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Seminars

Seminar Colour Guide:              
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External Faculty Speaker
Friday, 5 September 2014, 11:00 Add to calendar in situ identification and characterization of bipotent stem cells in the mammary gland: Insights from 3D imaging Anne Rios Walter and Eliza Hall Institute of Medical Research Host: Anne Ephrussi
Small Operon, EMBL Heidelberg
Seminar given by an external postdoc
Monday, 15 September 2014, 15:00 Add to calendar The variation landscape of post-translational modifications in population and disease Juri Reimand University of Toronto, Donnelly Centre for Cellular and Biomolecular Research, Canada Host: Leopold Parts
Small Operon, EMBL Heidelberg
Abstract: Individual human genomes differ in numerous and infrequent changes such as single nucleotide variants. Understanding the function of variation and impact on phenotypes is an important challenge. We studied variation and disease mutations affecting post-translational modification (PTM) sites using data from population sequencing and cancer genomics projects. We found that PTM sites representing >11% of protein sequence are under specific evolutionary constraint in the human population. These sequence regions are also enriched in inherited disease variants and informative of cancer driver genes, pathways, and clinical signatures. We highlight genes where disease mutations significantly accumulate in PTM regions, analyze their network context to predict losses and gains of interactions with PTM enzymes, and integrate pharmacological information to predict new drug candidates for multiple diseases. This work aids understanding of the selective forces acting on protein-coding genome sequence and provides an integrative framework for predicting variant function in population and disease.
Science and Society
Monday, 22 September 2014, 14:00 Add to calendar The Long History of Evolution - what can we learn about science and originality? Rebecca Stott University of East Anglia, United Kingdom Host: Halldór Stefánsson
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Thursday, 25 September 2014, 16:00 Add to calendar To be announced Janet Rossant University of Toronto, Department of Molecular Genetics Host: Takashi Hiiragi
Large Operon, EMBL Heidelberg
Seminar given by an external postdoc
Friday, 26 September 2014, 11:00 Add to calendar Inhibitors of intracellular trafficking active against Shiga toxins and Ricin Neetu Gupta DSV/iBiTec-S/SIMOPRO, Gif sur Yvette, France, France Host: Rainer Pepperkok
Room 13-518 a + b, EMBL Heidelberg
External Faculty Speaker
Monday, 29 September 2014, 11:00 Add to calendar Protein Engineering and Folding with non-natural amino acids Marina Rubini University of Konstanz, Germany, Germany Host: Jonas Ries
Small Operon, EMBL Heidelberg
Tags: Cell Biology
Seminar given by an external postdoc
Tuesday, 30 September 2014, 11:00 Add to calendar To be announced Martin Wuehr Harvard Medical School, Department of Systems Biology Host: Peter Lenart
Small Operon, EMBL Heidelberg
Tags: Cell Biology
External Faculty Speaker
Monday, 6 October 2014, 13:00 Add to calendar To be announced Tomas Marques Bonet Universitat Pompeu Fabra, Barcelona, Spain Host: Jan Korbel
Small Operon, EMBL Heidelberg
External Faculty Speaker
Monday, 13 October 2014, 11:00 Add to calendar Evo-devo in a billion years time scale: using seaweeds to study the evolution and regulation of sexual life cycle Susana Coelho UMR 7139 CNRS--UPMC, France Host: Anne Ephrussi
Small Operon, EMBL Heidelberg
Science and Society
Tuesday, 14 October 2014, 18:00 Add to calendar Das Human Brain Project: Simulation und Realität Karlheinz Meier Universität Heidelberg, Germany Host: Halldór Stefánsson
Print Media Academy
External Faculty Speaker
Thursday, 16 October 2014, 11:00 Add to calendar To be announced Jan Lohmann Ruprecht-Karls-University Heidelberg Host: Marcus Heisler
Small Operon, EMBL Heidelberg
External Faculty Speaker
Thursday, 23 October 2014, 11:00 Add to calendar To be announced Enrico Coen John Innes Centre Host: Marcus Heisler
Small Operon, EMBL Heidelberg
Science and Society
Sunday, 26 October 2014, 11:00 Add to calendar Der Sonne entgegen wie unseren Vorfahren aus dem Meer ein Licht aufging Silvia Rohr EMBL, Germany Host: Lena Raditsch
ATC Auditorium, EMBL Heidelberg
Science and Society
Tuesday, 28 October 2014, 15:00 Add to calendar Play and Creativity Patrick Bateson University of Cambridge, United Kingdom Host: Halldór Stefánsson
Large Operon, EMBL Heidelberg
External Faculty Speaker
Monday, 3 November 2014, 13:00 Add to calendar To be announced Kristian Helin University of Copenhagen, Denmark Host: Eileen Furlong
Small Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Wednesday, 5 November 2014, 16:00 Add to calendar To be announced Clare M. Waterman NIH , Cell Biology and Physiology Center, Bethesda, USA Host: Peter Lenart
Large Operon, EMBL Heidelberg
Tags: Cell Biology
External Faculty Speaker
Friday, 7 November 2014, 11:00 Add to calendar To be announced John Lucocq University of St. Andrews, School of Medicine and Biology, United Kingdom Host: Yannick Schwab
Small Operon, EMBL Heidelberg
Tags: Cell Biology
External Faculty Speaker
Thursday, 20 November 2014, 11:00 Add to calendar To be announced Jean-Paul Vincent MRC London Host: Stefano De Renzis
Small Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Monday, 19 January 2015, 16:00 Add to calendar To be announced Kenneth S. Zaret University of Pennsylvania, , Perelman School of Medicine, Dept. of Cell and Developmental Biology Host: Eileen Furlong
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Monday, 9 February 2015, 16:00 Add to calendar To be announced Martin Fussenegger ETH Zurich, Department of Biosystems Science and Engineering, Host: Kiran Patil
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Thursday, 30 April 2015, 16:00 Add to calendar To be announced Caroline DEAN John Innes Centre, Dept. of Cell & Developmental Biology, Norwich, UK, United Kingdom Host: Anne Ephrussi
Large Operon, EMBL Heidelberg
EMBL Distinguished Visitor Lecture
Wednesday, 30 September 2015, 16:00 Add to calendar To be announced Mary Beckerle Huntsman Cancer Institute, Salt Lake City, Host: Francois Nedelec
Large Operon, EMBL Heidelberg