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Publications

Total: 9 publication(s)

2014

Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D. (2014)

Luminal signalling links cell communication to tissue architecture during organogenesis.

Nature 515(7525):120-124. doi:10.1038/nature13852
Europe PMC | doi

van Noort VV, Schölch S, Iskar M, Zeller G, Ostertag K, Schweitzer C, Werner K, Weitz J, Koch M, Bork P. (2014)

Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene expression profiling

Cancer Res. doi:10.1158/0008-5472.CAN-13-3540
Europe PMC | doi


2013

Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P. (2013)

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

Mol. Syst. Biol. 9:662. doi:10.1038/msb.2013.20
Europe PMC | doi

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. (2013)

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

Mol. Syst. Biol. 9:648. doi:10.1038/msb.2013.4
Europe PMC | doi

Pacini C, Iorio F, Gonçalves E, Iskar M, Klabunde T, Bork P, Saez-Rodriguez J. (2013)

DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data

Bioinformatics 29(1):132-134. doi:10.1093/bioinformatics/bts656
Europe PMC | doi


2012

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P. (2012)

Drug discovery in the age of systems biology: the rise of computational approaches for data integration

Curr. Opin. Biotechnol. 23(4):609-616. doi:10.1016/j.copbio.2011.11.010
Europe PMC | doi


2011

Zhao XM, Iskar M, Zeller G, Kuhn M, van Noort V, Bork P. (2011)

Prediction of drug combinations by integrating molecular and pharmacological data

PLoS Comput. Biol. 7(12):e1002323. doi:10.1371/journal.pcbi.1002323
Europe PMC | doi

Brouwers L, Iskar M, Zeller G, van Noort V, Bork P. (2011)

Network neighbors of drug targets contribute to drug side-effect similarity

PLoS ONE 6(7):e22187. doi:10.1371/journal.pone.0022187
Europe PMC | doi


2010

Iskar M, Campillos M, Kuhn M, Jensen LJ, van Noort V, Bork P. (2010)

Drug-induced regulation of target expression

PLoS Comput. Biol. 6(9):289-301. doi:10.1371/journal.pcbi.1000925
Europe PMC | doi