Top image

Seminars

Seminar Colour Guide:              
Print version: This Week Next Week
External Faculty Speaker
Monday, 3 November 2014, 13:00 Add to calendar Epigenetic Targets in Cancer Kristian Helin University of Copenhagen, Denmark Host: Eileen Furlong
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Wednesday, 5 November 2014, 16:00 Add to calendar Integration of actin and adhesion dynamics in cell migration Clare M. Waterman NIH , Cell Biology and Physiology Center, Bethesda, USA Host: Peter Lenart
Large Operon, EMBL Heidelberg
Abstract: During cell migration, forces originating in the actin cytoskeleton are transmitted across macromolecular focal adhesions (FAs) to the extracellular matrix to generate the rearward traction forces that propel forward cell movement. FAs are organized into three-dimensional nano-domains with varying protein composition and mechanical signatures, and force transduction across FAs is regulated by a three dimensional molecular clutch consisting of talin and vinculin. Individual FAs dynamically sample substrate stiffness by applying fluctuating pulling forces and act as mechanosensors to guide cell migration. I will discuss our work over the past 15 years using quantitative light microscopy to tests predictions of the "Molecular Clutch Hypothesis Tags: Cell Biology
External Faculty Speaker
Friday, 7 November 2014, 10:00 Add to calendar Protein localisation regulates kinetochore homeostasis Peter Thorpe MRC National Institute for Medical Research, United Kingdom Host: Christian Häring
Small Operon, EMBL Heidelberg
External Faculty Speaker
Friday, 7 November 2014, 11:00 Add to calendar Systems biology in 3D space - enter the morphome John Lucocq University of St. Andrews, School of Medicine and Biology, United Kingdom Host: Yannick Schwab
Small Operon, EMBL Heidelberg
Tags: Cell Biology
External Faculty Speaker
Friday, 14 November 2014, 13:00 Add to calendar The 14th Public MMPU Research Day The 14th Public MMPU Research Day - MMPU members and invited guest speakers Molecular Medicine Partnership Unit Heidelberg Host: Matthias Hentze and Andreas Kulozik
Frauen u. Hautklinik, Conf. Room 272, INF 440, HD
Tags: Molecular Medicine
External Faculty Speaker
Monday, 17 November 2014, 11:00 Add to calendar The role od CDC6 in mitotic activation of CDK1 Jacek Kubiak University of Rennes 1, France Host: Takashi Hiiragi
Small Operon, EMBL Heidelberg
Abstract: CDC6 is essential for S-phase to initiate DNA replication, it also regulates M-phase exit by inhibiting the activity of the major M-phase protein kinase CDK1. We show that addition of recombinant CDC6 to Xenopus embryo cycling extract delays the M-phase entry and inhibits CDK1 during the whole M-phase. Down regulation of endogenous CDC6 accelerates the M-phase entry, abolishes the initial slow and progressive phase of histone H1 kinase activation and increases the level of CDK1 activity during the M-phase. All these effects are fully rescued by the addition of recombinant CDC6 to the extracts. Thus, CDC6 behaves as CDK1 inhibitor regulating the M-phase entry and progression via limiting the level of CDK1 activity. We propose a novel mechanism of M-phase entry controlled by CDC6 and counterbalancing cyclin B-mediated CDK1 activation. In conclusion, CDK1 activation proceeds with concomitant inhibition by CDC6-dependent mechanism, which tunes the timing of the M-phase entry during the embryonic cell cycle.
External Faculty Speaker
Thursday, 20 November 2014, 11:00 Add to calendar To be announced Jean-Paul Vincent MRC London Host: Stefano De Renzis
Small Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Monday, 19 January 2015, 11:00 Add to calendar To be announced Kenneth S. Zaret University of Pennsylvania, , Perelman School of Medicine, Dept. of Cell and Developmental Biology, USA Host: Eileen Furlong
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Monday, 9 February 2015, 11:00 Add to calendar To be announced Martin Fussenegger ETH Zurich, Department of Biosystems Science and Engineering, , Switzerland Host: Kiran Patil
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Friday, 17 April 2015, 11:00 Add to calendar To be announced Stefano Piccolo University of Padua, Italy, Dept. of Molecular Medicine, Italy Host: Darren Gilmour
Large Operon, EMBL Heidelberg
Tags: Cell Biology
EMBL Distinguished Visitor Lecture
Thursday, 30 April 2015, 11:00 Add to calendar To be announced Caroline DEAN John Innes Centre, Dept. of Cell & Developmental Biology, Norwich, UK, United Kingdom Host: Anne Ephrussi
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Tuesday, 12 May 2015, 11:00 Add to calendar To be announced Elly Tanaka Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany Host: Anne Ephrussi
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Tuesday, 22 September 2015, 11:00 Add to calendar To be announced Christine Holt University of Cambridge, UK, Dept. of Developmental Neuroscience, United Kingdom Host: Jeroen Krijgsveld
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Wednesday, 30 September 2015, 16:00 Add to calendar To be announced Mary Beckerle Huntsman Cancer Institute, Salt Lake City, Host: Francois Nedelec
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Monday, 5 October 2015, 11:00 Add to calendar To be announced Raymond E. Goldstein University of Cambridge, Dept. of Applied Mathematics and Theoretical Physics, Center for Mathematical Sciences, United Kingdom Host: Predocs
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Tuesday, 27 October 2015, 11:00 Add to calendar To be announced Cynthia Wolberger John Hopkins University School of Medicine, Dept. of Biophysics and Biophysical Chemistry, Baltimore, USA Host: Christoph Mueller
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Thursday, 10 December 2015, 11:00 Add to calendar To be announced Marianne Bronner California Institute of Technology, Division of Biology, Pasadena, USA Host: Detlev Arendt
Large Operon, EMBL Heidelberg