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Staff at EMBL

Dr. Jan Ellenberg

Head of Unit and Senior Scientist
Cell Biology and Biophysics Ellenberg Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Biography

PhD 1998, Freie Universität Berlin.
Postdoctoral research at the Cell Biology and Metabolism Branch, NICHD, NIH, Bethesda.
Group leader at EMBL since 1999.
Head of Gene Expression Unit since 2006.
Head of Cell Biology and Biophysics Unit since 2010.

Publications

A quantitative liposome microarray to systematically characterize protein-lipid interactions. Saliba, A.E., Vonkova, I., Ceschia, S., Findlay, G.M., Maeda, K., Tischer, C., Deghou, S., van Noort, V., Bork, P., Pawson, T., Ellenberg, J. & Gavin, A.C. Nat Methods. 2014 Jan;11(1):47-50. doi: 10.1038/nmeth.2734. Epub 2013 Nov 24. Europe PMC

Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance. Walter, A., Chapuis, C., Huet, S. & Ellenberg, J. J Struct Biol. 2013 Dec;184(3):445-53. doi: 10.1016/j.jsb.2013.10.004. Epub 2013Oct 18. Europe PMC

Wapl is an essential regulator of chromatin structure and chromosome segregation. Tedeschi, A., Wutz, G., Huet, S., Jaritz, M., Wuensche, A., Schirghuber, E., Davidson, I.F., Tang, W., Cisneros, D.A., Bhaskara, V., Nishiyama, T., Vaziri, A., Wutz, A., Ellenberg, J. & Peters, J.M. Nature. 2013 Sep 26;501(7468):564-8. doi: 10.1038/nature12471. Epub 2013 Aug 25. Europe PMC

Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging. Szymborska, A., de Marco, A., Daigle, N., Cordes, V.C., Briggs, J.A. & Ellenberg, J. Science. 2013 Aug 9;341(6146):655-8. doi: 10.1126/science.1240672. Epub 2013 Jul11. Europe PMC

EGF-Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival. Mardin, B.R., Isokane, M., Cosenza, M.R., Kramer, A., Ellenberg, J., Fry, A.M. & Schiebel, E. Dev Cell. 2013 May 13;25(3):229-40. doi: 10.1016/j.devcel.2013.03.012. Epub 2013May 2. Europe PMC

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay. Pau, G., Walter, T., Neumann, B., Heriche, J.K., Ellenberg, J. & Huber, W. BMC Bioinformatics. 2013 Oct 16;14:308. doi: 10.1186/1471-2105-14-308. Europe PMC

GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. Scolz, M., Widlund, P.O., Piazza, S., Bublik, D.R., Reber, S., Peche, L.Y., Ciani, Y., Hubner, N., Isokane, M., Monte, M., Ellenberg, J., Hyman, A.A., Schneider, C. & Bird, A.W. PLoS One. 2012;7(12):e51259. doi: 10.1371/journal.pone.0051259. Epub 2012 Dec 7. Europe PMC

A fractal model for nuclear organization: current evidence and biological implications. Bancaud, A., Lavelle, C., Huet, S. & Ellenberg, J. Nucleic Acids Res. 2012 Oct;40(18):8783-92. doi: 10.1093/nar/gks586. Epub 2012Jul 11. Europe PMC

Mitotic lamin disassembly is triggered by lipid-mediated signaling. Mall, M., Walter, T., Gorjanacz, M., Davidson, I.F., Nga Ly-Hartig, T.B., Ellenberg, J., Mattaj, I.W. J Cell Biol. 2012 Sep 17;198(6):981-90. doi: 10.1083/jcb.201205103. Europe PMC

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development. Courtois, A., Schuh, M., Ellenberg, J. & Hiiragi, T. J Cell Biol. 2012 Aug 6;198(3):357-70. Epub 2012 Jul 30. Europe PMC

