem in hospitals and healthcare institutes, due to its resistance to antibiotics. The study by scientists at EMBL Hamburg could help bring about a new way of fighting this and other bacteria.
Heidelberg, 3 July 2014 EMBL and EMBO to host anniversary science and policy meeting Scientists, politicians and policy makers met at the EMBL Advanced Training Centre in Heidelberg, Germany, on Wednesday 2 July and Thursday 3 July for the EMBO-EMBL Anniversary Science and Policy Meeting. The event will feature scientific talks from researchers, the participation of European science ministers, and sessions on policy issues such as excellence and inclusion.
Heidelberg, 2 July 2014 Surprisingly stable long-distance relationships Contrary to what was thought, sequences of DNA called enhancers find their targets long before they are activated during embryonic development, scientists EMBL Heidelberg have found. Their study, published in Nature, also reveals that, surprisingly, the degree of complexity of enhancers’ interactions in the fruit fly is comparable to what is seen in vertebrates.
Heidelberg, 22 June 2014 Cancer by remote-control One of the deadliest forms of paediatric brain tumour, Group 3 medulloblastoma, is linked to a variety of large-scale DNA rearrangements which all have the same overall effect on specific genes located on different chromosomes. The finding, by scientists at EMBL Heidelberg and collaborators, is published online today in Nature.
Heidelberg/Prague, 10 June 2014 Czech Republic becomes EMBL’s 21st member state Forty years after its foundation, EMBL announces its 21st member state: the Czech Republic. Building on a successful bilateral relationship, the Czech Republic’s membership grants Czech scientists access to EMBL’s state-of-the-art instruments, facilities and world-class training programmes.
Heidelberg, 25 May 2014 Insights into genetics of cleft lip Scientists in the Spitz group at EMBL Heidelberg have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face. The study, published today in Nature Genetics, helps understand the genetic causes of cleft lip and cleft palate, which are among the most common congenital malformations in humans.
Hinxton, 9 May 2014 How immune cells use steroids Researchers at the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute have discovered that some immune cells turn themselves off by producing a steroid. The findings, published in Cell Reports, have implications for the study of cancers, autoimmune diseases and parasitic infections.
Hinxton, 27 March 2014 Where do you start when developing a new medicine? A pioneering public-private research initiative between GSK, the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute is to harness the power of ‘big data’ and genome sequencing to improve the success rate for discovering new medicines. The new Centre for Therapeutic Target Validation (CTTV) will aim to address a wide range of human diseases and will share its data openly in the interests of accelerating drug discovery.
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