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Staff at EMBL


Alessandro Ori

Postdoctoral Fellow
Beck Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail


Total: 14 publication(s)


Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, Bork P. (2014)
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.
Nucleic Acids Res. doi:10.1093/nar/gku1147
Europe PMC | doi

Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH. (2014)
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Nat. Struct. Mol. Biol. 21(6):560-568. doi:10.1038/nsmb.2831
Europe PMC | doi

Ori A, Andrés-Pons A, Beck M. (2014)
The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies.
Methods Cell Biol. 122:117-146. doi:10.1016/b978-0-12-417160-2.00006-0
Europe PMC | doi

Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Lorenzo Bermejo J, Gretz N, Zender L, Schirmacher P, Beck M, Singer S. (2014)
Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.
Hepatology 60(3):884-895. doi:10.1002/hep.27207
Europe PMC | doi


Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M. (2013)
Integrated structural analysis of the human nuclear pore complex scaffold
Cell 155(6):1233-1243. doi:10.1016/j.cell.2013.10.055
Europe PMC | doi

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. (2013)
Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines
Mol. Syst. Biol. 9:648. doi:10.1038/msb.2013.4
Europe PMC | doi


Ori A, Wilkinson MC, Fernig DG. (2011)
A systems biology approach for the investigation of the heparin/heparan sulfate interactome
J. Biol. Chem. 286(22):19892-19904. doi:10.1074/jbc.m111.228114
Europe PMC | doi

Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. (2011)
The quantitative proteome of a human cell line
Mol. Syst. Biol. 7:549. doi:10.1038/msb.2011.82
Europe PMC | doi


Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA. (2010)
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships
Org. Biomol. Chem. 8(23):5390-5397. doi:10.1039/c0ob00246a
Europe PMC | doi

Uniewicz KA, Ori A, Xu R, Ahmed Y, Wilkinson MC, Fernig DG, Yates EA. (2010)
Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity
Anal. Chem. 82(9):3796-3802. doi:10.1021/ac100188x
Europe PMC | doi


Ori A, Free P, Courty J, Wilkinson MC, Fernig DG. (2009)
Identification of heparin-binding sites in proteins by selective labeling
Mol. Cell Proteomics 8(10):2256-2265. doi:10.1074/mcp.m900031-mcp200
Europe PMC | doi

Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA. (2009)
Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution
Biochemistry 48(22):4772-4779. doi:10.1021/bi802318z
Europe PMC | doi


Ori A, Wilkinson MC, Fernig DG. (2008)
The heparanome and regulation of cell function: structures, functions and challenges
Front. Biosci. 13:4309-4338. doi:10.2741/3007
Europe PMC | doi


Bleau AM, Planque N, Lazar N, Zambelli D, Ori A, Quan T, Fisher G, Scotlandi K, Perbal B. (2007)
Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation
J. Cell. Biochem. 101(6):1475-1491. doi:10.1002/jcb.21262
Europe PMC | doi