Staff at EMBL

Dr. Péter Lénárt

Group Leader
Lénárt Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Biography

PhD 2004, EMBL and University of Heidelberg.
Postdoctoral research at the Institute of Molecular Pathology (IMP), Vienna.
Staff scientist at EMBL Heidelberg since 2008.
Group leader since 2011.

Publications

Bayesian approach to MSD-based analysis of particle motion in live cells. Monnier, N., Guo, S.M., Mori, M., He, J., Lenart, P. & Bathe, M. Biophys J. 2012 Aug 8;103(3):616-26. doi: 10.1016/j.bpj.2012.06.029. PubMed

Bulk cytoplasmic actin and its functions in meiosis and mitosis. Field, C.M. & Lenart, P. Curr Biol. 2011 Oct 11;21(19):R825-30. PubMed

Intracellular transport by an anchored homogeneously contracting F-actin meshwork. Mori, M., Monnier, N., Daigle, N., Bathe, M., Ellenberg, J. & Lenart, P. Curr Biol. 2011 Apr 12;21(7):606-11. PubMed

APPL proteins FRET at the BAR: direct observation of APPL1 and APPL2 BAR domain-mediated interactions on cell membranes using FRET microscopy. Chial, H.J., Lenart, P. & Chen, Y.Q. PLoS One. 2010 Aug 30;5(8):e12471. PubMed

Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Herzog, F., Primorac, I., Dube, P., Lenart, P., Sander, B., Mechtler, K., Stark, H. & Peters, J.M. Science. 2009 Mar 13;323(5920):1477-81. PubMed

Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. Petronczki, M., Lenart, P. & Peters, J.M. Dev Cell. 2008 May;14(5):646-59. PubMed

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. Schmitz, J., Watrin, E., Lenart, P., Mechtler, K. & Peters, J.M. Curr Biol. 2007 Apr 3;17(7):630-6. Epub 2007 Mar 8. PubMed

BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Steegmaier, M., Hoffmann, M., Baum, A., Lenart, P., Petronczki, M., Krssak, M., Gurtler, U., Garin-Chesa, P., Lieb, S., Quant, J., Grauert, M., Adolf, G.R., Kraut, N., Peters, J.M. & Rettig, W.J. Curr Biol. 2007 Feb 20;17(4):316-22. Epub 2007 Feb 8. PubMed

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Lenart, P., Petronczki, M., Steegmaier, M., Di Fiore, B., Lipp, J.J., Hoffmann, M., Rettig, W.J., Kraut, N. & Peters, J.M. Curr Biol. 2007 Feb 20;17(4):304-15. Epub 2007 Feb 8. PubMed

Checkpoint activation: don't get mad too much. Lenart, P. & Peters, J.M. Curr Biol. 2006 Jun 6;16(11):R412-4. PubMed

Monitoring the permeability of the nuclear envelope during the cell cycle. Lenart, P. & Ellenberg, J. Methods 2006 Jan;38(1):17-24. PubMed

A contractile nuclear actin network drives chromosome congression in oocytes. Lenart, P., Bacher, C.P., Daigle, N., Hand, A.R., Eils, R., Terasaki, M. & Ellenberg, J. Nature 2005 Aug 11;436(7052):812-8. Epub 2005 Jul 13. PubMed

Dynamic targeting of microtubules by TPPP/p25 affects cell survival. Lehotzky, A., Tirian, L., Tokesi, N., Lenart, P., Szabo, B., Kovacs, J. & Ovadi, J. J Cell Sci. 2004 Dec 1;117(Pt 25):6249-59. PubMed

Dynamics of nuclear pore complex organization through the cell cycle. Rabut, G., Lenart, P. & Ellenberg, J. Curr Opin Cell Biol 2004 Jun;16(3):314-21. PubMed

Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. Lénart, P., Rabut, G., Daigle, N., Hand, A.R., Terasaki, M. & Ellenberg, J. J Cell Biol 2003 Mar 31;160(7):1055-68. PubMed

Involvement of MAP kinase SIMK and actin cytoskeleton in the regulation of root hair tip growth. Samaj, J., Ovecka, M., Hlavacka, A., Lecourieux, F., Meskiene, I., Lichtscheidl, I., Lenart, P., Salaj, J., Volkmann, D., Bogre, L., Baluska, F. & Hirt, H. Cell Biol Int. 2003;27(3):257-9. PubMed

Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation. Schmitt, A., Gutierrez, G.J., Lenart, P., Ellenberg, J. & Nebreda, A.R. FEBS Lett 2002 May 8;518(1-3):23-8. PubMed