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Simpson, J.C., Joggerst, B., Laketa, V., Verissimo, F., Cetin, C., Erfle, H., Bexiga, M.G., Singan, V.R., Heriche, J.K., Neumann, B., Mateos, A., Blake, J., Bechtel, S., Benes, V., Wiemann, S., Ellenberg, J. & Pepperkok, R. Nat Cell Biol. 2012 Jun 3;14(7):764-74. doi: 10.1038/ncb2510. Europe PMC

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1. Moudry, P., Lukas, C., Macurek, L., Neumann, B., Heriche, J.K., Pepperkok, R., Ellenberg, J., Hodny, Z., Lukas, J. & Bartek, J. Cell Death Differ. 2012 May;19(5):798-807. doi: 10.1038/cdd.2011.150. Epub 2011Nov 11. Europe PMC

The quantitative proteome of a human cell line. Beck, M., Schmidt, A., Malmstroem, J., Claassen, M., Ori, A., Szymborska, A., Herzog, F., Rinner, O., Ellenberg, J. & Aebersold, R. Mol Syst Biol. 2011 Nov 8;7:549. doi: 10.1038/msb.2011.82. Europe PMC

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases. Ritzerfeld, J., Remmele, S., Wang, T., Temmerman, K., Brugger, B., Wegehingel, S., Tournaviti, S., Strating, J.R., Wieland, F.T., Neumann, B., Ellenberg, J., Lawerenz, C., Hesser, J., Erfle, H., Pepperkok, R. & Nickel, W. Genome Res. 2011 Nov;21(11):1955-68. doi: 10.1101/gr.116087.110. Epub 2011 Jul27. Europe PMC

Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes. Kitajima, T.S., Ohsugi, M. & Ellenberg, J. Cell. 2011 Aug 19;146(4):568-81. doi: 10.1016/j.cell.2011.07.031. Europe PMC

A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells. Ng, K., Daigle, N., Bancaud, A., Ohhata, T., Humphreys, P., Walker, R., Ellenberg, J. & Wutz, A. Mol Biol Cell. 2011 Jul;22(14):2634-2645. Epub 2011 May 25. Europe PMC

Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators. Sironi L,Solon J,Conrad C,Mayer TU,Brunner D,Ellenberg J Cytoskeleton (Hoboken). 2011 May;68(5):266-78. doi: 10.1002/cm.20510. Epub 2011Apr 13. Europe PMC

Intracellular transport by an anchored homogeneously contracting F-actin meshwork. Mori, M., Monnier, N., Daigle, N., Bathe, M., Ellenberg, J. & Lenart, P. Curr Biol. 2011 Apr 12;21(7):606-11. Europe PMC

A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase. Bolhy, S., Bouhlel, I., Dultz, E., Nayak, T., Zuccolo, M., Gatti, X., Vallee, R., Ellenberg, J. & Doye, V. J Cell Biol. 2011 Mar 7;192(5):855-71. doi: 10.1083/jcb.201007118. Europe PMC

Micropilot: automation of fluorescence microscopy-based imaging for systems biology. Conrad, C., Wunsche, A., Tan, T.H., Bulkescher, J., Sieckmann, F., Verissimo, F., Edelstein, A., Walter, T., Liebel, U., Pepperkok, R. & Ellenberg, J. Nat Methods. 2011 Mar;8(3):246-9. doi: 10.1038/nmeth.1558. Epub 2011 Jan 23. Europe PMC

Fluorescence perturbation techniques to study mobility and molecular dynamics of proteins in live cells: FRAP, photoactivation, photoconversion, and FLIP. Bancaud, A., Huet, S., Rabut, G. & Ellenberg, J. Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.top90. doi: 10.1101/pdb.top90. Europe PMC

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. Landsverk, H.B., Mora-Bermudez, F., Landsverk, O.J., Hasvold, G., Naderi, S., Bakke, O., Ellenberg, J., Collas, P., Syljuasen, R.G. & Kuntziger, T. EMBO Rep. 2010 Nov;11(11):868-75. Epub 2010 Oct 1. Europe PMC

Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase. Dultz, E. & Ellenberg, J. J Cell Biol. 2010 Oct 4;191(1):15-22. Epub 2010 Sep 27. Europe PMC

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. Held, M., Schmitz, M.H., Fischer, B., Walter, T., Neumann, B., Olma, M.H., Peter, M., Ellenberg, J. & Gerlich, D.W. Nat Methods. 2010 Sep;7(9):747-54. doi: 10.1038/nmeth.1486. Epub 2010 Aug 8. Europe PMC

High-throughput microscopy using live mammalian cells. Terjung, S., Walter, T., Seitz, A., Neumann, B., Pepperkok, R. & Ellenberg, J. Cold Spring Harb Protoc. 2010 Aug 1;2010(7):pdb.top84. doi: 10.1101/pdb.top84. Europe PMC

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. Walter, T., Held, M., Neumann, B., Heriche, J.K., Conrad, C., Pepperkok, R. & Ellenberg, J. J Struct Biol. 2010 Apr;170(1):1-9. doi: 10.1016/j.jsb.2009.10.004. Epub 2009 Oct23. Europe PMC

Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins, J.R., Toyoda, Y., Hegemann, B., Poser, I., Heriche, J.K., Sykora, M.M., Augsburg, M., Hudecz, O., Buschhorn, B.A., Bulkescher, J., Conrad, C., Comartin, D., Schleiffer, A., Sarov, M., Pozniakovsky, A., Slabicki, M.M., Schloissnig, S., Steinmacher, I., Leuschner, M., Ssykor, A., Lawo, S., Pelletier, L., Stark, H., Nasmyth, K., Ellenberg, J., Durbin, R., Buchholz, F., Mechtler, K., Hyman, A.A. & Peters, J.M. Science. 2010 Apr 30;328(5978):593-9. Epub 2010 Apr 1. Europe PMC

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Neumann, B., Walter, T., Heriche, J.K., Bulkescher, J., Erfle, H., Conrad, C., Rogers, P., Poser, I., Held, M., Liebel, U., Cetin, C., Sieckmann, F., Pau, G., Kabbe, R., Wünsche, A., Satagopam, V., Schmitz, M.H., Chapuis, C., Gerlich, D.W., Schneider, R., Eils, R., Huber, W., Peters, J.M., Hyman, A.A., Durbin, R., Pepperkok, R. & Ellenberg, J. Nature. 2010 Apr 1;464(7289):721-7. Europe PMC

Visualization of image data from cells to organisms. Walter, T., Shattuck, D.W., Baldock, R., Bastin, M.E., Carpenter, A.E., Duce, S., Ellenberg, J., Fraser, A., Hamilton, N., Pieper, S., Ragan, M.A., Schneider, J.E., Tomancak, P. & Heriche, J.K. Nat Methods. 2010 Mar;7(3 Suppl):S26-41. Europe PMC

Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy. Huet, S., Avilov, S.V., Ferbitz, L., Daigle, N., Cusack, S. & Ellenberg, J. J Virol. 2010 Feb;84(3):1254-64. Epub 2009 Nov 11. Europe PMC

Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin. Bancaud, A., Huet, S., Daigle, N., Mozziconacci, J., Beaudouin, J. & Ellenberg, J. EMBO J. 2009 Dec 16;28(24):3785-98. Epub . Europe PMC

Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time. Harder, N., Mora-Bermudez, F., Godinez, W.J., Wünsche, A., Eils, R., Ellenberg, J. & Rohr, K. Genome Res. 2009 Nov;19(11):2113-24. Epub 2009 Oct 1. Europe PMC

Formation of the nuclear envelope permeability barrier studied by sequential photoswitching and flux analysis. Dultz, E., Huet, S. & Ellenberg, J. Biophys J. 2009 Oct 7;97(7):1891-7. Europe PMC

