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Staff at EMBL



Total: 9 publication(s)


Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM. (2014)
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.
Nat Commun 5:5585. doi:10.1038/ncomm6585
Europe PMC | doi

Wilkening S, Lin G, Fritsch ES, Tekkedil MM, Anders S, Kuehn R, Nguyen M, Aiyar RS, Proctor M, Sakhanenko NA, Galas DJ, Gagneur J, Deutschbauer A, Steinmetz LM. (2014)
An evaluation of high-throughput approaches to QTL mapping in Saccharomyces cerevisiae
Genetics 196(3):853-865. doi:10.1534/genetics.113.160291
Europe PMC | doi

Gupta I, Clauder-Münster S, Klaus B, Järvelin AI, Aiyar RS, Benes V, Wilkening S, Huber W, Pelechano V, Steinmetz LM. (2014)
Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions
Mol. Syst. Biol. 10(2):719. doi:10.1002/msb.135068
Europe PMC | doi


Landry JJ, Pyl PT, Rausch T, Zichner T, Tekkedil MM, Stütz AM, Jauch A, Aiyar RS, Pau G, Delhomme N, Gagneur J, Korbel JO, Huber W, Steinmetz LM. (2013)
The genomic and transcriptomic landscape of a HeLa cell line
G3 (Bethesda) 3(8):1213-1224. doi:10.1534/g3.113.005777
Europe PMC | doi

Gagneur J, Stegle O, Zhu C, Jakob P, Tekkedil MM, Aiyar RS, Schuon AK, Pe'er D, Steinmetz LM. (2013)
Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype
PLoS Genet. 9(9):e1003803. doi:10.1371/journal.pgen.1003803
Europe PMC | doi


Bietenhader M, Martos A, Tetaud E, Aiyar RS, Sellem CH, Kucharczyk R, Clauder-Münster S, Giraud MF, Godard F, Salin B, Sagot I, Gagneur J, Déquard-Chablat M, Contamine V, Hermann-Le Denmat S, Sainsard-Chanet A, Steinmetz LM, di Rago JP. (2012)
Experimental relocation of the mitochondrial ATP9 gene to the nucleus reveals forces underlying mitochondrial genome evolution
PLoS Genet. 8(8):e1002876. doi:10.1371/journal.pgen.1002876
Europe PMC | doi


Couplan E, Aiyar RS, Kucharczyk R, Kabala A, Ezkurdia N, Gagneur J, St Onge RP, Salin B, Soubigou F, Le Cann M, Steinmetz LM, di Rago JP, Blondel M. (2011)
A yeast-based assay identifies drugs active against human mitochondrial disorders
Proc. Natl. Acad. Sci. U.S.A. 108(29):11989-11994. doi:10.1073/pnas.1101478108
Europe PMC | doi


Aiyar RS, Gagneur J, Steinmetz LM. (2008)
Identification of mitochondrial disease genes through integrative analysis of multiple datasets
Methods 46(4):248-255. doi:10.1016/j.ymeth.2008.10.002
Europe PMC | doi


Minassian BA, Aiyar R, Alic S, Banwell B, Villanova M, Fardeau M, Mandell JW, Juel VC, Rafii M, Auranen M, Kalimo H. (2002)
Narrowing in on the causative defect of an intriguing X-linked myopathy with excessive autophagy
Neurology 59(4):596-601. doi:10.1212/wnl.59.4.596
Europe PMC | doi