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Total: 5 publication(s)


Driessen M, Vitins AP, Pennings JL, Kienhuis AS, Water BV, van der Ven LT. (2015)

A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.

Toxicol. Lett. 232(2):403-412. doi:10.1016/j.toxlet.2014.11.020
Europe PMC | doi


Driessen M, Kienhuis AS, Vitins AP, Pennings JL, Pronk TE, Brandhof EJ, Roodbergen M, Water BV, Ven LT. (2014)

Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans

Toxicol. Lett. 230(1):48-56. doi:10.1016/j.toxlet.2014.06.844
Europe PMC | doi


Driessen M, Kienhuis AS, Pennings JL, Pronk TE, van de Brandhof EJ, Roodbergen M, Spaink HP, van de Water B, van der Ven LT. (2013)

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling.

Arch. Toxicol. 87(5):807-823. doi:10.1007/s00204-013-1039-z
Europe PMC | doi


Kienhuis AS, Bessems JG, Pennings JL, Driessen M, Luijten M, van Delft JH, Peijnenburg AA, van der Ven LT. (2011)

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Toxicol. Appl. Pharmacol. 250(2):96-107. doi:10.1016/j.taap.2010.10.013
Europe PMC | doi


Pullen J, Driessen M, Stolk LM, Degraeuwe PL, van Tiel FH, Neef C, Zimmermann LJ. (2007)

Amoxicillin pharmacokinetics in (preterm) infants aged 10 to 52 days: effect of postnatal age.

Ther Drug Monit 29(3):376-380. doi:10.1097/ftd.0b013e318067de5c
Europe PMC | doi