Chromophore-assisted laser inactivation of alpha- and gamma-tubulin SNAP-tag fusion proteins inside living cells. Keppler, A. & Ellenberg, J. ACS Chem Biol. 2009 Feb 20;4(2):127-38. doi: 10.1021/cb800298u. Europe PMC

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Doil, C., Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D.H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, J. & Lukas, C. Cell. 2009 Feb 6;136(3):435-46. Europe PMC

A new model for asymmetric spindle positioning in mouse oocytes. Schuh, M. & Ellenberg, J. Curr Biol. 2008 Dec 23;18(24):1986-92. Epub 2008 Dec 8. Europe PMC

Sun1 forms immobile macromolecular assemblies at the nuclear envelope. Lu, W., Gotzmann, J., Sironi, L., Jaeger, V.M., Schneider, M., Luke, Y., Uhlen, M., Szigyarto, C.A., Brachner, A., Ellenberg, J., Foisner, R., Noegel, A.A. & Karakesisoglou, I. Biochim Biophys Acta. 2008 Dec;1783(12):2415-26. Epub 2008 Sep 19. Europe PMC

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates. Erfle, H., Neumann, B., Rogers, P., Bulkescher, J., Ellenberg, J. & Pepperkok, R. J Biomol Screen. 2008 Aug;13(7):575-80. Epub 2008 Jul 3. Europe PMC

Nuclear pore complex assembly through the cell cycle: regulation and membrane organization. Antonin, W., Ellenberg, J. & Dultz, E. FEBS Lett. 2008 Jun 18;582(14):2004-16. Epub 2008 Mar 6. Europe PMC

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase. Tegha-Dunghu, J., Neumann, B., Reber, S., Krause, R., Erfle, H., Walter, T., Held, M., Rogers, P., Hupfeld, K., Ruppert, T., Ellenberg, J. & Gruss, O.J. J Cell Sci. 2008 May 15;121(Pt 10):1718-26. Epub 2008 Apr 29. Europe PMC

Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells. Dultz, E., Zanin, E., Wurzenberger, C., Braun, M., Rabut, G., Sironi, L. & Ellenberg, J. J Cell Biol. 2008 Mar 10;180(5):857-65. Epub 2008 Mar 3. Europe PMC

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes. Schuh, M. & Ellenberg, J. Cell. 2007 Aug 10;130(3):484-98. Europe PMC

lambda(N)-GFP: an RNA reporter system for live-cell imaging. Daigle, N. & Ellenberg, J. Nat Methods. 2007 Aug;4(8):633-6. Epub 2007 Jul 1. Europe PMC

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase. Mora-Bermudez, F., Gerlich, D. & Ellenberg, J. Nat Cell Biol. 2007 Jul;9(7):822-31. Epub 2007 Jun 10. Europe PMC

An RNAi screening platform to identify secretion machinery in mammalian cells. Simpson, J.C., Cetin, C., Erfle, H., Joggerst, B., Liebel, U., Ellenberg, J. & Pepperkok, R. J Biotechnol. 2007 Apr 30;129(2):352-65. Epub 2007 Jan 14. Europe PMC

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Tarendeau, F., Boudet, J., Guilligay, D., Mas, P.J., Bougault, C.M., Boulo, S., Baudin, F., Ruigrok, R.W., Daigle, N., Ellenberg, J., Cusack, S., Simorre, J.P. & Hart, D.J. Nat Struct Mol Biol. 2007 Mar;14(3):229-33. Epub 2007 Feb 25. Europe PMC

Measuring structural dynamics of chromosomes in living cells by fluorescence microscopy. Mora-Bermudez, F. & Ellenberg, J. Methods. 2007 Feb;41(2):158-67. Europe PMC

Reverse transfection on cell arrays for high content screening microscopy. Erfle, H., Neumann, B., Liebel, U., Rogers, P., Held, M., Walter, T., Ellenberg, J. & Pepperkok, R. Nat Protoc. 2007;2(2):392-9. Europe PMC

