Staff at EMBL
Aurelien Deniaud
Postdoctoral Fellow (EIPOD)
Schaffitzel Team
Cusack Group
Hentze Group
EMBL Grenoble, BP 181, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France
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Publications
Lactococcus lactis, an alternative system for functional expression of peripheral and intrinsic Arabidopsis membrane proteins. Frelet-Barrand, A., Boutigny, S., Moyet, L., Deniaud, A., Seigneurin-Berny, D., Salvi, D., Bernaudat, F., Richaud, P., Pebay-Peyroula, E., Joyard, J. & Rolland, N. PLoS One. 2010 Jan 20;5(1):e8746. PubMed
The respiratory-dependent assembly of ANT1 differentially regulates Bax and Ca2+ mediated cytochrome c release. Faustin, B., Rossignol, R., Deniaud, A., Rocher, C., Claverol, S., Malgat, M., Brenner, C. and Letellier, T. Frontiers Biosc. 2010; in press
Crystallography of membrane proteins: from crystallization to structure. Deniaud, A., Moiseeva, E., Gordeliy, V., Pebay-Peyroula, E. Methods Mol Biol 2010, in press
Role of the permeability transition pore complex in lethal inter-organelle crosstalk. Sharaf El Dein, O., Gallerne, C., Deniaud, A., Brenner, C. & Lemaire, C. Front Biosci. 2009 Jan 1;14:3465-82. PubMed
Differences between CusA and AcrB crystallisation highlighted by protein flexibility. Deniaud, A., Goulielmakis, A., Coves, J. & Pebay-Peyroula, E. PLoS One. 2009 Jul 10;4(7):e6214. PubMed
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Deniaud, A., Sharaf el dein, O., Maillier, E., Poncet, D., Kroemer, G., Lemaire, C. & Brenner, C. Oncogene. 2008 Jan 10;27(3):285-99. Epub 2007 Aug 13. PubMed
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Tarze, A., Deniaud, A., Le Bras, M., Maillier, E., Molle, D., Larochette, N., Zamzami, N., Jan, G., Kroemer, G. & Brenner, C. Oncogene. 2007 Apr 19;26(18):2606-20. Epub 2006 Oct 30. PubMed
Voltage-dependent anion channel transports calcium ions through biomimetic membranes. Deniaud, A., Rossi, C., Berquand, A., Homand, J., Campagna, S., Knoll, W., Brenner, C. & Chopineau, J. Langmuir. 2007 Mar 27;23(7):3898-905. Epub 2007 Feb 22. PubMed
Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells. Borgne-Sanchez, A., Dupont, S., Langonne, A., Baux, L., Lecoeur, H., Chauvier, D., Lassalle, M., Deas, O., Briere, J.J., Brabant, M., Roux, P., Pechoux, C., Briand, J.P., Hoebeke, J., Deniaud, A., Brenner, C., Rustin, P., Edelman, L., Rebouillat, D. & Jacotot, E. Cell Death Differ. 2007 Mar;14(3):422-35. Epub 2006 Aug 4. PubMed
Chemosensitization by knockdown of adenine nucleotide translocase-2. Le Bras, M., Borgne-Sanchez, A., Touat, Z., El Dein, O.S., Deniaud, A., Maillier, E., Lecellier, G., Rebouillat, D., Lemaire, C., Kroemer, G., Jacotot, E. & Brenner, C. Cancer Res. 2006 Sep 15;66(18):9143-52. PubMed
Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis. Sourdeval, M., Lemaire, C., Deniaud, A., Taysse, L., Daulon, S., Breton, P., Brenner, C., Boisvieux-Ulrich, E. & Marano, F. Apoptosis. 2006 Sep;11(9):1545-59. PubMed
Therapeutic peptides: Targeting the mitochondrion to modulate apoptosis. Jacotot, E., Deniaud, A., Borgne-Sanchez, A., Touat, Z., Briand, J.P., Le Bras, M. & Brenner, C. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1312-23. Epub 2006 Jul 14. PubMed
Peptido-targeting of the mitochondrial transition pore complex for therapeutic apoptosis induction. Deniaud, A., Hoebeke, J., Briand, J.P., Muller, S., Jacotot, E. & Brenner, C. Curr Pharm Des. 2006;12(34):4501-11. PubMed
Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. Weaver, J.G., Tarze, A., Moffat, T.C., Lebras, M., Deniaud, A., Brenner, C., Bren, G.D., Morin, M.Y., Phenix, B.N., Dong, L., Jiang, S.X., Sim, V.L., Zurakowski, B., Lallier, J., Hardin, H., Wettstein, P., van Heeswijk, R.P., Douen, A., Kroemer, R.T., Hou, S.T., Bennett, S.A., Lynch, D.H., Kroemer, G. & Badley, A.D. J Clin Invest. 2005 Jul;115(7):1828-38. PubMed
Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells. Nassif, A., Bensussan, A., Boumsell, L., Deniaud, A., Moslehi, H., Wolkenstein, P., Bagot, M. & Roujeau, J.C. J Allergy Clin Immunol. 2004 Nov;114(5):1209-15. PubMed
Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis. Verrier, F., Deniaud, A., Lebras, M., Metivier, D., Kroemer, G., Mignotte, B., Jan, G. & Brenner, C. Oncogene. 2004 Oct 21;23(49):8049-64. PubMed
Mitochondrial membrane permeabilization by HIV-1 Vpr. Deniaud, A., Brenner, C. & Kroemer, G. Mitochondrion. 2004 Jul;4(2-3):223-33. PubMed
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. Boya, P., Morales, M.C., Gonzalez-Polo, R.A., Andreau, K., Gourdier, I., Perfettini, J.L., Larochette, N., Deniaud, A., Baran-Marszak, F., Fagard, R., Feuillard, J., Asumendi, A., Raphael, M., Pau, B., Brenner, C. & Kroemer, G. Oncogene. 2003 Sep 18;22(40):6220-30. PubMed