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Briggs GroupPublications

Total: 57 publication(s)

2014

Schur FK, Hagen WJ, Rumlová M, Ruml T, Müller B, Kräusslich HG, Briggs JA. (2014)
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 A resolution.
Nature
Europe PMC

Mattei S, Anders M, Konvalinka J, Kräusslich HG, Briggs JA, Müller B. (2014)
Induced maturation of human immunodeficiency virus
J. Virol. doi:10.1128/JVI.02271-14
Europe PMC | doi

Daum S, Krüger D, Meister A, Auerswald J, Prinz S, Briggs JA, Bacia K. (2014)
Insights from reconstitution reactions of COPII vesicle formation using pure components and low mechanical perturbation.
Biol. Chem. 395(7-8):801-812. doi:10.1515/hsz-2014-0117
Europe PMC | doi

Stauffer S, Rahman SA, de Marco A, Carlson LA, Glass B, Oberwinkler H, Herold N, Briggs JA, Müller B, Grünewald K, Kräusslich HG. (2014)
The Nucleocapsid Domain of Gag Is Dispensable for Actin Incorporation into HIV-1 and for Association of Viral Budding Sites with Cortical F-Actin
J. Virol. 88(14):7893-7903. doi:10.1128/jvi.00428-14
Europe PMC | doi

Bharat TA, Castillo Menendez LR, Hagen WJ, Lux V, Igonet S, Schorb M, Schur FK, Kräusslich HG, Briggs JA. (2014)
Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly
Proc. Natl. Acad. Sci. U.S.A. 111(22):8233-8238. doi:10.1073/pnas.1401455111
Europe PMC | doi

Bharat TA, Malsam J, Hagen WJ, Scheutzow A, Söllner TH, Briggs JA. (2014)
SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion
EMBO Rep. 15(3):308-314. doi:10.1002/embr.201337807
Europe PMC | doi

Nikić I, Plass T, Schraidt O, Szymański J, Briggs JA, Schultz C, Lemke EA. (2014)
Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy
Angew. Chem. Int. Ed. Engl. doi:10.1002/anie.201309847
Europe PMC | doi


2013

Schur FK, Hagen WJ, de Marco A, Briggs JA. (2013)
Determination of protein structure at 8.5A resolution using cryo-electron tomography and sub-tomogram averaging
J. Struct. Biol. 184(3):394-400. doi:10.1016/j.jsb.2013.10.015
Europe PMC | doi

Schorb M, Briggs JA. (2013)
Correlated cryo-fluorescence and cryo-electron microscopy with high spatial precision and improved sensitivity
Ultramicroscopy doi:10.1016/j.ultramic.2013.10.015
Europe PMC | doi

Szymborska A, de Marco A, Daigle N, Cordes VC, Briggs JA, Ellenberg J. (2013)
Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging
Science 341(6146):655-658. doi:10.1126/science.1240672
Europe PMC | doi

Bharat TA, Zbaida D, Eisenstein M, Frankenstein Z, Mehlman T, Weiner L, Sorzano CO, Barak Y, Albeck S, Briggs JA, Wolf SG, Elbaum M. (2013)
Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA
Structure 21(7):1158-1167. doi:10.1016/j.str.2013.04.027
Europe PMC | doi

Faini M, Beck R, Wieland FT, Briggs JA. (2013)
Vesicle coats: structure, function, and general principles of assembly
Trends Cell Biol. 23(6):279-288. doi:10.1016/j.tcb.2013.01.005
Europe PMC | doi

Briggs JA. (2013)
Structural biology in situ--the potential of subtomogram averaging
Curr. Opin. Struct. Biol. 23(2):261-267. doi:10.1016/j.sbi.2013.02.003
Europe PMC | doi

Zanetti G, Prinz S, Daum S, Meister A, Schekman R, Bacia K, Briggs JA. (2013)
The structure of the COPII transport-vesicle coat assembled on membranes
Elife 2:e00951. doi:10.7554/elife.00951
Europe PMC | doi