Minimizing the risk of reporting false positives in large-scale RNAi screens. Echeverri, C.J., Beachy, P.A., Baum, B., Boutros, M., Buchholz, F., Chanda, S.K., Downward, J., Ellenberg, J., Fraser, A.G., Hacohen, N., Hahn, W.C., Jackson, A.L., Kiger, A., Linsley, P.S., Lum, L., Ma, Y., Mathey-Prevot, B., Root, D.E., Sabatini, D.M., Taipale, J., Perrimon, N. & Bernards, R. Nat Methods. 2006 Oct;3(10):777-9. Europe PMC

High-throughput fluorescence microscopy for systems biology. Pepperkok, R. & Ellenberg, J. Nat Rev Mol Cell Biol. 2006 Sep;7(9):690-6. Epub 2006 Jul 19. Europe PMC

Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication. Gerlich, D., Koch, B., Dupeux, F., Peters, J.M. & Ellenberg, J. Curr Biol. 2006 Aug 8;16(15):1571-8. Europe PMC

Fluorophores for live cell imaging of AGT fusion proteins across the visible spectrum. Keppler, A., Arrivoli, C., Sironi, L. & Ellenberg, J. Biotechniques. 2006 Aug;41(2):167-70, 172, 174-5. Europe PMC

Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Kudo, N.R., Wassmann, K., Anger, M., Schuh, M., Wirth, K.G., Xu, H., Helmhart, W., Kudo, H., McKay, M., Maro, B., Ellenberg, J., de Boer, P. & Nasmyth, K. Cell. 2006 Jul 14;126(1):135-46. Europe PMC

NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Ribbeck, K., Groen, A.C., Santarella, R., Bohnsack, M.T., Raemaekers, T., Kocher, T., Gentzel, M., Gorlich, D., Wilm, M., Carmeliet, G., Mitchison, T.J., Ellenberg, J., Hoenger, A. & Mattaj, I.W. Mol Biol Cell. 2006 Jun;17(6):2646-60. Epub 2006 Mar 29. Europe PMC

High-throughput RNAi screening by time-lapse imaging of live human cells. Neumann, B., Held, M., Liebel, U., Erfle, H., Rogers, P., Pepperkok, R. & Ellenberg, J. Nat Methods. 2006 May;3(5):385-90. Europe PMC

Nuclear actin: a lack of export allows formation of filaments. Schuh, M. & Ellenberg, J. Curr Biol. 2006 May 9;16(9):R321-3. Europe PMC

Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. Beaudouin, J., Mora-Bermudez, F., Klee, T., Daigle, N. & Ellenberg, J. Biophys J. 2006 Mar 15;90(6):1878-94. Epub 2005 Dec 30. Europe PMC

Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells. Gerlich, D., Hirota, T., Koch, B., Peters, J.M. & Ellenberg, J. Curr Biol. 2006 Feb 21;16(4):333-44. Europe PMC

Monitoring the permeability of the nuclear envelope during the cell cycle. Lenart, P. & Ellenberg, J. Methods 2006 Jan;38(1):17-24. Europe PMC

A contractile nuclear actin network drives chromosome congression in oocytes. Lenart, P., Bacher, C.P., Daigle, N., Hand, A.R., Eils, R., Terasaki, M. & Ellenberg, J. Nature 2005 Aug 11;436(7052):812-8. Epub 2005 Jul 13. Europe PMC

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35. Chusainow, J., Ajuh, P.M., Trinkle-Mulcahy, L., Sleeman, J.E., Ellenberg, J. & Lamond, A.I. RNA 2005 Aug;11(8):1201-14. Europe PMC

Photobleaching techniques to study mobility and molecular dynamics of proteins in live cells: FRAP, iFRAP and FLIP. Rabut, G. & Ellenberg, J. In "Live Cell Imaging: A Laboratory Manual Vol. 1", Goldman, R.D. and Spector, D.L., (Eds.), 101-127. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 2005

