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Staff at EMBL

Melissa Graewert

Postdoctoral Fellow (EIPOD)
Svergun Group Merten Group Schultz Group

EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany

E-mail: send a mail

Publications

Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules. Petoukhov, M.V., Billas, I.M., Takacs, M., Graewert, M.A., Moras, D. & Svergun, D.I. Biochemistry. 2013 Oct 1;52(39):6844-55. doi: 10.1021/bi400731u. Epub 2013 Sep19. Europe PMC

Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS). Graewert, M.A. & Svergun, D.I. Curr Opin Struct Biol. 2013 Jul 5. pii: S0959-440X(13)00110-3. doi:10.1016/j.sbi.2013.06.007. Europe PMC

High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation. Muller, R., Grawert, M.A., Kern, T., Madl, T., Peschek, J., Sattler, M., Groll, M. & Buchner, J. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10183-8. doi:10.1073/pnas.1300547110. Epub 2013 Jun 3. Europe PMC

The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Schmid, A.B., Lagleder, S., Grawert, M.A., Rohl, A., Hagn, F., Wandinger, S.K., Cox, M.B., Demmer, O., Richter, K., Groll, M., Kessler, H. & Buchner, J. EMBO J. 2012 Mar 21;31(6):1506-17. doi: 10.1038/emboj.2011.472. Epub 2012 Jan 6. Europe PMC

Exploiting nature's rich source of proteasome inhibitors as starting points in drug development. Grawert, M.A. & Groll, M. Chem Commun (Camb). 2012 Feb 1;48(10):1364-78. doi: 10.1039/c1cc15273d. Epub 2011Oct 31. Europe PMC

Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Grawert, M.A., Gallastegui, N., Stein, M., Schmidt, B., Kloetzel, P.M., Huber, R. & Groll, M. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. doi: 10.1002/anie.201005488. Europe PMC