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Staff at EMBL

CP-60012701

Joachim Weischenfeldt

Postdoctoral Fellow
Korbel Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

Total: 11 publication(s)

2014

Brocks D, Assenov Y, Minner S, Bogatyrova O, Simon R, Koop C, Oakes C, Zucknick M, Lipka DB, Weischenfeldt J, Feuerbach L, Cowper-Sal Lari R, Lupien M, Brors B, Korbel J, Schlomm T, Tanay A, Sauter G, Gerhäuser C, Plass C. (2014)
Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer
Cell Rep 8(3):798-806. doi:10.1016/j.celrep.2014.06.053
Europe PMC | doi

Steurer S, Mayer PS, Adam M, Krohn A, Koop C, Ospina-Klinck D, Tehrani AA, Simon R, Tennstedt P, Graefen M, Wittmer C, Brors B, Plass C, Korbel J, Weischenfeldt J, Sauter G, Huland H, Tsourlakis MC, Minner S, Schlomm T. (2014)
TMPRSS2-ERG Fusions Are Strongly Linked to Young Patient Age in Low-grade Prostate Cancer
Eur. Urol. doi:10.1016/j.eururo.2014.06.027
Europe PMC | doi


2013

Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, Wuttig D, Warnatz HJ, Stehr H, Rausch T, Jäger N, Gu L, Bogatyrova O, Stütz AM, Claus R, Eils J, Eils R, Gerhäuser C, Huang PH, Hutter B, Kabbe R, Lawerenz C, Radomski S, Bartholomae CC, Fälth M, Gade S, Schmidt M, Amschler N, Haß T, Galal R, Gjoni J, Kuner R, Baer C, Masser S, von Kalle C, Zichner T, Benes V, Raeder B, Mader M, Amstislavskiy V, Avci M, Lehrach H, Parkhomchuk D, Sultan M, Burkhardt L, Graefen M, Huland H, Kluth M, Krohn A, Sirma H, Stumm L, Steurer S, Grupp K, Sültmann H, Sauter G, Plass C, Brors B, Yaspo ML, Korbel JO, Schlomm T. (2013)
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer
Cancer Cell 23(2):159-170. doi:10.1016/j.ccr.2013.01.002
Europe PMC | doi

Weischenfeldt J, Symmons O, Spitz F, Korbel JO. (2013)
Phenotypic impact of genomic structural variation: insights from and for human disease
Nat. Rev. Genet. 14(2):125-138. doi:10.1038/nrg3373
Europe PMC | doi


2012

Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P. (2012)
Dissecting the genomic complexity underlying medulloblastoma
Nature 488(7409):100-105. doi:10.1038/nature11284
Europe PMC | doi

Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, Jäger N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, Bender S, Pleier S, Cin H, Hawkins C, Beck C, von Deimling A, Hans V, Brors B, Eils R, Scheurlen W, Blake J, Benes V, Kulozik AE, Witt O, Martin D, Zhang C, Porat R, Merino DM, Wasserman J, Jabado N, Fontebasso A, Bullinger L, Rücker FG, Döhner K, Döhner H, Koster J, Molenaar JJ, Versteeg R, Kool M, Tabori U, Malkin D, Korshunov A, Taylor MD, Lichter P, Pfister SM, Korbel JO. (2012)
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
Cell 148(1-2):59-71. doi:10.1016/j.cell.2011.12.013
Europe PMC | doi

Weischenfeldt J, Waage J, Tian G, Zhao J, Damgaard I, Jakobsen JS, Kristiansen K, Krogh A, Wang J, Porse BT. (2012)
Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Genome Biol. 13(5):R35. doi:10.1186/gb-2012-13-5-r35
Europe PMC | doi


2010

Thoren LA, Nørgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergström FC, Blom AM, Borup R, Bisgaard HC, Porse BT. (2010)
UPF2 is a critical regulator of liver development, function and regeneration
PLoS ONE 5(7):e11650. doi:10.1371/journal.pone.0011650
Europe PMC | doi


2008

Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Mönch K, Thoren LA, Nielsen FC, Jacobsen SE, Nerlov C, Porse BT. (2008)
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
Genes Dev. 22(10):1381-1396. doi:10.1101/gad.468808
Europe PMC | doi


2005

Weischenfeldt J, Lykke-Andersen J, Porse B. (2005)
Messenger RNA surveillance: neutralizing natural nonsense
Curr. Biol. 15(14):R559-62. doi:10.1016/j.cub.2005.07.002
Europe PMC | doi


2004

Doherty TM, Olsen AW, Weischenfeldt J, Huygen K, D'Souza S, Kondratieva TK, Yeremeev VV, Apt AS, Raupach B, Grode L, Kaufmann S, Andersen P. (2004)
Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis
J. Infect. Dis. 190(12):2146-2153. doi:10.1086/425931
Europe PMC | doi