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Staff at EMBL


Vicente Jose Pelechano

Staff Scientist
Steinmetz Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail


Total: 21 publication(s)


Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH. (2014)
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Nat. Struct. Mol. Biol. 21(6):560-568. doi:10.1038/nsmb.2831
Europe PMC | doi

Pelechano V, Wei W, Jakob P, Steinmetz LM. (2014)
Genome-wide identification of transcript start and end sites by transcript isoform sequencing
Nat Protoc 9(7):1740-1759. doi:10.1038/nprot.2014.121
Europe PMC | doi

Gupta I, Clauder-Münster S, Klaus B, Järvelin AI, Aiyar RS, Benes V, Wilkening S, Huber W, Pelechano V, Steinmetz LM. (2014)
Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions
Mol. Syst. Biol. 10(2):719. doi:10.1002/msb.135068
Europe PMC | doi


Pelechano V, Steinmetz LM. (2013)
Gene regulation by antisense transcription
Nat. Rev. Genet. 14(12):880-893. doi:10.1038/nrg3594
Europe PMC | doi

Ntini E, Järvelin AI, Bornholdt J, Chen Y, Boyd M, Jørgensen M, Andersson R, Hoof I, Schein A, Andersen PR, Andersen PK, Preker P, Valen E, Zhao X, Pelechano V, Steinmetz LM, Sandelin A, Jensen TH. (2013)
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality
Nat. Struct. Mol. Biol. 20(8):923-928. doi:10.1038/nsmb.2640
Europe PMC | doi

Wilkening S, Pelechano V, Jarvelin AI, Tekkedil MM, Anders S, Benes V, Steinmetz LM. (2013)
An efficient method for genome-wide polyadenylation site mapping and RNA quantification (vol 41, pg e65, 2013)
Nucleic Acids Res 41(12):6370. doi:10.1093/nar/gkt364

Pelechano V, Wei W, Steinmetz LM. (2013)
Extensive transcriptional heterogeneity revealed by isoform profiling
Nature 497(7447):127-131. doi:10.1038/nature12121
Europe PMC | doi

Wilkening S, Pelechano V, Järvelin AI, Tekkedil MM, Anders S, Benes V, Steinmetz LM. (2013)
An efficient method for genome-wide polyadenylation site mapping and RNA quantification
Nucleic Acids Res. 41(5):e65. doi:10.1093/nar/gks1249
Europe PMC | doi


Schmid M, Poulsen MB, Olszewski P, Pelechano V, Saguez C, Gupta I, Steinmetz LM, Moore C, Jensen TH. (2012)
Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins
Mol. Cell 47(2):267-280. doi:10.1016/j.molcel.2012.05.005
Europe PMC | doi

Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM. (2012)
Genome-wide polyadenylation site mapping
Meth. Enzymol. 513:271-296. doi:10.1016/b978-0-12-391938-0.00012-4
Europe PMC | doi

García-Martínez J, Ayala G, Pelechano V, Chávez S, Herrero E, Pérez-Ortín JE. (2012)
The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast
Transcription 3(1):39-44. doi:10.4161/trns.3.1.19416
Europe PMC | doi


García-López MC, Pelechano V, Mirón-García MC, Garrido-Godino AI, García A, Calvo O, Werner M, Pérez-Ortín JE, Navarro F. (2011)
The conserved foot domain of RNA pol II associates with proteins involved in transcriptional initiation and/or early elongation
Genetics 189(4):1235-1248. doi:10.1534/genetics.111.133215
Europe PMC | doi

Wei W, Pelechano V, Järvelin AI, Steinmetz LM. (2011)
Functional consequences of bidirectional promoters
Trends Genet. 27(7):267-276. doi:10.1016/j.tig.2011.04.002
Europe PMC | doi

Pérez-Ortín JE, Jordán-Pla A, Pelechano V. (2011)
A genomic view of mRNA turnover in yeast
C. R. Biol. 334(8-9):647-654. doi:10.1016/j.crvi.2011.05.013
Europe PMC | doi

García-Martínez J, Pelechano V, Pérez-Ortín JE. (2011)
Genomic-wide methods to evaluate transcription rates in yeast
Methods Mol. Biol. 734:25-44. doi:10.1007/978-1-61779-086-7_2
Europe PMC | doi


Rodríguez-Gil A, García-Martínez J, Pelechano V, Muñoz-Centeno Mde L, Geli V, Pérez-Ortín JE, Chávez S. (2010)
The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
Nucleic Acids Res. 38(14):4651-4664. doi:10.1093/nar/gkq215
Europe PMC | doi

Pelechano V, Pérez-Ortín JE. (2010)
There is a steady-state transcriptome in exponentially growing yeast cells
Yeast 27(7):413-422. doi:10.1002/yea.1768
Europe PMC | doi

Pelechano V, Chávez S, Pérez-Ortín JE. (2010)
A complete set of nascent transcription rates for yeast genes
PLoS ONE 5(11):e15442. doi:10.1371/journal.pone.0015442
Europe PMC | doi


Pelechano V, Jimeno-González S, Rodríguez-Gil A, García-Martínez J, Pérez-Ortín JE, Chávez S. (2009)
Regulon-specific control of transcription elongation across the yeast genome
PLoS Genet. 5(8):e1000614. doi:10.1371/journal.pgen.1000614
Europe PMC | doi


Pelechano V, Pérez-Ortín JE. (2008)
The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast
Yeast 25(2):85-92. doi:10.1002/yea.1548
Europe PMC | doi


Pelechano V, García-Martínez J, Pérez-Ortín JE. (2006)
A genomic study of the inter-ORF distances in Saccharomyces cerevisiae
Yeast 23(9):689-699. doi:10.1002/yea.1390
Europe PMC | doi