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Staff at EMBL

CP-60008447

Jean-Karim Hériché

Scientist in Bioinformatics
Ellenberg Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

Total: 25 publication(s)

2014

Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Julia Roberti M, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J. (2014)
Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation
Mol. Biol. Cell doi:10.1091/mbc.E13-04-0221
Europe PMC | doi


2013

Almaça J, Faria D, Sousa M, Uliyakina I, Conrad C, Sirianant L, Clarke LA, Martins JP, Santos M, Heriché JK, Huber W, Schreiber R, Pepperkok R, Kunzelmann K, Amaral MD. (2013)
High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets
Cell 154(6):1390-1400. doi:10.1016/j.cell.2013.08.045
Europe PMC | doi

Petrova B, Dehler S, Kruitwagen T, Hériché JK, Miura K, Haering CH. (2013)
Quantitative analysis of chromosome condensation in fission yeast
Mol. Cell. Biol. 33(5):984-998. doi:10.1128/mcb.01400-12
Europe PMC | doi

Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W. (2013)
Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay
BMC Bioinformatics 14:308. doi:10.1186/1471-2105-14-308
Europe PMC | doi

Ley S, Weigert A, Hériché JK, Mille-Baker B, Janssen RA, Brüne B. (2013)
RNAi screen in apoptotic cancer cell-stimulated human macrophages reveals co-regulation of IL-6/IL-10 expression
Immunobiology 218(1):40-51. doi:10.1016/j.imbio.2012.01.019
Europe PMC | doi


2012

Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grøfte M, Bartkova J, Poulsen M, Oka Y, Bekker-Jensen S, Mailand N, Neumann B, Heriche JK, Shearer R, Saunders D, Bartek J, Lukas J, Lukas C. (2012)
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
Cell 150(4):697-709. doi:10.1016/j.cell.2012.06.039
Europe PMC | doi

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. (2012)
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
Nat. Cell Biol. 14(7):764-774. doi:10.1038/ncb2510
Europe PMC | doi

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J. (2012)
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1
Cell Death Differ. 19(5):798-807. doi:10.1038/cdd.2011.150
Europe PMC | doi

Bird AW, Erler A, Fu J, Hériché JK, Maresca M, Zhang Y, Hyman AA, Stewart AF. (2012)
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes
Nat. Methods 9(1):103-109. doi:10.1038/nmeth.1803
Europe PMC | doi


2011

Lees JG, Heriche JK, Morilla I, Ranea JA, Orengo CA. (2011)
Systematic computational prediction of protein interaction networks
Phys Biol 8(3):035008. doi:10.1088/1478-3975/8/3/035008
Europe PMC | doi

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM. (2011)
Systematic phosphorylation analysis of human mitotic protein complexes
Sci Signal 4(198):rs12. doi:10.1126/scisignal.2001993
Europe PMC | doi


2010

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J. (2010)
Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging
J. Struct. Biol. 170(1):1-9. doi:10.1016/j.jsb.2009.10.004
Europe PMC | doi

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. (2010)
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Nature 464(7289):721-727. doi:10.1038/nature08869
Europe PMC | doi

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. (2010)
Systematic analysis of human protein complexes identifies chromosome segregation proteins
Science 328(5978):593-599. doi:10.1126/science.1181348
Europe PMC | doi

Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Hériché JK. (2010)
Visualization of image data from cells to organisms
Nat. Methods 7(3 Suppl):S26-41. doi:10.1038/nmeth.1431
Europe PMC | doi

O'Donoghue SI, Gavin AC, Gehlenborg N, Goodsell DS, Hériché JK, Nielsen CB, North C, Olson AJ, Procter JB, Shattuck DW, Walter T, Wong B. (2010)
Visualizing biological data-now and in the future
Nat. Methods 7(3 Suppl):S2-4. doi:10.1038/nmeth.f.301
Europe PMC | doi

Smedley D, Schofield P, Chen CK, Aidinis V, Ainali C, Bard J, Balling R, Birney E, Blake A, Bongcam-Rudloff E, Brookes AJ, Cesareni G, Chandras C, Eppig J, Flicek P, Gkoutos G, Greenaway S, Gruenberger M, Hériché JK, Lyall A, Mallon AM, Muddyman D, Reisinger F, Ringwald M, Rosenthal N, Schughart K, Swertz M, Thorisson GA, Zouberakis M, Hancock JM. (2010)
Finding and sharing: new approaches to registries of databases and services for the biomedical sciences
Database (Oxford) 2010:baq014. doi:10.1093/database/baq014
Europe PMC | doi


2008

Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J. (2008)
A genome wide RNAI screen by time lapse microscopy in order to identify mitotic genes - Computational aspects and challenges
I S BIOMED IMAGING 328-331.

Ruan J, Li H, Chen Z, Coghlan A, Coin LJ, Guo Y, Hériché JK, Hu Y, Kristiansen K, Li R, Liu T, Moses A, Qin J, Vang S, Vilella AJ, Ureta-Vidal A, Bolund L, Wang J, Durbin R. (2008)
TreeFam: 2008 Update
Nucleic Acids Res. 36(Database issue):D735-40. doi:10.1093/nar/gkm1005
Europe PMC | doi


2006

Moses AM, Hériché JK, Durbin R. (2006)
Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase.
Genome Biol. 8(2) doi:10.1186/gb-2007-8-2-r23
Europe PMC | doi

Li H, Coghlan A, Ruan J, Coin LJ, Hériché JK, Osmotherly L, Li R, Liu T, Zhang Z, Bolund L, Wong GK, Zheng W, Dehal P, Wang J, Durbin R. (2006)
TreeFam: a curated database of phylogenetic trees of animal gene families.
Nucleic Acids Res. 34(Database issue):D572-80. doi:10.1093/nar/gkj118
Europe PMC | doi


2003

Hériché JK, Ang D, Bier E, O'Farrell PH. (2003)
Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila.
BMC Genet. 4 doi:10.1186/1471-2156-4-9
Europe PMC | doi


1998

Hériché JK, Chambaz EM. (1998)
Protein kinase CK2alpha is a target for the Abl and Bcr-Abl tyrosine kinases.
Oncogene 17(1):13-18. doi:10.1038/sj.onc.1201900
Europe PMC | doi


1997

Leroy D, Heriché JK, Filhol O, Chambaz EM, Cochet C. (1997)
Binding of polyamines to an autonomous domain of the regulatory subunit of protein kinase CK2 induces a conformational change in the holoenzyme. A proposed role for the kinase stimulation.
J. Biol. Chem. 272(33):20820-20827. doi:10.1074/jbc.272.33.20820
Europe PMC | doi

Hériché JK, Lebrin F, Rabilloud T, Leroy D, Chambaz EM, Goldberg Y. (1997)
Regulation of protein phosphatase 2A by direct interaction with casein kinase 2alpha.
Science 276(5314):952-955. doi:10.1126/science.276.5314.952
Europe PMC | doi