Top image

Staff at EMBL

Markus Hassler

Postdoctoral Fellow
Häring Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

Total: 12 publication(s)

2013

Hondele M, Stuwe T, Hassler M, Halbach F, Bowman A, Zhang ET, Nijmeijer B, Kotthoff C, Rybin V, Amlacher S, Hurt E, Ladurner AG. (2013)
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
Nature 499(7456):111-114. doi:10.1038/nature12242
Europe PMC | doi

Jankevicius G, Hassler M, Golia B, Rybin V, Zacharias M, Timinszky G, Ladurner AG. (2013)
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
Nat. Struct. Mol. Biol. 20(4):508-514. doi:10.1038/nsmb.2523
Europe PMC | doi

Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner AG, Gut H, Gasser SM. (2013)
Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation
EMBO J. 32(3):437-449. doi:10.1038/emboj.2012.343
Europe PMC | doi


2012

Hassler M, Ladurner AG. (2012)
Towards a structural understanding of PARP1 activation and related signalling ADP-ribosyl-transferases
Curr. Opin. Struct. Biol. 22(6):721-729. doi:10.1016/j.sbi.2012.08.005
Europe PMC | doi

Ali AA, Timinszky G, Arribas-Bosacoma R, Kozlowski M, Hassa PO, Hassler M, Ladurner AG, Pearl LH, Oliver AW. (2012)
The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks
Nat. Struct. Mol. Biol. 19(7):685-692. doi:10.1038/nsmb.2335
Europe PMC | doi


2011

Hassler M, Jankevicius G, Ladurner AG. (2011)
PARG: a macrodomain in disguise
Structure 19(10):1351-1353. doi:10.1016/j.str.2011.09.007
Europe PMC | doi

Ehrentraut S, Hassler M, Oppikofer M, Kueng S, Weber JM, Mueller JW, Gasser SM, Ladurner AG, Ehrenhofer-Murray AE. (2011)
Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79
Genes Dev. 25(17):1835-1846. doi:10.1101/gad.17175111
Europe PMC | doi

Murawska M, Hassler M, Renkawitz-Pohl R, Ladurner A, Brehm A. (2011)
Stress-induced PARP activation mediates recruitment of Drosophila Mi-2 to promote heat shock gene expression
PLoS Genet. 7(7):e1002206. doi:10.1371/journal.pgen.1002206
Europe PMC | doi


2007

Hassler M, Singh S, Yue WW, Luczynski M, Lakbir R, Sanchez-Sanchez F, Bader T, Pearl LH, Mittnacht S. (2007)
Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture
Mol. Cell 28(3):371-385. doi:10.1016/j.molcel.2007.08.023
Europe PMC | doi

Yue WW, Hassler M, Roe SM, Thompson-Vale V, Pearl LH. (2007)
Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase
EMBO J. 26(20):4402-4412. doi:10.1038/sj.emboj.7601856
Europe PMC | doi


2003

Berger I, Bieniossek C, Schaffitzel C, Hassler M, Santelli E, Richmond TJ. (2003)
Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2
J. Biol. Chem. 278(20):17625-17635. doi:10.1074/jbc.m301646200
Europe PMC | doi


2001

Hassler M, Richmond TJ. (2001)
The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex
EMBO J. 20(12):3018-3028. doi:10.1093/emboj/20.12.3018
Europe PMC | doi