Surrey GroupCollaborative Projects

Marie Curie Research Training Network Understanding the Dynamics of Cell Division

The goal of this Research Training Network is to gain a better understanding of the regulated dynamics of cell division in eukaryotes. We focus on the study of the interplay between regulators (e.g. kinases, phosphatases) of cell division and the mechanical parts of the spindle, mostly molecular motors and other factors modulating microtubule dynamics.

Positions for 9 PhD students and 6 postdocs are fundeded through this network grant.

Coordinator
Thomas Surrey, European Molecular Biology Laboratory, Heidelberg, Germany

Participants
Ariane Abrieu, Centre National de la Recherche Scientifique, Montpellier, France
Athanassios Giannis, Universität Leipzig, Leipzig, Germany
Thomas Mayer, Max-Planck-Institut für Biochemie, München, Germany
Bela Novak, Hungarian Academy of Sciences, Budapest, Hungary
Jon Pines, University of Cambridge, Cambridge, UK
Elmar Schiebel, ZMBH, University of Heidelberg, Germany
Alvaro Tavares, Instituto Gulbenkian de Ciencia, Lisbon, Portugal
Isabelle Vernos, Centre de Regulacio Genomica, Barcelona, Spain

Website: www.uni-leipzig.de/~organik/spindle_dynamics/

STREP Active Biomimetic Systems

Active Biomimetic Systems involve two types of biomolecular nanomachines, growing filaments and stepping motors, which are able to generate force in the nanodomain. This research network will elucidate the molecular mechanism underlying this force generation and will explore new possibilities for the integration of these molec ular machines into nano- and microsystems.

Coordinator
Reinhard Lipowsky, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany

Participants Marie-France Carlier, Laboratoire d'Enzymologie et Biochimie Structurales, Gif-sur-Yvette, France Marileen Dogterom, FOM-AMOLF, Amsterdam, Holland Jean-François Joanny, Institute Curie, Paris, France Josef Kaes, University of Leipzig, Leipzig, Germany Simon Nord, BASF, Ludwigshafen, Germany Alberto Redaelli, Politecnico of Milano, Milano, Italy Thomas Surrey and François Nédélec, European Molecular Biology Laboratory, Heidelberg, Germany Eberhard Unger, Institute of Molecular Biotechnology, Jena, Germany

Website: www.active-biomics.org

BMBF Network Directed transport of nanoscopic cargoes along molecular conveyor belts

The goal of this project is to control the design tracks for motor protein driven transport of cargos at the nano- to microscale by combining nanopatterning of surfaces and regulated protein immobilisation techniques.

Coordinator
Jacob Piehler, University of Frankfurt, Germany

Participants
Robert Tampe, University of Frankfurt, Germany
Thomas Surrey, EMBL Heidelberg, Germany
Joachim Spatz, MPI for Metal Research, Stuttgart, Germany
Lütke Notarp, NB Technologies, Bremen, Germany