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Staff at EMBL

CP-60003353

Dr. Marko Kaksonen

Group Leader
Kaksonen Group Joint appointment: Structural and Computational Biology Unit

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Biography

PhD 2002, University of Helsinki, Finland.
Postdoctoral research at the University of California, Berkeley, USA.
Group leader at EMBL since 2006.

Publications

Total: 18 publication(s)

2014

Boeke D, Trautmann S, Meurer M, Wachsmuth M, Godlee C, Knop M, Kaksonen M. (2014)
Quantification of cytosolic interactions identifies Ede1 oligomers as key organizers of endocytosis.
Mol. Syst. Biol. 10(11) doi:10.15252/msb.20145422
Europe PMC | doi

Merrifield CJ, Kaksonen M. (2014)
Endocytic Accessory Factors and Regulation of Clathrin-Mediated Endocytosis.
Cold Spring Harb Perspect Biol doi:10.1101/cshperspect.a016733
Europe PMC | doi

Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, Kaksonen M, Cusack S, Ephrussi A, Pillai RS. (2014)
RNA Clamping by Vasa Assembles a piRNA Amplifier Complex on Transposon Transcripts
Cell 157(7):1698-1711. doi:10.1016/j.cell.2014.05.018
Europe PMC | doi

Brach T, Godlee C, Moeller-Hansen I, Boeke D, Kaksonen M. (2014)
The initiation of clathrin-mediated endocytosis is mechanistically highly flexible
Curr. Biol. 24(5):548-554. doi:10.1016/j.cub.2014.01.048
Europe PMC | doi


2013

Godlee C, Kaksonen M. (2013)
Review series: From uncertain beginnings: initiation mechanisms of clathrin-mediated endocytosis
J. Cell Biol. 203(5):717-725. doi:10.1083/jcb.201307100
Europe PMC | doi

Maeda K, Anand K, Chiapparino A, Kumar A, Poletto M, Kaksonen M, Gavin AC. (2013)
Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins
Nature 501(7466):257-261. doi:10.1038/nature12430
Europe PMC | doi

Gallego O, Specht T, Brach T, Kumar A, Gavin AC, Kaksonen M. (2013)
Detection and characterization of protein interactions in vivo by a simple live-cell imaging method
PLoS ONE 8(5):e62195. doi:10.1371/journal.pone.0062195
Europe PMC | doi


2012

Skruzny M, Brach T, Ciuffa R, Rybina S, Wachsmuth M, Kaksonen M. (2012)
Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis
Proc. Natl. Acad. Sci. U.S.A. 109(38):E2533-42. doi:10.1073/pnas.1207011109
Europe PMC | doi

Kukulski W, Schorb M, Kaksonen M, Briggs JA. (2012)
Plasma membrane reshaping during endocytosis is revealed by time-resolved electron tomography
Cell 150(3):508-520. doi:10.1016/j.cell.2012.05.046
Europe PMC | doi

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. (2012)
Precise, correlated fluorescence microscopy and electron tomography of lowicryl sections using fluorescent fiducial markers
Methods Cell Biol. 111:235-257. doi:10.1016/b978-0-12-416026-2.00013-3
Europe PMC | doi


2011

Brach T, Specht T, Kaksonen M. (2011)
Reassessment of the role of plasma membrane domains in the regulation of vesicular traffic in yeast
J. Cell. Sci. 124(Pt 3):328-337. doi:10.1242/jcs.078519
Europe PMC | doi

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. (2011)
Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision
J. Cell Biol. 192(1):111-119. doi:10.1083/jcb.201009037
Europe PMC | doi


2010

Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC. (2010)
A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae
Mol. Syst. Biol. 6:430. doi:10.1038/msb.2010.87
Europe PMC | doi


2008

Kaksonen M. (2008)
Taking apart the endocytic machinery
J. Cell Biol. 180(6):1059-1060. doi:10.1083/jcb.200802174
Europe PMC | doi


2006

Liu J, Kaksonen M, Drubin DG, Oster G. (2006)
Endocytic vesicle scission by lipid phase boundary forces
Proc. Natl. Acad. Sci. U.S.A. 103(27):10277-10282. doi:10.1073/pnas.0601045103
Europe PMC | doi

Kaksonen M, Toret CP, Drubin DG. (2006)
Harnessing actin dynamics for clathrin-mediated endocytosis
Nat. Rev. Mol. Cell Biol. 7(6):404-414. doi:10.1038/nrm1940
Europe PMC | doi


2005

Kaksonen M, Toret CP, Drubin DG. (2005)
A modular design for the clathrin- and actin-mediated endocytosis machinery
Cell 123(2):305-320. doi:10.1016/j.cell.2005.09.024
Europe PMC | doi


2003

Kaksonen M, Sun Y, Drubin DG. (2003)
A pathway for association of receptors, adaptors, and actin during endocytic internalization
Cell 115(4):475-487. doi:10.1016/s0092-8674(03)00883-3
Europe PMC | doi