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Staff at EMBL

CP-60003841

Dr. Péter Lénárt

Group Leader
Lénárt Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Biography

PhD 2004, EMBL and University of Heidelberg.
Postdoctoral research at the Institute of Molecular Pathology (IMP), Vienna.
Staff scientist at EMBL Heidelberg since 2008.
Group leader since 2011.

Publications

Total: 21 publication(s)

2014

Mori M, Somogyi K, Kondo H, Monnier N, Falk HJ, Machado P, Bathe M, Nédélec F, Lénárt P. (2014)
An arp2/3 nucleated f-actin shell fragments nuclear membranes at nuclear envelope breakdown in starfish oocytes.
Curr. Biol. 24(12):1421-1428. doi:10.1016/j.cub.2014.05.019
Europe PMC | doi


2012

Monnier N, Guo SM, Mori M, He J, Lénárt P, Bathe M. (2012)
Bayesian approach to MSD-based analysis of particle motion in live cells
Biophys. J. 103(3):616-626. doi:10.1016/j.bpj.2012.06.029
Europe PMC | doi


2011

Field CM, Lénárt P. (2011)
Bulk cytoplasmic actin and its functions in meiosis and mitosis
Curr. Biol. 21(19):R825-30. doi:10.1016/j.cub.2011.07.043
Europe PMC | doi

Mori M, Monnier N, Daigle N, Bathe M, Ellenberg J, Lénárt P. (2011)
Intracellular transport by an anchored homogeneously contracting F-actin meshwork
Curr. Biol. 21(7):606-611. doi:10.1016/j.cub.2011.03.002
Europe PMC | doi

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM. (2011)
Systematic phosphorylation analysis of human mitotic protein complexes
Sci Signal 4(198):rs12. doi:10.1126/scisignal.2001993
Europe PMC | doi


2010

Chial HJ, Lenart P, Chen YQ. (2010)
APPL proteins FRET at the BAR: direct observation of APPL1 and APPL2 BAR domain-mediated interactions on cell membranes using FRET microscopy
PLoS ONE 5(8):e12471. doi:10.1371/journal.pone.0012471
Europe PMC | doi


2009

Herzog F, Primorac I, Dube P, Lenart P, Sander B, Mechtler K, Stark H, Peters JM. (2009)
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex
Science 323(5920):1477-1481. doi:10.1126/science.1163300
Europe PMC | doi


2008

Petronczki M, Lénárt P, Peters JM. (2008)
Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1
Dev. Cell 14(5):646-659. doi:10.1016/j.devcel.2008.04.014
Europe PMC | doi


2007

Schmitz J, Watrin E, Lénárt P, Mechtler K, Peters JM. (2007)
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase
Curr. Biol. 17(7):630-636. doi:10.1016/j.cub.2007.02.029
Europe PMC | doi

Steegmaier M, Hoffmann M, Baum A, Lénárt P, Petronczki M, Krssák M, Gürtler U, Garin-Chesa P, Lieb S, Quant J, Grauert M, Adolf GR, Kraut N, Peters JM, Rettig WJ. (2007)
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo
Curr. Biol. 17(4):316-322. doi:10.1016/j.cub.2006.12.037
Europe PMC | doi

Lénárt P, Petronczki M, Steegmaier M, Di Fiore B, Lipp JJ, Hoffmann M, Rettig WJ, Kraut N, Peters JM. (2007)
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
Curr. Biol. 17(4):304-315. doi:10.1016/j.cub.2006.12.046
Europe PMC | doi


2006

Lénárt P, Peters JM. (2006)
Checkpoint activation: don't get mad too much
Curr. Biol. 16(11):R412-4. doi:10.1016/j.cub.2006.05.008
Europe PMC | doi

Lénárt P, Ellenberg J. (2006)
Monitoring the permeability of the nuclear envelope during the cell cycle
Methods 38(1):17-24. doi:10.1016/j.ymeth.2005.07.010
Europe PMC | doi


2005

Lénárt P, Bacher CP, Daigle N, Hand AR, Eils R, Terasaki M, Ellenberg J. (2005)
A contractile nuclear actin network drives chromosome congression in oocytes
Nature 436(7052):812-818. doi:10.1038/nature03810
Europe PMC | doi


2004

Lehotzky A, Tirián L, Tökési N, Lénárt P, Szabó B, Kovács J, Ovádi J. (2004)
Dynamic targeting of microtubules by TPPP/p25 affects cell survival
J. Cell. Sci. 117(Pt 25):6249-6259. doi:10.1242/jcs.01550
Europe PMC | doi

Rabut G, Lénárt P, Ellenberg J. (2004)
Dynamics of nuclear pore complex organization through the cell cycle
Curr. Opin. Cell Biol. 16(3):314-321. doi:10.1016/j.ceb.2004.04.001
Europe PMC | doi

Strickland L, von Dassow G, Ellenberg J, Foe V, Lenart P, Burgess D. (2004)
Light microscopy of echinoderm embryos
Methods Cell Biol. 74:371-409. doi:10.1016/S0091-679X(04)74016-9
Europe PMC | doi


2003

Lénárt P, Rabut G, Daigle N, Hand AR, Terasaki M, Ellenberg J. (2003)
Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes
J. Cell Biol. 160(7):1055-1068. doi:10.1083/jcb.200211076
Europe PMC | doi

Lénárt P, Ellenberg J. (2003)
Nuclear envelope dynamics in oocytes: from germinal vesicle breakdown to mitosis
Curr. Opin. Cell Biol. 15(1):88-95. doi:10.1016/s0955-0674(02)00011-x
Europe PMC | doi

Samaj J, Ovecka M, Hlavacka A, Lecourieux F, Meskiene I, Lichtscheidl I, Lenart P, Salaj J, Volkmann D, Bögre L, Baluska F, Hirt H. (2003)
Involvement of MAP kinase SIMK and actin cytoskeleton in the regulation of root hair tip growth
Paper presented at the NATO Advanced Research Workshop on Plant Cytoskeleton - Functional Diversity and Biotechnological Implications, KIEV, UKRAINE, SEP 23-27, 2002.Cell Biol. Int. 27(3):257-259. doi:10.1016/s1065-6995(02)00344-x
Europe PMC | doi


2002

Schmitt A, Gutierrez GJ, Lénárt P, Ellenberg J, Nebreda AR. (2002)
Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation
FEBS Lett. 518(1-3):23-28. doi:10.1016/s0014-5793(02)02630-3
Europe PMC | doi