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Staff at EMBL

Joachim Weischenfeldt

Postdoctoral Fellow
Korbel Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

TMPRSS2-ERG Fusions Are Strongly Linked to Young Patient Age in Low-grade Prostate Cancer. Steurer, S., Mayer, P.S., Adam, M., Krohn, A., Koop, C., Ospina-Klinck, D., Tehrani, A.A., Simon, R., Tennstedt, P., Graefen, M., Wittmer, C., Brors, B., Plass, C., Korbel, J., Weischenfeldt, J., Sauter, G., Huland, H., Tsourlakis, M.C., Minner, S. & Schlomm, T. Eur Urol. 2014 Jul 8. pii: S0302-2838(14)00601-0. doi:10.1016/j.eururo.2014.06.027. Europe PMC

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Weischenfeldt, J., Simon, R., Feuerbach, L., Schlangen, K., Weichenhan, D., Minner, S., Wuttig, D., Warnatz, H.J., Stehr, H., Rausch, T., Jager, N., Gu, L., Bogatyrova, O., Stutz, A.M., Claus, R., Eils, J., Eils, R., Gerhauser, C., Huang, P.H., Hutter, B., Kabbe, R., Lawerenz, C., Radomski, S., Bartholomae, C.C., Falth, M., Gade, S., Schmidt, M., Amschler, N., Hass, T., Galal, R., Gjoni, J., Kuner, R., Baer, C., Masser, S., von Kalle, C., Zichner, T., Benes, V., Raeder, B., Mader, M., Amstislavskiy, V., Avci, M., Lehrach, H., Parkhomchuk, D., Sultan, M., Burkhardt, L., Graefen, M., Huland, H., Kluth, M., Krohn, A., Sirma, H., Stumm, L., Steurer, S., Grupp, K., Sultmann, H., Sauter, G., Plass, C., Brors, B., Yaspo, M.L., Korbel, J.O. & Schlomm, T. Cancer Cell. 2013 Feb 11;23(2):159-70. doi: 10.1016/j.ccr.2013.01.002. Europe PMC

Phenotypic impact of genomic structural variation: insights from and for human disease. Weischenfeldt, J., Symmons, O., Spitz, F. & Korbel, J.O. Nat Rev Genet. 2013 Feb;14(2):125-38. doi: 10.1038/nrg3373. Europe PMC

Dissecting the genomic complexity underlying medulloblastoma. Jones, D.T., Jager, N., Kool, M., Zichner, T., Hutter, B., Sultan, M., Cho, Y.J., Pugh, T.J., Hovestadt, V., Stutz, A.M., Rausch, T., Warnatz, H.J., Ryzhova, M., Bender, S., Sturm, D., Pleier, S., Cin, H., Pfaff, E., Sieber, L., Wittmann, A., Remke, M., Witt, H., Hutter, S., Tzaridis, T., Weischenfeldt, J., Raeder, B., Avci, M., Amstislavskiy, V., Zapatka, M., Weber, U.D., Wang, Q., Lasitschka, B., Bartholomae, C.C., Schmidt, M., von Kalle, C., Ast, V., Lawerenz, C., Eils, J., Kabbe, R., Benes, V., van Sluis, P., Koster, J., Volckmann, R., Shih, D., Betts, M.J., Russell, R.B., Coco, S., Tonini, G.P., Schuller, U., Hans, V., Graf, N., Kim, Y.J., Monoranu, C., Roggendorf, W., Unterberg, A., Herold-Mende, C., Milde, T., Kulozik, A.E., von Deimling, A., Witt, O., Maass, E., Rossler, J., Ebinger, M., Schuhmann, M.U., Fruhwald, M.C., Hasselblatt, M., Jabado, N., Rutkowski, S., von Bueren, A.O., Williamson, D., Clifford, S.C., McCabe, M.G., Collins, V.P., Wolf, S., Wiemann, S., Lehrach, H., Brors, B., Scheurlen, W., Felsberg, J., Reifenberger, G., Northcott, P.A., Taylor, M.D., Meyerson, M., Pomeroy, S.L., Yaspo, M.L., Korbel, J.O., Korshunov, A., Eils, R., Pfister, S.M. & Lichter, P. Nature. 2012 Aug 2;488(7409):100-5. doi: 10.1038/nature11284. Europe PMC

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations. Rausch, T., Jones, D.T., Zapatka, M., Stutz, A.M., Zichner, T., Weischenfeldt, J., Jager, N., Remke, M., Shih, D., Northcott, P.A., Pfaff, E., Tica, J., Wang, Q., Massimi, L., Witt, H., Bender, S., Pleier, S., Cin, H., Hawkins, C., Beck, C., von Deimling, A., Hans, V., Brors, B., Eils, R., Scheurlen, W., Blake, J., Benes, V., Kulozik, A.E., Witt, O., Martin, D., Zhang, C., Porat, R., Merino, D.M., Wasserman, J., Jabado, N., Fontebasso, A., Bullinger, L., Rucker, F.G., Dohner, K., Dohner, H., Koster, J., Molenaar, J.J., Versteeg, R., Kool, M., Tabori, U., Malkin, D., Korshunov, A., Taylor, M.D., Lichter, P., Pfister, S.M. & Korbel, J.O. Cell. 2012 Jan 20;148(1-2):59-71. Europe PMC

Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns. Weischenfeldt, J., Waage, J., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J.S., Kristiansen, K., Krogh, A., Wang, J. & Porse, B.T. Genome Biol. 2012 May 24;13(5):R35. doi: 10.1186/gb-2012-13-5-r35. Europe PMC

UPF2 is a critical regulator of liver development, function and regeneration. Thoren, L.A., Norgaard, G.A., Weischenfeldt, J., Waage, J., Jakobsen, J.S., Damgaard, I., Bergstrom, F.C., Blom, A.M., Borup, R., Bisgaard, H.C. & Porse, B.T. PLoS One. 2010 Jul 19;5(7):e11650. doi: 10.1371/journal.pone.0011650. Europe PMC

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Weischenfeldt, J., Damgaard, I., Bryder, D., Theilgaard-Monch, K., Thoren, L.A., Nielsen, F.C., Jacobsen, S.E., Nerlov, C. & Porse, B.T. Genes Dev. 2008 May 15;22(10):1381-96. Europe PMC

Messenger RNA surveillance: neutralizing natural nonsense. Weischenfeldt, J., Lykke-Andersen, J. & Porse, B. Curr Biol. 2005 Jul 26;15(14):R559-62. Europe PMC

Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis. Doherty, T.M., Olsen, A.W., Weischenfeldt, J., Huygen, K., D'Souza, S., Kondratieva, T.K., Yeremeev, V.V., Apt, A.S., Raupach, B., Grode, L., Kaufmann, S. & Andersen, P. J Infect Dis. 2004 Dec 15;190(12):2146-53. Epub 2004 Nov 8. Europe PMC