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Staff at EMBL

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Publications

Total: 8 publication(s)

2014

van Noort VV, Schölch S, Iskar M, Zeller G, Ostertag K, Schweitzer C, Werner K, Weitz J, Koch M, Bork P. (2014)
Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene expression profiling
Cancer Res. doi:10.1158/0008-5472.CAN-13-3540
Europe PMC | doi


2013

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. (2013)
Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines
Mol. Syst. Biol. 9:648. doi:10.1038/msb.2013.4
Europe PMC | doi

Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P. (2013)
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding
Mol. Syst. Biol. 9:662. doi:10.1038/msb.2013.20
Europe PMC | doi

Pacini C, Iorio F, Gonçalves E, Iskar M, Klabunde T, Bork P, Saez-Rodriguez J. (2013)
DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
Bioinformatics 29(1):132-134. doi:10.1093/bioinformatics/bts656
Europe PMC | doi


2012

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P. (2012)
Drug discovery in the age of systems biology: the rise of computational approaches for data integration
Curr. Opin. Biotechnol. 23(4):609-616. doi:10.1016/j.copbio.2011.11.010
Europe PMC | doi


2011

Zhao XM, Iskar M, Zeller G, Kuhn M, van Noort V, Bork P. (2011)
Prediction of drug combinations by integrating molecular and pharmacological data
PLoS Comput. Biol. 7(12):e1002323. doi:10.1371/journal.pcbi.1002323
Europe PMC | doi

Brouwers L, Iskar M, Zeller G, van Noort V, Bork P. (2011)
Network neighbors of drug targets contribute to drug side-effect similarity
PLoS ONE 6(7):e22187. doi:10.1371/journal.pone.0022187
Europe PMC | doi


2010

Iskar M, Campillos M, Kuhn M, Jensen LJ, van Noort V, Bork P. (2010)
Drug-induced regulation of target expression
PLoS Comput. Biol. 6(9):289-301. doi:10.1371/journal.pcbi.1000925
Europe PMC | doi