Small molecules play essential roles in many areas of basic research and are often used to address important biological questions. The aim of our Chemical Biology Core Facility is to enable research groups to address biological questions by identifying and developing “biotool” compounds against novel targets.
We can assist groups in development of primary and secondary assays for screening against our in-house compound library and guide them through the process of developing tool compounds for their specific target. Chemical optimisation projects can be done in collaboration with our chemistry partners.
The facility is a collaboration between EMBL and the German Cancer Research Center, Heidelberg to provide the infrastructure and expertise to open up small molecule development to research groups at both the institutions.