Ellenberg GroupCollaborative Projects

MitoCheck: Regulation of mitosis by phosphorylation - a combined functional genomics, proteomics and chemical biology approach

Integrated Project (FP6)

Starting date: 1 April 2004
Duration: 48 months
Total funding: € 8 500 000
Contract no: FP6-503464
Project coordinator: Jan-Michael Peters
Local coordinator: Jan Ellenberg

MitoCheck is an integrated research project which brings together leading European research groups to study systematically the regulation of mitosis in human cells.

MitoCheck is funded within the Sixth Framework of the European Commission for 4 years from the 1st April 2004 and co-ordinated by Dr. Jan-Michael Peters from the Institute of Molecular Pathology [IMP] in Vienna. The full list of participants includes groups from Austria, Germany, Italy, France and the UK.

The project aims to test all human genes for involvement in mitosis by RNAi, then identify a subset which will be studied intensively for changes in phosphorylation, subcellular localization and involvement in protein complexes. Other aspects will look at engineering mitotic kinases and translational opportunities for human health.

Project website