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Staff at EMBL

Mikhail Eltsov

Scientist in Electron Tomography
Cell Biology and Biophysics Electron Microscopy Core Facility

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

ELCS in ice: cryo-electron microscopy of nuclear envelope-limited chromatin sheets. Eltsov, M., Sosnovski, S., Olins, A.L. & Olins, D.E. Chromosoma. 2014 Feb 26. Europe PMC

Facilitated aggregation of FG nucleoporins under molecular crowding conditions. Milles, S., Huy Bui, K., Koehler, C., Eltsov, M., Beck, M. & Lemke, E.A. EMBO Rep. 2013 Feb;14(2):178-83. doi: 10.1038/embor.2012.204. Epub 2012 Dec 14. Europe PMC

Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures. Saibil, H.R., Seybert, A., Habermann, A., Winkler, J., Eltsov, M., Perkovic, M., Castano-Diez, D., Scheffer, M.P., Haselmann, U., Chlanda, P., Lindquist, S., Tyedmers, J. & Frangakis, A.S. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14906-11. doi:10.1073/pnas.1211976109. Epub 2012 Aug 27. Europe PMC

Nucleosomes stacked with aligned dyad axes are found in native compact chromatin in vitro. Scheffer, M.P., Eltsov, M., Bednar, J. & Frangakis, A.S. J Struct Biol. 2012 May;178(2):207-14. Epub 2011 Nov 22. Europe PMC

Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. Nishino, Y., Eltsov, M., Joti, Y., Ito, K., Takata, H., Takahashi, Y., Hihara, S., Frangakis, A.S., Imamoto, N., Ishikawa, T. & Maeshima, K. EMBO J. 2012 Feb 17;31(7):1644-53. doi: 10.1038/emboj.2012.35. Europe PMC

Evidence for short-range helical order in the 30-nm chromatin fibers of erythrocyte nuclei. Scheffer, M.P., Eltsov, M. & Frangakis, A.S. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):16992-7. Epub 2011 Oct 3. Europe PMC

Chromatin structure: does the 30-nm fibre exist in vivo? Maeshima, K., Hihara, S. & Eltsov, M. Curr Opin Cell Biol. 2010 Jun;22(3):291-7. Epub 2010 Mar 24. Europe PMC

Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. Eltsov, M., Maclellan, K.M., Maeshima, K., Frangakis, A.S. & Dubochet, J. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19732-7. doi:10.1073/pnas.0810057105. Epub 2008 Dec 8. Europe PMC

Packaging the genome: the structure of mitotic chromosomes. Maeshima, K. & Eltsov, M. J Biochem. 2008 Feb;143(2):145-53. Epub 2007 Nov 2. Europe PMC

Cemovis Cryo-Electron Microscopy of Vitreous Sections. Dubochet, J., Al-Amoudi, A., Bouchet-Marquis, C., Eltsov, M. & Zuber, B. In Cavalier, A., Humbel, B.M. & Spehner, A. (eds.) Handbook of Cryo-Preparation Methods for Electron Microscopy. CRC press. 2008, 259-289.

Visualization of cell microtubules in their native state. Bouchet-Marquis, C., Zuber, B., Glynn, A.M., Eltsov, M., Grabenbauer, M., Goldie, K.N., Thomas, D., Frangakis, A.S., Dubochet, J. & Chretien, D. Biol Cell. 2007 Jan;99(1):45-53. Europe PMC

How to "read" a vitreous section. Dubochet, J., Zuber, B., Eltsov, M., Bouchet-Marquis, C., Al-Amoudi, A. & Livolant, F. Methods Cell Biol. 2007;79:385-406. Europe PMC

Transmission electron microscopy of the bacterial nucleoid. Eltsov, M. & Zuber, B. J Struct Biol. 2006 Nov;156(2):246-54. Epub 2006 Aug 2. Europe PMC

Study of the Deinococcus radiodurans nucleoid by cryoelectron microscopy of vitreous sections: Supplementary comments. Eltsov, M. & Dubochet, J. J Bacteriol. 2006 Sep;188(17):6053-8; discussion 6059. Europe PMC

Fine structure of the Deinococcus radiodurans nucleoid revealed by cryoelectron microscopy of vitreous sections. Eltsov, M. & Dubochet, J. J Bacteriol. 2005 Dec;187(23):8047-54. Europe PMC

Chromosome structure: improved immunolabeling for electron microscopy. Maeshima, K., Eltsov, M. & Laemmli, U.K. Chromosoma. 2005 Nov;114(5):365-75. Epub 2005 Nov 12. Europe PMC

DNA double-strand breaks induce formation of RP-A/Ku foci on in vitro reconstituted Xenopus sperm nuclei. Grandi, P., Eltsov, M., Nielsen, I. & Raska, I. J Cell Sci. 2001 Sep;114(Pt 18):3345-57. Europe PMC

Ultrastructural characterization of RPA-containing domains in nuclei assembled in Xenopus egg extracts. Eltsov, M., Grandi, P. & Raska, I. J Struct Biol. 2000 Apr;129(2-3):211-7. Europe PMC

Nuclear organization studied with the help of a hypotonic shift: its use permits hydrophilic molecules to enter into living cells. Koberna, K., Stanek, D., Malinsky, J., Eltsov, M., Pliss, A., Ctrnacta, V., Cermanova, S. & Raska, I. Chromosoma. 1999 Sep;108(5):325-35. Europe PMC