Staff at EMBL
Dr. Alexander Aulehla
Group Leader
EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
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Biography
MD 2002, Albert-Ludwigs-University, Freiburg.
Research at the MD Anderson Cancer Center, Houston, USA and the MPI, Freiburg.
PhD 2008, Paris VI University.
Postdoctoral research at the Stowers Institute, Kansas City, USA.
Group leader at EMBL since 2009.
Publications
Scaling of embryonic patterning based on phase-gradient encoding. Lauschke, V.M., Tsiairis, C.D., Francois, P. & Aulehla, A. Nature. 2013 Jan 3;493(7430):101-5. doi: 10.1038/nature11804. Epub 2012 Dec 19. PubMed
Oscillating signaling pathways during embryonic development. Aulehla, A. & Pourquie, O. Curr Opin Cell Biol. 2008 Dec;20(6):632-7. Epub 2008 Oct 23. PubMed
A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Aulehla, A., Wiegraebe, W., Baubet, V., Wahl, M.B., Deng, C., Taketo, M., Lewandoski, M. & Pourquie, O. Nat Cell Biol. 2008 Feb;10(2):186-93. Epub 2007 Dec 23. PubMed
On periodicity and directionality of somitogenesis. Aulehla, A. & Pourquie, O. Anat Embryol (Berl). 2006 Dec;211 Suppl 1:3-8. Epub 2006 Sep 21. PubMed
WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Hofmann, M., Schuster-Gossler, K., Watabe-Rudolph, M., Aulehla, A., Herrmann, B.G. & Gossler, A. Genes Dev. 2004 Nov 15;18(22):2712-7. PubMed
Segmentation in vertebrates: clock and gradient finally joined. Aulehla, A. & Herrmann, B.G. Genes Dev. 2004 Sep 1;18(17):2060-7. PubMed
Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Aulehla, A., Wehrle, C., Brand-Saberi, B., Kemler, R., Gossler, A., Kanzler, B. & Herrmann, B.G. Dev Cell. 2003 Mar;4(3):395-406. PubMed
Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation. Aulehla, A. & Johnson, R.L. Dev Biol. 1999 Mar 1;207(1):49-61. PubMed
lunatic fringe is an essential mediator of somite segmentation and patterning. Evrard, Y.A., Lun, Y., Aulehla, A., Gan, L. & Johnson, R.L. Nature. 1998 Jul 23;394(6691):377-81. PubMed
Multiple calvarial defects in lmx1b mutant mice. Chen, H., Ovchinnikov, D., Pressman, C.L., Aulehla, A., Lun, Y. & Johnson, R.L. Dev Genet. 1998;22(4):314-20. PubMed