Fabrowski P, Necakov AS, Mumbauer S, Loeser E, Reversi A, Streichan S, Briggs JA, De Renzis S. (2013)
Tubular endocytosis drives remodelling of the apical surface during epithelial morphogenesis in Drosophila
Nat Commun 4:2244. doi:10.1038/ncomms3244
Europe PMC | doi


2012

de Marco A, Heuser AM, Glass B, Kräusslich HG, Müller B, Briggs JA. (2012)
Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity
J. Virol. 86(24):13708-13716. doi:10.1128/jvi.01704-12
Europe PMC | doi

Malsam J, Parisotto D, Bharat TA, Scheutzow A, Krause JM, Briggs JA, Söllner TH. (2012)
Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release
EMBO J. 31(15):3270-3281. doi:10.1038/emboj.2012.164
Europe PMC | doi

Steringer JP, Bleicken S, Andreas H, Zacherl S, Laussmann M, Temmerman K, Contreras FX, Bharat TA, Lechner J, Müller HM, Briggs JA, García-Sáez AJ, Nickel W. (2012)
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion
J. Biol. Chem. 287(33):27659-27669. doi:10.1074/jbc.m112.381939
Europe PMC | doi

Kukulski W, Schorb M, Kaksonen M, Briggs JA. (2012)
Plasma membrane reshaping during endocytosis is revealed by time-resolved electron tomography
Cell 150(3):508-520. doi:10.1016/j.cell.2012.05.046
Europe PMC | doi

Bharat TA, Davey NE, Ulbrich P, Riches JD, de Marco A, Rumlova M, Sachse C, Ruml T, Briggs JA. (2012)
Structure of the immature retroviral capsid at 8 A resolution by cryo-electron microscopy
Nature 487(7407):385-389. doi:10.1038/nature11169
Europe PMC | doi

Faini M, Prinz S, Beck R, Schorb M, Riches JD, Bacia K, Brügger B, Wieland FT, Briggs JA. (2012)
The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions
Science 336(6087):1451-1454. doi:10.1126/science.1221443
Europe PMC | doi

Briggs JAG, Lakadamyali M. (2012)
Imaging cellular structure across scales with correlated light, superresolution, and electron microscopy.
Mol. Biol. Cell 23(6):979-980.
Europe PMC

Bharat TA, Noda T, Riches JD, Kraehling V, Kolesnikova L, Becker S, Kawaoka Y, Briggs JA. (2012)
Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography
Proc. Natl. Acad. Sci. U.S.A. 109(11):4275-4280. doi:10.1073/pnas.1120453109
Europe PMC | doi

Hadravová R, de Marco A, Ulbrich P, Stokrová J, Dolezal M, Pichová I, Ruml T, Briggs JA, Rumlová M. (2012)
In vitro assembly of virus-like particles of a gammaretrovirus, the murine leukemia virus XMRV
J. Virol. 86(3):1297-1306. doi:10.1128/jvi.05564-11
Europe PMC | doi

Kalinina OV, Oberwinkler H, Glass B, Kräusslich HG, Russell RB, Briggs JA. (2012)
Computational identification of novel amino-acid interactions in HIV Gag via correlated evolution
PLoS ONE 7(8):e42468. doi:10.1371/journal.pone.0042468
Europe PMC | doi

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. (2012)
Precise, correlated fluorescence microscopy and electron tomography of lowicryl sections using fluorescent fiducial markers
Methods Cell Biol. 111:235-257. doi:10.1016/b978-0-12-416026-2.00013-3
Europe PMC | doi


2011

Bharat TA, Riches JD, Kolesnikova L, Welsch S, Krähling V, Davey N, Parsy ML, Becker S, Briggs JA. (2011)
Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells
PLoS Biol. 9(11):e1001196. doi:10.1371/journal.pbio.1001196
Europe PMC | doi

Beck R, Prinz S, Diestelkötter-Bachert P, Röhling S, Adolf F, Hoehner K, Welsch S, Ronchi P, Brügger B, Briggs JA, Wieland F. (2011)
Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission
J. Cell Biol. 194(5):765-777. doi:10.1083/jcb.201011027
Europe PMC | doi

