Staff at EMBL

Alessandro Ori

Postdoctoral Fellow
Beck Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Publications

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Ori, A., Banterle, N., Iskar, M., Andres-Pons, A., Escher, C., Khanh Bui, H., Sparks, L., Solis-Mezarino, V., Rinner, O., Bork, P., Lemke, E.A. & Beck, M. Mol Syst Biol. 2013 Mar 19;9:648. doi: 10.1038/msb.2013.4. PubMed

A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome. Ori, A; Wilkinson, MC; Fernig, DG. Journal of Biological Chemistry Volume: 286 Issue: 22 Pages: 19892-19904 Published: 2011

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. Rudd, T.R., Uniewicz, K.A., Ori, A., Guimond, S.E., Skidmore, M.A., Gaudesi, D., Xu, R., Turnbull, J.E., Guerrini, M., Torri, G., Siligardi, G., Wilkinson, M.C., Fernig, D.G. & Yates, E.A. Org Biomol Chem. 2010 Dec 7;8(23):5390-7. Epub 2010 Sep 3. PubMed

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity. Uniewicz, K.A., Ori, A., Xu, R., Ahmed, Y., Wilkinson, M.C., Fernig, D.G. & Yates, E.A. Anal Chem. 2010 May 1;82(9):3796-802. PubMed

Identification of heparin-binding sites in proteins by selective labeling. Ori, A., Free, P., Courty, J., Wilkinson, M.C. & Fernig, D.G. Mol Cell Proteomics. 2009 Oct;8(10):2256-65. Epub 2009 Jun 30. PubMed

Two Mass Spectrometry Based Approaches for the Investigation of the Heparin Interactome. Ori, A; Wilkinson, MC; Fernig, DG Molecular & Cellular Proteomics Pages: S35-S35 Published: AUG 2009

Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution. Guimond, S.E., Rudd, T.R., Skidmore, M.A., Ori, A., Gaudesi, D., Cosentino, C., Guerrini, M., Edge, R., Collison, D., McInnes, E., Torri, G., Turnbull, J.E., Fernig, D.G. & Yates, E.A. Biochemistry. 2009 Jun 9;48(22):4772-9. PubMed

The heparanome and regulation of cell function: structures, functions and challenges. Ori, A., Wilkinson, M.C. & Fernig, D.G. Front Biosci. 2008 May 1;13:4309-38. PubMed

Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation. Bleau, A.M., Planque, N., Lazar, N., Zambelli, D., Ori, A., Quan, T., Fisher, G., Scotlandi, K. & Perbal, B. J Cell Biochem. 2007 Aug 15;101(6):1475-91. PubMed