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One of the PSB technical platforms.

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Partners: EMBL Grenoble; ESRF, ILL, the CEA-CNRS-UJF Institut de Biologie Structurale (IBS) and the UJF-EMBL-CNRS Unit of Virus Host Cell Interactions (UVHCI), Grenoble

The Partnership for Structural Biology (PSB) was established by a Memorandum of Understanding in 2002 to provide a unique environment for state-of-the-art integrated structural biology.

The partners are EMBL Grenoble, the European Synchrotron Radiation Facility (ESRF), the Institut Laue Langevin (ILL), and the Institut de Biologie Structurale (IBS), which is supported by the French CEA, the French National Centre for Scientific Research (CNRS) and the University of Grenoble (University Joseph Fourier, UJF). In 2008 a fifth partner, the newly established Unit of Virus Host Cell Interactions (UVHCI) joined the PSB.

The PSB combines the skills and resources of these five leading institutes, sharing a common goal and enabling a fully interdisciplinary approach involving biologists, crystallographers, chemists, engineers, computer specialists and experienced managers. This PSB provided the framework to enable integrated European programmes in state-of-the-art structural biology to be pursued, and today the collaboration between EMBL and the other PSB members plays a determinative role in the process of recognising the PSB as one of the French INSTRUCT Centers.

PSB’s research in structural biology covers three major areas: host-pathogen interactions, stress responses in prokaryotes and gene regulation, with many PSB projects assigned to more than one area. The science-driven development of methodologies and instrumentation represents another equally important component of PSB’s science.

The technical platforms are the cornerstone of PSB and represent a significant collective investment. Currently PSB accommodates 14 technical platforms on the Polygone Scientifique Campus in Grenoble, and a 15th platform in biophysics is currently being developed.

PSB actively encourages academic visitors to make use of the state-of-the-art infrastructures, particularly for training purposes.