Heidelberg, 21 December 2012 Of leeches and men Researchers from EMBL and collaborators, have more than doubled our knowledge on the genomes of Lophotrochozoans, a branch of the animal kingdom has often been neglected by scientists. Their results, published in Nature in December, describe the genomes of three Lophotrochozoan species, and their evolutionary relationships to the other branches of the animal kingdom. These findings set the frame for future research on the biodiversity of this group, as well as on its evolution from our last common ancestor.
Hamburg, 1 December 2012 Unzipping melanocyte regulation Scientists from EMBL Hamburg have resolved the structure of a transcription factor crucial in the development of melanoma. The data published today in the journal Genes and Development provide a rational basis for the treatment of important hereditary diseases and cancer by targeting MITF.
Grenoble, 26 October 2012 The proteins came in two by two Female fruit flies have two copies of the X chromosome, while males have only one. For the male flies to be able to make up for this shortage, 2 copies of a particular protein called Msl1 have to pair up, EMBL Grenoble scientists and colleagues have discovered.
Heidelberg, 17 August 2012 Mini screening factories EMBL scientists have developed a novel technique for screening antibodies for a specific function – such as the ability to inhibit a drug target – with speed and at the single cell level. The study, published in July in PNAS, could pave the way to the direct screening of antibodies from human donors, thereby accelerating the development of new treatments for diseases.