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Staff at EMBL

Alessandro Ori

Postdoctoral Fellow
Beck Group

EMBL Heidelberg, Meyerhofstra├če 1, 69117 Heidelberg, Germany

E-mail: send a mail


Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. Piazza, I., Rutkowska, A., Ori, A., Walczak, M., Metz, J., Pelechano, V., Beck, M. & Haering, C.H. Nat Struct Mol Biol. 2014 Jun;21(6):560-8. doi: 10.1038/nsmb.2831. Epub 2014 May18. Europe PMC

Prosurvival function of the cellular apoptosis susceptibility/importin-alpha1 transport cycle is repressed by p53 in liver cancer. Winkler, J., Ori, A., Holzer, K., Sticht, C., Dauch, D., Eiteneuer, E.M., Pinna, F., Geffers, R., Ehemann, V., Andres-Pons, A., Breuhahn, K., Longerich, T., Lorenzo Bermejo, J., Gretz, N., Zender, L., Schirmacher, P., Beck, M. & Singer, S. Hepatology. 2014 May 6. doi: 10.1002/hep.27207. Europe PMC

The Use of Targeted Proteomics to Determine the Stoichiometry of Large Macromolecular Assemblies. Ori, A., Andres-Pons, A. & Beck, M. Methods Cell Biol. 2014;122C:117-146. doi: 10.1016/B978-0-12-417160-2.00006-0. Europe PMC

Integrated structural analysis of the human nuclear pore complex scaffold. Bui, K.H., von Appen, A., DiGuilio, A.L., Ori, A., Sparks, L., Mackmull, M.T., Bock, T., Hagen, W., Andres-Pons, A., Glavy, J.S. & Beck, M. Cell. 2013 Dec 5;155(6):1233-43. doi: 10.1016/j.cell.2013.10.055. Europe PMC

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Ori, A., Banterle, N., Iskar, M., Andres-Pons, A., Escher, C., Khanh Bui, H., Sparks, L., Solis-Mezarino, V., Rinner, O., Bork, P., Lemke, E.A. & Beck, M. Mol Syst Biol. 2013 Mar 19;9:648. doi: 10.1038/msb.2013.4. Europe PMC

A systems biology approach for the investigation of the heparin/heparan sulfate interactome. Ori, A., Wilkinson, M.C. & Fernig, D.G. J Biol Chem. 2011 Jun 3;286(22):19892-904. doi: 10.1074/jbc.M111.228114. Epub2011 Mar 30. Europe PMC

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. Rudd, T.R., Uniewicz, K.A., Ori, A., Guimond, S.E., Skidmore, M.A., Gaudesi, D., Xu, R., Turnbull, J.E., Guerrini, M., Torri, G., Siligardi, G., Wilkinson, M.C., Fernig, D.G. & Yates, E.A. Org Biomol Chem. 2010 Dec 7;8(23):5390-7. Epub 2010 Sep 3. Europe PMC

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity. Uniewicz, K.A., Ori, A., Xu, R., Ahmed, Y., Wilkinson, M.C., Fernig, D.G. & Yates, E.A. Anal Chem. 2010 May 1;82(9):3796-802. Europe PMC

Identification of heparin-binding sites in proteins by selective labeling. Ori, A., Free, P., Courty, J., Wilkinson, M.C. & Fernig, D.G. Mol Cell Proteomics. 2009 Oct;8(10):2256-65. Epub 2009 Jun 30. Europe PMC

Two Mass Spectrometry Based Approaches for the Investigation of the Heparin Interactome. Ori, A; Wilkinson, MC; Fernig, DG Molecular & Cellular Proteomics Pages: S35-S35 Published: AUG 2009

Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution. Guimond, S.E., Rudd, T.R., Skidmore, M.A., Ori, A., Gaudesi, D., Cosentino, C., Guerrini, M., Edge, R., Collison, D., McInnes, E., Torri, G., Turnbull, J.E., Fernig, D.G. & Yates, E.A. Biochemistry. 2009 Jun 9;48(22):4772-9. Europe PMC

The heparanome and regulation of cell function: structures, functions and challenges. Ori, A., Wilkinson, M.C. & Fernig, D.G. Front Biosci. 2008 May 1;13:4309-38. Europe PMC

Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation. Bleau, A.M., Planque, N., Lazar, N., Zambelli, D., Ori, A., Quan, T., Fisher, G., Scotlandi, K. & Perbal, B. J Cell Biochem. 2007 Aug 15;101(6):1475-91. Europe PMC