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Staff at EMBL

Jelger Lycklama à Nijeholt

Postdoctoral Fellow (EIPOD)
Schaffitzel Team Briggs Group Pepperkok Team

EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France

E-mail: lycklama@embl.fr

Publications

Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC. Schulze, R.J., Komar, J., Botte, M., Allen, W.J., Whitehouse, S., Gold, V.A., Lycklama A Nijeholt, J.A., Huard, K., Berger, I., Schaffitzel, C. & Collinson, I. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4844-9. doi:10.1073/pnas.1315901111. Epub 2014 Feb 18. Europe PMC

Characterization of the supporting role of SecE in protein translocation. Lycklama a Nijeholt, J.A., de Keyzer, J., Prabudiansyah, I. & Driessen, A.J. FEBS Lett. 2013 Sep 17;587(18):3083-8. doi: 10.1016/j.febslet.2013.07.046. Epub2013 Aug 13. Europe PMC

The bacterial Sec-translocase: structure and mechanism. Lycklama A Nijeholt, J.A. & Driessen, A.J. Philos Trans R Soc Lond B Biol Sci. 2012 Apr 19;367(1592):1016-28. doi:10.1098/rstb.2011.0201. Europe PMC

Conformational dynamics of the plug domain of the SecYEG protein-conducting channel. Lycklama a Nijeholt, J.A., Wu, Z.C. & Driessen, A.J. J Biol Chem. 2011 Dec 23;286(51):43881-90. doi: 10.1074/jbc.M111.297507. Epub2011 Oct 27. Europe PMC

Immobilization of the plug domain inside the SecY channel allows unrestricted protein translocation. Lycklama A Nijeholt, J.A., Bulacu, M., Marrink, S.J. & Driessen, A.J. J Biol Chem. 2010 Jul 30;285(31):23747-54. doi: 10.1074/jbc.M110.124636. Epub2010 May 19. Europe PMC