Distinct functions of condensin I and II in mitotic chromosome assembly. Hirota, T., Gerlich, D., Koch, B., Ellenberg, J. & Peters, J.M. J Cell Sci 2004 Dec 15;117(Pt 26):6435-45. Epub 2004 Nov 30. Europe PMC

LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly. Dechat, T., Gajewski, A., Korbei, B., Gerlich, D., Daigle, N., Haraguchi, T., Furukawa, K., Ellenberg, J. & Foisner, R. J Cell Sci 2004 Dec 1;117(Pt 25):6117-28. Epub 2004 Nov 16. Europe PMC

Mapping the dynamic organization of the nuclear pore complex inside single living cells. Rabut, G., Doye, V. & Ellenberg, J. Nat Cell Biol 2004 Nov;6(11):1114-21. Epub 2004 Oct 24. Europe PMC

Automatic real-time three-dimensional cell tracking by fluorescence microscopy. Rabut, G. & Ellenberg, J. J Microsc 2004 Nov;216(Pt 2):131-7. Europe PMC

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Sumara, I., Gimenez-Abian, J.F., Gerlich, D., Hirota, T., Kraft, C., de la Torre, C., Ellenberg, J. & Peters, J.M. Curr Biol 2004 Oct 5;14(19):1712-22. Europe PMC

Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. Bubulya, P.A., Prasanth, K.V., Deerinck, T.J., Gerlich, D., Beaudouin, J., Ellisman, M.H., Ellenberg, J. & Spector, D.L. J Cell Biol 2004 Oct 11;167(1):51-63. Europe PMC

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. Leung, A.K., Gerlich, D., Miller, G., Lyon, C., Lam, Y.W., Lleres, D., Daigle, N., Zomerdijk, J., Ellenberg, J. & Lamond, A.I. J Cell Biol 2004 Sep 13;166(6):787-800. Epub 2004 Sep 07. Europe PMC

The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. Loiodice, I., Alves, A., Rabut, G., Van Overbeek, M., Ellenberg, J., Sibarita, J.B. & Doye, V. Mol Biol Cell. 2004 Jul;15(7):3333-44. Epub 2004 May 14. Europe PMC

Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions. Giannone, G., Ronde, P., Gaire, M., Beaudouin, J., Haiech, J., Ellenberg, J. & Takeda, K. J Biol Chem 2004 Jul 2;279(27):28715-23. Epub 2004 Apr 21. Europe PMC

Regulation of sister chromatid cohesion between chromosome arms. Gimenez-Abian, J.F., Sumara, I., Hirota, T., Hauf, S., Gerlich, D., de la Torre, C., Ellenberg, J. & Peters, J.M. Curr Biol 2004 Jul 13;14(13):1187-93. Europe PMC

Automatic identification of subcellular phenotypes on human cell arrays. Conrad, C., Erfle, H., Warnat, P., Daigle, N., Lorch, T., Ellenberg, J., Pepperkok, R. & Eils, R. Genome Res. 2004 Jun;14(6):1130-6. Europe PMC

Dynamics of nuclear pore complex organization through the cell cycle. Rabut, G., Lenart, P. & Ellenberg, J. Curr Opin Cell Biol 2004 Jun;16(3):314-21. Europe PMC

RanBP2/Nup358 Provides a Major Binding Site for NXF1-p15 Dimers at the Nuclear Pore Complex and Functions in Nuclear mRNA Export. Forler, D., Rabut, G., Ciccarelli, F.D., Herold, A., Kocher, T., Niggeweg, R., Bork, P., Ellenberg, J. & Izaurralde, E. Mol Cell Biol 2004 Feb;24(3):1155-67. Europe PMC

Light microscopy of echinoderm embryos. Strickland, L., von Dassow, G., Ellenberg, J., Foe, V., Lenart, P. & Burgess, D. Methods Cell Biol 2004;74:371-409. Europe PMC

Dynamics of chromosome positioning during the cell cycle. Gerlich, D. & Ellenberg, J. Curr Opin Cell Biol. 2003 Dec;15(6):664-71. Europe PMC

