Staff at EMBL

Dr. Thomas Walter

Scientific Officer
Ellenberg Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Publications

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. Held, M., Schmitz, M.H., Fischer, B., Walter, T., Neumann, B., Olma, M.H., Peter, M., Ellenberg, J. & Gerlich, D.W. Nat Methods. 2010 Aug 8. PubMed

Evaluation of automated fundus photograph analysis algorithms for detecting microaneurysms, haemorrhages and exudates, and of a computer-assisted diagnostic system for grading diabetic retinopathy. Dupas, B., Walter, T., Erginay, A., Ordonez, R., Deb-Joardar, N., Gain, P., Klein, J.C. & Massin, P. Diabetes Metab. 2010 Jun;36(3):213-20. Epub 2010 Mar 10. PubMed

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Neumann, B., Walter, T., Heriche, J.K., Bulkescher, J., Erfle, H., Conrad, C., Rogers, P., Poser, I., Held, M., Liebel, U., Cetin, C., Sieckmann, F., Pau, G., Kabbe, R., Wünsche, A., Satagopam, V., Schmitz, M.H., Chapuis, C., Gerlich, D.W., Schneider, R., Eils, R., Huber, W., Peters, J.M., Hyman, A.A., Durbin, R., Pepperkok, R. & Ellenberg, J. Nature. 2010 Apr 1;464(7289):721-7. PubMed

Visualization of image data from cells to organisms. Walter, T., Shattuck, D.W., Baldock, R., Bastin, M.E., Carpenter, A.E., Duce, S., Ellenberg, J., Fraser, A., Hamilton, N., Pieper, S., Ragan, M.A., Schneider, J.E., Tomancak, P. & Heriche, J.K. Nat Methods. 2010 Mar;7(3 Suppl):S26-41. PubMed

Visualizing biological data - now and in the future. O'Donoghue, S.I., Gavin, A.C., Gehlenborg, N., Goodsell, D.S., Heriche, J.K., Nielsen, C.B., North, C., Olson, A.J., Procter, J.B., Shattuck, D.W., Walter, T. & Wong, B. Nat Methods. 2010 Mar;7(3 Suppl):S2-4. PubMed

High-Throughput Microscopy Using Live Mammalian Cells. S Terjung, T Walter, A Seitz, B Neumann, R Pepperkok, J Ellenberg. In "Live Cell Imaging: A Laboratory Manual", D Spector, R Goldman, J Swedlow (Eds.), Cold Spring Harbor Laboratory Press, 2010, 297-314

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. Walter, T., Held, M., Neumann, B., Heriche, J.K., Conrad, C., Pepperkok, R. & Ellenberg, J. J Struct Biol. 2009 Oct 23. PubMed

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase. Tegha-Dunghu, J., Neumann, B., Reber, S., Krause, R., Erfle, H., Walter, T., Held, M., Rogers, P., Hupfeld, K., Ruppert, T., Ellenberg, J. & Gruss, O.J. J Cell Sci. 2008 May 15;121(Pt 10):1718-26. Epub 2008 Apr 29. PubMed

Automatic detection of microaneurysms in color fundus images. Walter, T., Massin, P., Erginay, A., Ordonez, R., Jeulin, C. & Klein, J.C. Med Image Anal. 2007 Dec;11(6):555-66. Epub 2007 May 26. PubMed

Anti-angiogenic properties of myo-inositol trispyrophosphate in ovo and growth reduction of implanted glioma. Sihn, G., Walter, T., Klein, J.C., Queguiner, I., Iwao, H., Nicolau, C., Lehn, J.M., Corvol, P. & Gasc, J.M. FEBS Lett. 2007 Mar 6;581(5):962-6. Epub 2007 Feb 14. PubMed

Redistribution of the neurosensory retina in inferior limited macular translocation: an evaluation using image registration. Denion, E., Ordonez, J.R., Klein, J.C., Glacet-Bernard, A., Walter, T. & Caputo, G. Graefes Arch Clin Exp Ophthalmol. 2007 Mar;245(3):437-42. Epub 2006 Aug31. PubMed

Reverse transfection on cell arrays for high content screening microscopy. Erfle, H., Neumann, B., Liebel, U., Rogers, P., Held, M., Walter, T., Ellenberg, J. & Pepperkok, R. Nat Protoc. 2007;2(2):392-9. PubMed