Briggs JA, Kräusslich HG. (2011)
The molecular architecture of HIV
J. Mol. Biol. 410(4):491-500. doi:10.1016/j.jmb.2011.04.021
Europe PMC | doi

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. (2011)
Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision
J. Cell Biol. 192(1):111-119. doi:10.1083/jcb.201009037
Europe PMC | doi

Bacia K, Futai E, Prinz S, Meister A, Daum S, Glatte D, Briggs JA, Schekman R. (2011)
Multibudded tubules formed by COPII on artificial liposomes
Sci Rep 1:17. doi:10.1038/srep00017
Europe PMC | doi


2010

de Marco A, Davey NE, Ulbrich P, Phillips JM, Lux V, Riches JD, Fuzik T, Ruml T, Kräusslich HG, Vogt VM, Briggs JA. (2010)
Conserved and variable features of Gag structure and arrangement in immature retrovirus particles
J. Virol. 84(22):11729-11736. doi:10.1128/jvi.01423-10
Europe PMC | doi

Welsch S, Kolesnikova L, Krähling V, Riches JD, Becker S, Briggs JA. (2010)
Electron tomography reveals the steps in filovirus budding
PLoS Pathog. 6(4):e1000875. doi:10.1371/journal.ppat.1000875
Europe PMC | doi

Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ. (2010)
Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition
J. Virol. 84(7):3516-3527. doi:10.1128/jvi.02651-09
Europe PMC | doi

Carlson LA, de Marco A, Oberwinkler H, Habermann A, Briggs JA, Kräusslich HG, Grünewald K. (2010)
Cryo electron tomography of native HIV-1 budding sites
PLoS Pathog. 6(11):e1001173. doi:10.1371/journal.ppat.1001173
Europe PMC | doi

de Marco A, Müller B, Glass B, Riches JD, Kräusslich HG, Briggs JA. (2010)
Structural analysis of HIV-1 maturation using cryo-electron tomography
PLoS Pathog. 6(11):e1001215. doi:10.1371/journal.ppat.1001215
Europe PMC | doi


2009

Fabrikant G, Lata S, Riches JD, Briggs JA, Weissenhorn W, Kozlov MM. (2009)
Computational model of membrane fission catalyzed by ESCRT-III
PLoS Comput. Biol. 5(11):e1000575. doi:10.1371/journal.pcbi.1000575
Europe PMC | doi

Zanetti G, Riches JD, Fuller SD, Briggs JA. (2009)
Contrast transfer function correction applied to cryo-electron tomography and sub-tomogram averaging
J. Struct. Biol. 168(2):305-312. doi:10.1016/j.jsb.2009.08.002
Europe PMC | doi

Briggs JA, Riches JD, Glass B, Bartonova V, Zanetti G, Kräusslich HG. (2009)
Structure and assembly of immature HIV
Proc. Natl. Acad. Sci. U.S.A. 106(27):11090-11095. doi:10.1073/pnas.0903535106
Europe PMC | doi


2008

Carlson LA, Briggs JA, Glass B, Riches JD, Simon MN, Johnson MC, Müller B, Grünewald K, Kräusslich HG. (2008)
Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis
Cell Host Microbe 4(6):592-599. doi:10.1016/j.chom.2008.10.013
Europe PMC | doi

Endress T, Lampe M, Briggs JA, Kräusslich HG, Bräuchle C, Müller B, Lamb DC. (2008)
HIV-1-cellular interactions analyzed by single virus tracing
Eur. Biophys. J. 37(8):1291-1301. doi:10.1007/s00249-008-0322-z
Europe PMC | doi


2007

Huiskonen JT, Jäälinoja HT, Briggs JA, Fuller SD, Butcher SJ. (2007)
Structure of a hexameric RNA packaging motor in a viral polymerase complex
J. Struct. Biol. 158(2):156-164. doi:10.1016/j.jsb.2006.08.021
Europe PMC | doi

