Merten GroupPublications
Micro segmented-flow in biochemical and cell-based assays.
Clausell-Tormos, J. & Merten, C.A.
Front Biosci (Elite Ed). 2012 Jan 1;4:1768-79. PubMed
A competitive co-cultivation assay for cancer drug specificity evaluation.
El Debs, B.W., Tschulena, U., Griffiths, A.D. & Merten, C.A.
J Biomol Screen. 2011 Sep;16(8):818-24. Epub 2011 Jul 25. PubMed
Microfluidic devices for diagnostic applications.
Eicher, D. & Merten, C.A.
Expert Rev Mol Diagn. 2011 Jun;11(5):505-19. doi: 10.1586/ERM.11.25. PubMed
Retroviral display in gene therapy, protein engineering, and vaccine development.
Urban, J.H. & Merten, C.A.
ACS Chem Biol. 2011 Jan 21;6(1):61-74. Epub 2010 Dec 20. PubMed
Miniaturization and Parallelization of Biological and Chemical Assays in Microfluidic Devices.
Vyawahare, S., Griffiths, A.D. & Merten, C.A.
Chem Biol. 2010 Oct 29;17(10):1052-65. PubMed
Screening Europe 2010: an update about the latest technologies and applications in high-throughput screening.
Merten, C.A.
Expert Rev Mol Diagn. 2010 Jul;10(5):559-63. PubMed
An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries.
Clausell-Tormos, J., Griffiths, A.D. & Merten, C.A.
Lab Chip. 2010 May 21;10(10):1302-7. Epub 2010 Mar 3. PubMed
Coupling the inhibition of viral transduction with a positive fluorescence signal.
Clausell-Tormos, J., Griffiths, A.D. & Merten, C.A.
Comb Chem High Throughput Screen. 2010 May;13(4):352-7. PubMed
Nanoliter plates--versatile tools for the screening of split-and-mix libraries on-bead and off-bead.
Upert, G., Merten, C.A. & Wennemers, H.
Chem Commun (Camb). 2010 Apr 7;46(13):2209-11. Epub 2010 Feb 23. PubMed
High-throughput screening of enzymes by retroviral display using droplet-based microfluidics.
Granieri, L., Baret, J.C., Griffiths, A.D. & Merten, C.A.
Chem Biol. 2010 Mar 26;17(3):229-35. PubMed
A competition-based assay for the screening of species-specific antibiotics.
Granieri, L., Miller, O.J., Griffiths, A.D. & Merten, C.A.
J Antimicrob Chemother. 2009 Jul;64(1):62-8. Epub 2009 Apr 28. PubMed
Droplets and emulsions: very high-throughput screening in biology
Baret, J.C., Taly, V., Ryckelynck, M., Merten, C.A. & Griffiths, A.D.
Med Sci (Paris). 2009 Jun-Jul;25(6-7):627-32. PubMed
Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes.
Pianowski, Z., Gorska, K., Oswald, L., Merten, C.A. & Winssinger, N.
J Am Chem Soc. 2009 May 13;131(18):6492-7. PubMed
Drop-based microfluidic devices for encapsulation of single cells.
Koster, S., Angile, F.E., Duan, H., Agresti, J.J., Wintner, A., Schmitz, C., Rowat, A.C., Merten, C.A., Pisignano, D., Griffiths, A.D. & Weitz, D.A.
Lab Chip. 2008 Jul;8(7):1110-5. Epub 2008 May 23. PubMed
Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms.
Clausell-Tormos, J., Lieber, D., Baret, J.C., El-Harrak, A., Miller, O.J., Frenz, L., Blouwolff, J., Humphry, K.J., Koster, S., Duan, H., Holtze, C., Weitz, D.A., Griffiths, A.D. & Merten, C.A.
Chem Biol. 2008 May;15(5):427-37. Research Highlight in Nature Methods 5(7): 580-581. 2008. PubMed
Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein.
Merten, C.A., Stitz, J., Braun, G., Medvedovska, J., Cichutek, K. & Buchholz, C.J.
Nucleic Acids Res. 2006 Mar 15;34(5):e41. Print 2006. PubMed
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.
Nikles, D., Bach, P., Boller, K., Merten, C.A., Montrasio, F., Heppner, F.L., Aguzzi, A., Cichutek, K., Kalinke, U. & Buchholz, C.J.
J Virol. 2005 Apr;79(7):4033-42. PubMed
Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles.
Merten, C.A., Stitz, J., Braun, G., Poeschla, E.M., Cichutek, K. & Buchholz, C.J.
J Virol. 2005 Jan;79(2):834-40. PubMed
Displaying epidermal growth factor on spleen necrosis virus-derived targeting vectors.
Merten, C.A., Engelstaedter, M., Buchholz, C.J. & Cichutek, K.
Virology. 2003 Jan 5;305(1):106-14. PubMed
10 years of the human genome
EMBL scientists mark a decade since the first draft human genome sequence. Click on the image to play.
Duration: 6 mins.