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. Raemaekers, T., Ribbeck, K., Beaudouin, J., Annaert, W., Van Camp, M., Stockmans, I., Smets, N., Bouillon, R., Ellenberg, J. & Carmeliet, G. J Cell Biol 2003 Sep 15;162(6):1017-29. Europe PMC

4D imaging to assay complex dynamics in live specimens. Gerlich, D. & Ellenberg, J. Nat Cell Biol 2003 Sep;Suppl:S14-9. Europe PMC

Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. Lénart, P., Rabut, G., Daigle, N., Hand, A.R., Terasaki, M. & Ellenberg, J. J Cell Biol 2003 Mar 31;160(7):1055-68. Europe PMC

Global chromosome positions are transmitted through mitosis in mammalian cells. Gerlich, D., Beaudouin, J., Kalbfuss, B., Daigle, N., Eils, R. & Ellenberg, J. Cell 2003 Mar 21;112(6):751-64. Europe PMC

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Reid, G., Hubner, M.R., Metivier, R., Brand, H., Denger, S., Manu, D., Beaudouin, J., Ellenberg, J. & Gannon, F. Mol Cell 2003 Mar;11(3):695-707. Europe PMC

Nuclear envelope dynamics in oocytes: from germinal vesicle breakdown to mitosis. Lenart, P. & Ellenberg, J. Curr Opin Cell Biol 2003 Feb;15(1):88-95. Europe PMC

Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p. Kruse, C., Jaedicke, A., Beaudouin, J., Bohl, F., Ferring, D., Guttler, T., Ellenberg, J. & Jansen, R.P. J Cell Biol 2002 Dec 23;159(6):971-82. Europe PMC

Chromosomal association of Ran during meiotic and mitotic divisions. Hinkle, B., Slepchenko, B., Rolls, M.M., Walther, T.C., Stein, P.A., Mehlmann, L.M., Ellenberg, J. & Terasaki, M. J Cell Sci 2002 Dec 1;115(Pt 23):4685-93. Europe PMC

Remodelling the walls of the nucleus. Burke, B. & Ellenberg, J. Nat Rev Mol Cell Biol 2002 Jul;3(7):487-97. Europe PMC

Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation. Schmitt, A., Gutierrez, G.J., Lenart, P., Ellenberg, J. & Nebreda, A.R. FEBS Lett 2002 May 8;518(1-3):23-8. Europe PMC

Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Beaudouin, J., Gerlich, D., Daigle, N., Eils, R. & Ellenberg, J. Cell 2002 Jan 11;108(1):83-96. Europe PMC

Dynamics of nuclear envelope proteins during the cell cycle in mammalian cells. Ellenberg J. In "Dynamics of Nuclear Envelope Assembly in Embryos and Somatic Cells, Vol. 23", P. Collas (ed), 18-25. Landes Biosciences, Georgetown, Texas, USA, 2002.

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. Belgareh, N., Rabut, G., Bai, S.W., van Overbeek, M., Beaudouin, J., Daigle, N., Zatsepina, O.V., Pasteau, F., Labas, V., Fromont-Racine, M., Ellenberg, J. & Doye, V. J Cell Biol 2001 Sep 17;154(6):1147-60. Europe PMC

Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes in live cells. Gerlich, D., Beaudouin, J., Gebhard, M., Ellenberg, J. & Eils, R. Nat Cell Biol 2001 Sep;3(9):852-5. Europe PMC

Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells. Daigle, N., Beaudouin, J., Hartnell, L., Imreh, G., Hallberg, E., Lippincott-Schwartz, J. & Ellenberg, J. J Cell Biol 2001 Jul 9;154(1):71-84. Europe PMC

Nucleocytoplasmic transport: diffusion channel or phase transition? Rabut, G. & Ellenberg, J. Curr Biol 2001 Jul 24;11(14):R551-4. Europe PMC

