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Staff at EMBL

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Publications

Total: 23 publication(s)

2014

Strein C, Alleaume AM, Rothbauer U, Hentze MW, Castello A. (2014)
A versatile assay for RNA-binding proteins in living cells
RNA 20(5):721-731. doi:10.1261/rna.043562.113
Europe PMC | doi


2013

Kwon SC, Yi H, Eichelbaum K, Föhr S, Fischer B, You KT, Castello A, Krijgsveld J, Hentze MW, Kim VN. (2013)
The RNA-binding protein repertoire of embryonic stem cells
Nat. Struct. Mol. Biol. 20(9):1122-1130. doi:10.1038/nsmb.2638
Europe PMC | doi

Castello A, Fischer B, Hentze MW, Preiss T. (2013)
RNA-binding proteins in Mendelian disease
Trends Genet. 29(5):318-327. doi:10.1016/j.tig.2013.01.004
Europe PMC | doi

Sánchez EG, Quintas A, Nogal M, Castelló A, Revilla Y. (2013)
African swine fever virus controls the host transcription and cellular machinery of protein synthesis
Virus Res. 173(1):58-75. doi:10.1016/j.virusres.2012.10.025
Europe PMC | doi

Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. (2013)
System-wide identification of RNA-binding proteins by interactome capture
Nat Protoc 8(3):491-500. doi:10.1038/nprot.2013.020
Europe PMC | doi

Álvarez E, Castelló A, Carrasco L, Izquierdo JM. (2013)
Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing
PLoS ONE 8(9):e73723. doi:10.1371/journal.pone.0073723
Europe PMC | doi


2012

Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW. (2012)
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
Cell 149(6):1393-1406. doi:10.1016/j.cell.2012.04.031
Europe PMC | doi

Buzon MJ, Erkizia I, Pou C, Minuesa G, Puertas MC, Esteve A, Castello A, Santos JR, Prado JG, Izquierdo-Useros N, Pattery T, Van Houtte M, Carrasco L, Clotet B, Ruiz L, Martinez-Picado J. (2012)
A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors
J. Antimicrob. Chemother. 67(1):32-38. doi:10.1093/jac/dkr433
Europe PMC | doi

del Pino J, Jiménez JL, Ventoso I, Castelló A, Muñoz-Fernández MÁ, de Haro C, Berlanga JJ. (2012)
GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection
PLoS ONE 7(10):e47272. doi:10.1371/journal.pone.0047272
Europe PMC | doi


2011

Álvarez E, Castelló A, Carrasco L, Izquierdo JM. (2011)
Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease
Biochem. Biophys. Res. Commun. 414(1):142-147. doi:10.1016/j.bbrc.2011.09.040
Europe PMC | doi

Yángüez E, Castello A, Welnowska E, Carrasco L, Goodfellow I, Nieto A. (2011)
Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation
Virology 413(1):93-102. doi:10.1016/j.virol.2011.02.012
Europe PMC | doi

Castelló A, Alvarez E, Carrasco L. (2011)
The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases
J. Biomed. Biotechnol. 2011:369648. doi:10.1155/2011/369648
Europe PMC | doi


2009

Welnowska E, Castelló A, Moral P, Carrasco L. (2009)
Translation of mRNAs from vesicular stomatitis virus and vaccinia virus is differentially blocked in cells with depletion of eIF4GI and/or eIF4GII
J. Mol. Biol. 394(3):506-521. doi:10.1016/j.jmb.2009.09.036
Europe PMC | doi

Castelló A, Izquierdo JM, Welnowska E, Carrasco L. (2009)
RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage
J. Cell. Sci. 122(Pt 20):3799-3809. doi:10.1242/jcs.055988
Europe PMC | doi

Castelló A, Quintas A, Sánchez EG, Sabina P, Nogal M, Carrasco L, Revilla Y. (2009)
Regulation of host translational machinery by African swine fever virus
PLoS Pathog. 5(8):e1000562. doi:10.1371/journal.ppat.1000562
Europe PMC | doi

Sanz MA, Castelló A, Ventoso I, Berlanga JJ, Carrasco L. (2009)
Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells
PLoS ONE 4(3):e4772. doi:10.1371/journal.pone.0004772
Europe PMC | doi

Castelló A, Franco D, Moral-López P, Berlanga JJ, Alvarez E, Wimmer E, Carrasco L. (2009)
HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage
PLoS ONE 4(11):e7997. doi:10.1371/journal.pone.0007997
Europe PMC | doi


2008

Madan V, Castelló A, Carrasco L. (2008)
Viroporins from RNA viruses induce caspase-dependent apoptosis
Cell. Microbiol. 10(2):437-451. doi:10.1111/j.1462-5822.2007.01057.x
Europe PMC | doi


2007

Molina S, Sanz MA, Madan V, Ventoso I, Castelló A, Carrasco L. (2007)
Differential inhibition of cellular and Sindbis virus translation by brefeldin A
Virology 363(2):430-436. doi:10.1016/j.virol.2007.02.001
Europe PMC | doi

Sanz MA, Castelló A, Carrasco L. (2007)
Viral translation is coupled to transcription in Sindbis virus-infected cells
J. Virol. 81(13):7061-7068. doi:10.1128/jvi.02529-06
Europe PMC | doi


2006

Castelló A, Alvarez E, Carrasco L. (2006)
Differential cleavage of eIF4GI and eIF4GII in mammalian cells. Effects on translation
J. Biol. Chem. 281(44):33206-33216. doi:10.1074/jbc.m604340200
Europe PMC | doi

Alvarez E, Castelló A, Menéndez-Arias L, Carrasco L. (2006)
HIV protease cleaves poly(A)-binding protein
Biochem. J. 396(2):219-226. doi:10.1042/bj20060108
Europe PMC | doi

Castelló A, Sanz MA, Molina S, Carrasco L. (2006)
Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G
J. Mol. Biol. 355(5):942-956. doi:10.1016/j.jmb.2005.11.024
Europe PMC | doi