Lampe M, Briggs JA, Endress T, Glass B, Riegelsberger S, Kräusslich HG, Lamb DC, Bräuchle C, Müller B. (2007)
Double-labelled HIV-1 particles for study of virus-cell interaction
Virology 360(1):92-104. doi:10.1016/j.virol.2006.10.005
Europe PMC | doi


2006

Zanetti G, Briggs JA, Grünewald K, Sattentau QJ, Fuller SD. (2006)
Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ
PLoS Pathog. 2(8):e83. doi:10.1371/journal.ppat.0020083
Europe PMC | doi

Briggs JA, Johnson MC, Simon MN, Fuller SD, Vogt VM. (2006)
Cryo-electron microscopy reveals conserved and divergent features of gag packing in immature particles of Rous sarcoma virus and human immunodeficiency virus
J. Mol. Biol. 355(1):157-168. doi:10.1016/j.jmb.2005.10.025
Europe PMC | doi

Briggs JA, Grünewald K, Glass B, Förster F, Kräusslich HG, Fuller SD. (2006)
The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions
Structure 14(1):15-20. doi:10.1016/j.str.2005.09.010
Europe PMC | doi


2005

Briggs JA, Huiskonen JT, Fernando KV, Gilbert RJ, Scotti P, Butcher SJ, Fuller SD. (2005)
Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles
J. Struct. Biol. 150(3):332-339. doi:10.1016/j.jsb.2005.03.009
Europe PMC | doi


2004

Briggs JA, Simon MN, Gross I, Kräusslich HG, Fuller SD, Vogt VM, Johnson MC. (2004)
The stoichiometry of Gag protein in HIV-1
Nat. Struct. Mol. Biol. 11(7):672-675. doi:10.1038/nsmb785
Europe PMC | doi

Briggs JA, Watson BE, Gowen BE, Fuller SD. (2004)
Cryoelectron microscopy of mouse mammary tumor virus
J. Virol. 78(5):2606-2608. doi:10.1128/jvi.78.5.2606-2608.2004
Europe PMC | doi


2003

Schwarz-Linek U, Werner JM, Pickford AR, Gurusiddappa S, Kim JH, Pilka ES, Briggs JA, Gough TS, Höök M, Campbell ID, Potts JR. (2003)
Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper
Nature 423(6936):177-181. doi:10.1038/nature01589
Europe PMC | doi

Briggs JA, Wilk T, Fuller SD. (2003)
Do lipid rafts mediate virus assembly and pseudotyping?
J. Gen. Virol. 84(Pt 4):757-768. doi:10.1099/vir.0.18779-0
Europe PMC | doi

Briggs JA, Wilk T, Welker R, Kräusslich HG, Fuller SD. (2003)
Structural organization of authentic, mature HIV-1 virions and cores
EMBO J. 22(7):1707-1715. doi:10.1093/emboj/cdg143
Europe PMC | doi


2002

Torres J, Briggs JA, Arkin IT. (2002)
Contribution of energy values to the analysis of global searching molecular dynamics simulations of transmembrane helical bundles
Biophys. J. 82(6):3063-3071. doi:10.1016/s0006-3495(02)75647-6
Europe PMC | doi

Rous BA, Reaves BJ, Ihrke G, Briggs JA, Gray SR, Stephens DJ, Banting G, Luzio JP. (2002)
Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes
Mol. Biol. Cell 13(3):1071-1082. doi:10.1091/mbc.01-08-0409
Europe PMC | doi

Torres J, Briggs JA, Arkin IT. (2002)
Convergence of experimental, computational and evolutionary approaches predicts the presence of a tetrameric form for CD3-zeta
J. Mol. Biol. 316(2):375-384. doi:10.1006/jmbi.2001.5268
Europe PMC | doi

Torres J, Briggs JA, Arkin IT. (2002)
Multiple site-specific infrared dichroism of CD3-zeta, a transmembrane helix bundle
J. Mol. Biol. 316(2):365-374. doi:10.1006/jmbi.2001.5267
Europe PMC | doi


2001

Briggs JA, Torres J, Arkin IT. (2001)
A new method to model membrane protein structure based on silent amino acid substitutions
Proteins 44(3):370-375. doi:10.1002/prot.1102
Europe PMC | doi