A new model for nuclear envelope breakdown. Terasaki, M., Campagnola, P., Rolls, M.M., Stein, P.A., Ellenberg, J., Hinkle, B. & Slepchenko, B. Mol Biol Cell 2001 Feb;12(2):503-10. Europe PMC

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition. Dey, A., Ellenberg, J., Farina, A., Coleman, A.E., Maruyama, T., Sciortino, S., Lippincott-Schwartz, J. & Ozato, K. Mol Cell Biol 2000 Sep;20(17):6537-49 Europe PMC

Dynamics and retention of misfolded proteins in native ER membranes Nehls, S., Snapp, E.L., Cole, N.B., Zaal, K.J., Kenworthy, A.K., Roberts, T.H., Ellenberg, J., Presley, J.F., Siggia, E. & Lippincott-Schwartz, J. Nat Cell Biol 2000 May;2(5):288-95 Europe PMC

Golgi membranes are absorbed into and reemerge from the ER during mitosis Zaal, K.J., Smith, C.L., Polishchuk, R.S., Altan, N., Cole, N.B., Ellenberg, J., Hirschberg, K., Presley, J.F., Roberts, T.H., Siggia, E., Phair, R.D. & Lippincott-Schwartz, J. Cell 1999 Dec 10;99(6):589-601 Europe PMC

Dynamics and mobility of nuclear envelope proteins in interphase and mitotic cells revealed by green fluorescent protein chimeras. Ellenberg, J. & Lippincott-Schwartz, J. Methods 1999 Nov;19(3):362-72 Europe PMC

Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein. Ostlund, C., Ellenberg, J., Hallberg, E., Lippincott-Schwartz, J. & Worman, H.J. J Cell Sci 1999 Jun;112 ( Pt 11):1709-19 Europe PMC

Dual-colour imaging with GFP variants. Ellenberg, J., Lippincott-Schwartz, J. & Presley, J.F. Trends Cell Biol 1999 Feb;9(2):52-6 Europe PMC

Monitoring the dynamics and mobility of membrane proteins tagged with green fluorescent protein. Lippincott-Schwartz, J., Presley, J.F., Zaal, K.J., Hirschberg, K., Miller, C.D. & Ellenberg, J. Methods Cell Biol 1999;58:261-81 Europe PMC

Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells. Hirschberg, K., Miller, C.M., Ellenberg, J., Presley, J.F., Siggia, E.D., Phair, R.D. & Lippincott-Schwartz, J. J Cell Biol 1998 Dec 14;143(6):1485-503 Europe PMC

ZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulation. Sloan-Lancaster, J., Presley, J., Ellenberg, J., Yamazaki, T., Lippincott-Schwartz, J. & Samelson, L.E. J Cell Biol 1998 Nov 2;143(3):613-24 Europe PMC

Two-color green fluorescent protein time-lapse imaging. Ellenberg, J., Lippincott-Schwartz, J. & Presley, J.F. Biotechniques 1998 Nov;25(5):838-42, 844-6 Europe PMC

Retrograde transport of Golgi-localized proteins to the ER. Cole, N.B., Ellenberg, J., Song, J., DiEuliis, D. & Lippincott-Schwartz, J. J Cell Biol 1998 Jan 12;140(1):1-15 Europe PMC

Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis. Ellenberg, J., Siggia, E.D., Moreira, J.E., Smith, C.L., Presley, J.F., Worman, H.J. & Lippincott-Schwartz, J. J Cell Biol 1997 Sep 22;138(6):1193-206 Europe PMC

The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulum. Yang, M., Ellenberg, J., Bonifacino, J.S. & Weissman, A.M. J Biol Chem. 1997 Jan 17;272(3):1970-5. Europe PMC

Fluorescence photobleaching techniques. Ellenberg, J. & Lippincott-Schwartz, J. In "Cells: A Laboratory Manual, Vol. 2", Spector, D., Goldman, R. & Leinwand, L. (Eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1997, 79.1-79.23