EMBL Hamburg c/o DESY, Notkestraße 85, 22607 Hamburg, Germany

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Publications

Total: 9 publication(s)

2015

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI. (2015)

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Sci Rep 5 doi:10.1038/srep10734
Europe PMC | doi

Blanchet CE, Spilotros A, Schwemmer F, Graewert MA, Kikhney A, Jeffries CM, Franke D, Mark D, Zengerle R, Cipriani F, Fiedler S, Roessle M, Svergun DI. (2015)

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY).

J Appl Crystallogr 48(Pt 2):431-443. doi:10.1107/s160057671500254x
Europe PMC | doi


2014

Berthelmann A, Lach J, Gräwert MA, Groll M, Eichler J. (2014)

Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer

Org. Biomol. Chem. 12(16):2606-2614. doi:10.1039/c3ob42251h
Europe PMC | doi


2013

Graewert MA, Svergun DI. (2013)

Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS)

Curr. Opin. Struct. Biol. 23(5):748-754. doi:10.1016/j.sbi.2013.06.007
Europe PMC | doi

Petoukhov MV, Billas IM, Takacs M, Graewert MA, Moras D, Svergun DI. (2013)

Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules

Biochemistry 52(39):6844-6855. doi:10.1021/bi400731u
Europe PMC | doi

Müller R, Gräwert MA, Kern T, Madl T, Peschek J, Sattler M, Groll M, Buchner J. (2013)

High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation

Proc. Natl. Acad. Sci. U.S.A. 110(25):10183-10188. doi:10.1073/pnas.1300547110
Europe PMC | doi


2012

Schmid AB, Lagleder S, Gräwert MA, Röhl A, Hagn F, Wandinger SK, Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J. (2012)

The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop

EMBO J. 31(6):1506-1517. doi:10.1038/emboj.2011.472
Europe PMC | doi

Gräwert MA, Groll M. (2012)

Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

Chem. Commun. (Camb.) 48(10):1364-1378. doi:10.1039/c1cc15273d
Europe PMC | doi


2011

Gräwert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. (2011)

Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition

Angew. Chem. Int. Ed. Engl. 50(2):542-544. doi:10.1002/anie.201005488
Europe PMC | doi