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Staff at EMBL

Wim Hagen

Senior Engineer in Electron Microscopy
Briggs Group

EMBL Heidelberg, Meyerhofstra├če 1, 69117 Heidelberg, Germany

E-mail: send a mail


Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly. Bharat, T.A., Castillo Menendez, L.R., Hagen, W.J., Lux, V., Igonet, S., Schorb, M., Schur, F.K., Krausslich, H.G. & Briggs, J.A. Proc Natl Acad Sci U S A. 2014 May 19. pii: 201401455. Europe PMC

SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion. Bharat, T.A., Malsam, J., Hagen, W.J., Scheutzow, A., Sollner, T.H. & Briggs, J.A. EMBO Rep. 2014 Mar;15(3):308-14. doi: 10.1002/embr.201337807. Epub 2014 Feb 3. Europe PMC

Integrated structural analysis of the human nuclear pore complex scaffold. Bui, K.H., von Appen, A., DiGuilio, A.L., Ori, A., Sparks, L., Mackmull, M.T., Bock, T., Hagen, W., Andres-Pons, A., Glavy, J.S. & Beck, M. Cell. 2013 Dec 5;155(6):1233-43. doi: 10.1016/j.cell.2013.10.055. Europe PMC

Determination of protein structure at 8.5A resolution using cryo-electron tomography and sub-tomogram averaging. Schur, F.K., Hagen, W.J., de Marco, A. & Briggs, J.A. J Struct Biol. 2013 Dec;184(3):394-400. doi: 10.1016/j.jsb.2013.10.015. Epub 2013Oct 30. Europe PMC