Total: 23 publication(s)


Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M. (2015)

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats.

Cell Sys 1(3):224-237. doi:10.1016/j.cels.2015.08.012

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M. (2015)

In situ structural analysis of the human nuclear pore complex.

Nature 526(7571):140-143. doi:10.1038/nature15381
Europe PMC | doi

Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressler D, Bange G, Hurt E, Beck M, Sinning I. (2015)

Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site.

Nat Commun 6:6510. doi:10.1038/ncomms7510
Europe PMC | doi

Mackmull MT, Iskar M, Parca L, Singer S, Bork P, Ori A, Beck M. (2015)

Histone deacetylase inhibitors cause the selective depletion of bromodomain containing proteins.

Mol. Cell Proteomics doi:10.1074/mcp.m114.042499
Europe PMC | doi

Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M. (2015)

Xlink Analyzer: Software for analysis and visualization of cross-linking data in the context of three-dimensional structures.

J. Struct. Biol. 189(3):177-183. doi:10.1016/j.jsb.2015.01.014
Europe PMC | doi

Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E. (2015)

Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.

J. Cell Biol. 208(3):283-297. doi:10.1083/jcb.201411003
Europe PMC | doi


Dos Santos C, Blanc C, Elahouel R, Prescott M, Carpentier G, Ori A, Courty J, Hamma-Kourbali Y, Fernig DG, Delbé J. (2014)

Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide.

Biochimie 107(Pt B):350-357. doi:10.1016/j.biochi.2014.10.002
Europe PMC | doi

Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, Bork P. (2014)

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.

Nucleic Acids Res. 42(22):13525-13533. doi:10.1093/nar/gku1147
Europe PMC | doi

Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Lorenzo Bermejo J, Gretz N, Zender L, Schirmacher P, Beck M, Singer S. (2014)

Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.

Hepatology 60(3):884-895. doi:10.1002/hep.27207
Europe PMC | doi

Uniewicz KA, Ori A, Ahmed YA, Yates EA, Fernig DG. (2014)

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars.

PeerJ 2:e461. doi:10.7717/peerj.461
Europe PMC | doi

Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH. (2014)

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits

Nat. Struct. Mol. Biol. 21(6):560-568. doi:10.1038/nsmb.2831
Europe PMC | doi

Ori A, Andrés-Pons A, Beck M. (2014)

The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies.

Methods Cell Biol. 122:117-146. doi:10.1016/b978-0-12-417160-2.00006-0
Europe PMC | doi


Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M. (2013)

Integrated structural analysis of the human nuclear pore complex scaffold.

Cell 155(6):1233-1243. doi:10.1016/j.cell.2013.10.055
Europe PMC | doi

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. (2013)

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

Mol. Syst. Biol. 9:648. doi:10.1038/msb.2013.4
Europe PMC | doi


Uniewicz KA, Ori A, Rudd TR, Guerrini M, Wilkinson MC, Fernig DG, Yates EA. (2012)

Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry.

Methods Mol. Biol. 836:171-182. doi:10.1007/978-1-61779-498-8_12
Europe PMC | doi


Ori A, Wilkinson MC, Fernig DG. (2011)

A systems biology approach for the investigation of the heparin/heparan sulfate interactome

J. Biol. Chem. 286(22):19892-19904. doi:10.1074/jbc.m111.228114
Europe PMC | doi

Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. (2011)

The quantitative proteome of a human cell line

Mol. Syst. Biol. 7:549. doi:10.1038/msb.2011.82
Europe PMC | doi


Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA. (2010)

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships

Org. Biomol. Chem. 8(23):5390-5397. doi:10.1039/c0ob00246a
Europe PMC | doi

Uniewicz KA, Ori A, Xu R, Ahmed Y, Wilkinson MC, Fernig DG, Yates EA. (2010)

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity

Anal. Chem. 82(9):3796-3802. doi:10.1021/ac100188x
Europe PMC | doi


Ori A, Free P, Courty J, Wilkinson MC, Fernig DG. (2009)

Identification of heparin-binding sites in proteins by selective labeling

Mol. Cell Proteomics 8(10):2256-2265. doi:10.1074/mcp.m900031-mcp200
Europe PMC | doi

Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA. (2009)

Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution

Biochemistry 48(22):4772-4779. doi:10.1021/bi802318z
Europe PMC | doi


Ori A, Wilkinson MC, Fernig DG. (2008)

The heparanome and regulation of cell function: structures, functions and challenges

Front. Biosci. 13:4309-4338. doi:10.2741/3007
Europe PMC | doi


Bleau AM, Planque N, Lazar N, Zambelli D, Ori A, Quan T, Fisher G, Scotlandi K, Perbal B. (2007)

Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation

J. Cell. Biochem. 101(6):1475-1491. doi:10.1002/jcb.21262
Europe PMC | doi