Beck GroupPublications
The quantitative proteome of a human cell line.
Beck, M., Schmidt, A., Malmstroem, J., Claassen, M., Ori, A., Szymborska, A., Herzog, F., Rinner, O., Ellenberg, J. & Aebersold, R.
Mol Syst Biol. 2011 Nov 8;7:549. doi: 10.1038/msb.2011.82. PubMed
Absolute quantification of microbial proteomes at different states by directed mass spectrometry.
Schmidt, A., Beck, M., Malmstrom, J., Lam, H., Claassen, M., Campbell, D. & Aebersold, R.
Mol Syst Biol. 2011 Jul 19;7:510. doi: 10.1038/msb.2011.37. PubMed
Template-free detection of macromolecular complexes in cryo electron tomograms.
Xu, M., Beck, M. & Alber, F.
Bioinformatics. 2011 Jul 1;27(13):i69-i76. PubMed
mProphet: automated data processing and statistical validation for large-scale SRM experiments.
Reiter, L., Rinner, O., Picotti, P., Huttenhain, R., Beck, M., Brusniak, M.Y., Hengartner, M.O. & Aebersold, R.
Nat Methods. 2011 Mar 20. PubMed
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.
Bohn, S., Beck, F., Sakata, E., Walzthoeni, T., Beck, M., Aebersold, R., Forster, F., Baumeister, W. & Nickell, S.
Proc Natl Acad Sci U S A. 2010 Nov 22. PubMed
Exploring the Spatial and Temporal Organization of a Cell's Proteome.
Beck, M., Topf, M., Frazier, Z., Tjong, H., Xu, M., Zhang, S. & Alber, F.
J Struct Biol. 2010 Nov 19. PubMed
Comprehensive proteomics.
Beck, M., Claassen, M. & Aebersold, R.
Curr Opin Biotechnol. 2010 Sep 29. PubMed
Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics.
Leitner, A., Walzthoeni, T., Kahraman, A., Herzog, F., Rinner, O., Beck, M. & Aebersold, R.
Mol Cell Proteomics. 2010 Aug;9(8):1634-49. Epub 2010 Mar 31. PubMed
Visual proteomics.
Forster, F., Han, B.G. & Beck, M.
Methods Enzymol. 2010;483:215-43. PubMed
Visual proteomics of the human pathogen Leptospira interrogans.
Beck, M., Malmstrom, J.A., Lange, V., Schmidt, A., Deutsch, E.W. & Aebersold, R.
Nat Methods. 2009 Nov;6(11):817-23. Epub 2009 Oct 18. PubMed
Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans.
Malmstrom, J., Beck, M., Schmidt, A., Lange, V., Deutsch, E.W. & Aebersold, R.
Nature. 2009 Aug 6;460(7256):762-5. Epub 2009 Jul 15. PubMed
Architecture and molecular mechanism of PAN, the archaeal proteasome regulatory ATPase.
Medalia, N., Beer, A., Zwickl, P., Mihalache, O., Beck, M., Medalia, O. & Navon, A.
J Biol Chem. 2009 Aug 21;284(34):22952-60. Epub 2009 Apr 10. PubMed
Structural and functional insights into nucleocytoplasmic transport.
Beck, M. & Medalia, O.
Histol Histopathol. 2008 Aug;23(8):1025-33. PubMed
Identification of cross-linked peptides from large sequence databases.
Rinner, O., Seebacher, J., Walzthoeni, T., Mueller, L.N., Beck, M., Schmidt, A., Mueller, M. & Aebersold, R.
Nat Methods. 2008 Apr;5(4):315-8. Epub 2008 Mar 9. PubMed
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography.
Beck, M., Lucic, V., Forster, F., Baumeister, W. & Medalia, O.
Nature. 2007 Oct 4;449(7162):611-5. Epub 2007 Sep 12. PubMed
Organization of actin networks in intact filopodia.
Medalia, O., Beck, M., Ecke, M., Weber, I., Neujahr, R., Baumeister, W. & Gerisch, G.
Curr Biol. 2007 Jan 9;17(1):79-84. PubMed
Luminal particles within cellular microtubules.
Garvalov, B.K., Zuber, B., Bouchet-Marquis, C., Kudryashev, M., Gruska, M., Beck, M., Leis, A., Frischknecht, F., Bradke, F., Baumeister, W., Dubochet, J. & Cyrklaff, M.
J Cell Biol. 2006 Sep 11;174(6):759-65. Epub 2006 Sep 5. PubMed
Cryo-electron tomography of biological specimens.
Leis, A. P., Beck, M., Gruska, M., Best, C., Hegerl, R., Baumeister, W., and Leis, J. W.
IEEE Signal Processing Magazine
Nuclear pore complex structure and dynamics revealed by cryoelectron tomography.
Beck, M., Forster, F., Ecke, M., Plitzko, J.M., Melchior, F., Gerisch, G., Baumeister, W. & Medalia, O.
Science. 2004 Nov 19;306(5700):1387-90. Epub 2004 Oct 28. PubMed
Podcast on Cryo-electron microscopy
Sarah Stanley talks to EMBL scientists about cryo-EM. Click on the image to play.
Duration: 7 mins.
Download script