EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

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Publications

Total: 43 publication(s)

2015

Simon B, Masiewicz P, Ephrussi A, Carlomagno T. (2015)

The structure of the SOLE element of oskar mRNA.

RNA doi:10.1261/rna.049601.115
Europe PMC | doi

Hennig J, Warner LR, Simon B, Geerlof A, Mackereth CD, Sattler M. (2015)

Structural Analysis of Protein-RNA Complexes in Solution Using NMR Paramagnetic Relaxation Enhancements.

Meth. Enzymol. 558:333-362. doi:10.1016/bs.mie.2015.02.006
Europe PMC | doi

Marchanka A, Simon B, Althoff-Ospelt G, Carlomagno T. (2015)

RNA structure determination by solid-state NMR spectroscopy.

Nat Commun 6 doi:10.1038/ncomms8024
Europe PMC | doi

Simon B, Huart AS, Wilmanns M. (2015)

Molecular mechanisms of protein kinase regulation by calcium/calmodulin.

Bioorg. Med. Chem. doi:10.1016/j.bmc.2015.04.051
Europe PMC | doi


2014

Göbl C, Madl T, Simon B, Sattler M. (2014)

NMR approaches for structural analysis of multidomain proteins and complexes in solution.

Prog Nucl Magn Reson Spectrosc 80:26-63. doi:10.1016/j.pnmrs.2014.05.003
Europe PMC | doi

Dietl A, Wild K, Simon B. (2014)

¹H, ¹³C, and ¹⁵N chemical shift assignments of the phosphotyrosine binding domain 2 (PTB2) of human FE65

Biomol NMR Assign 8(1):93-95. doi:10.1007/s12104-013-9460-z
Europe PMC | doi


2013

Lapinaite A, Simon B, Skjaerven L, Rakwalska-Bange M, Gabel F, Carlomagno T. (2013)

The structure of the box C/D enzyme reveals regulation of RNA methylation

Nature 502(7472):519-523. doi:10.1038/nature12581
Europe PMC | doi

Dallmann A, Simon B, Duszczyk MM, Kooshapur H, Pardi A, Bermel W, Sattler M. (2013)

Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences

Angew. Chem. Int. Ed. Engl. 52(40):10487-10490. doi:10.1002/anie.201304391
Europe PMC | doi

Marchanka A, Simon B, Carlomagno T. (2013)

A suite of solid-state NMR experiments for RNA intranucleotide resonance assignment in a 21 kDa protein-RNA complex

Angew. Chem. Int. Ed. Engl. 52(38):9996-10001. doi:10.1002/anie.201304779
Europe PMC | doi

Carlomagno T, Amata I, Codutti L, Falb M, Fohrer J, Masiewicz P, Simon B. (2013)

Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme

J. Am. Chem. Soc. 135(11):4403-4411. doi:10.1021/ja311868t
Europe PMC | doi

Kang C, Ye H, Chia J, Choi BH, Dhe-Paganon S, Simon B, Schütz U, Sattler M, Yoon HS. (2013)

Functional role of the flexible N-terminal extension of FKBP38 in catalysis

Sci Rep 3:2985. doi:10.1038/srep02985
Europe PMC | doi


2012

Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. (2012)

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

Nat. Struct. Mol. Biol. 19(12):1257-1265. doi:10.1038/nsmb.2434
Europe PMC | doi


2011

Klug W, Dietl A, Simon B, Sinning I, Wild K. (2011)

Phosphorylation of LRP1 regulates the interaction with Fe65

FEBS Lett. 585(20):3229-3235. doi:10.1016/j.febslet.2011.09.028
Europe PMC | doi

Taylor M, Graw S, Sinagra G, Barnes C, Slavov D, Brun F, Pinamonti B, Salcedo EE, Sauer W, Pyxaras S, Anderson B, Simon B, Bogomolovas J, Labeit S, Granzier H, Mestroni L. (2011)

Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes

Circulation 124(8):876-885. doi:10.1161/circulationaha.110.005405
Europe PMC | doi

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M. (2011)

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF

Nature 475(7356):408-411. doi:10.1038/nature10171
Europe PMC | doi

Vojnic E, Mourão A, Seizl M, Simon B, Wenzeck L, Larivière L, Baumli S, Baumgart K, Meisterernst M, Sattler M, Cramer P. (2011)

Structure and VP16 binding of the Mediator Med25 activator interaction domain

Nat. Struct. Mol. Biol. 18(4):404-409. doi:10.1038/nsmb.1997
Europe PMC | doi

Simon B, Kirkpatrick JP, Eckhardt S, Reuter M, Rocha EA, Andrade-Navarro MA, Sehr P, Pillai RS, Carlomagno T. (2011)

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein

Structure 19(2):172-180. doi:10.1016/j.str.2010.11.015
Europe PMC | doi


2010

Falb M, Amata I, Gabel F, Simon B, Carlomagno T. (2010)

Structure of the K-turn U4 RNA: a combined NMR and SANS study

Nucleic Acids Res. 38(18):6274-6285. doi:10.1093/nar/gkq380
Europe PMC | doi

Stauch B, Simon B, Basile T, Schneider G, Malek NP, Kalesse M, Carlomagno T. (2010)

Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling

Angew. Chem. Int. Ed. Engl. 49(23):3934-3938. doi:10.1002/anie.201000140
Europe PMC | doi

Simon B, Madl T, Mackereth CD, Nilges M, Sattler M. (2010)

An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution

Angew. Chem. Int. Ed. Engl. 49(11):1967-1970. doi:10.1002/anie.200906147
Europe PMC | doi


2009

Bogomolovas J, Simon B, Sattler M, Stier G. (2009)

Screening of fusion partners for high yield expression and purification of bioactive viscotoxins

Protein Expr. Purif. 64(1):16-23. doi:10.1016/j.pep.2008.10.003
Europe PMC | doi

Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. (2009)

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19

EMBO J. 28(6):745-754. doi:10.1038/emboj.2009.7
Europe PMC | doi


2008

Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. (2008)

Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2

EMBO Rep. 9(11):1134-1140. doi:10.1038/embor.2008.188
Europe PMC | doi

Gabel F, Simon B, Nilges M, Petoukhov M, Svergun D, Sattler M. (2008)

A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints

J. Biomol. NMR 41(4):199-208. doi:10.1007/s10858-008-9258-y
Europe PMC | doi

Rumpf J, Simon B, Groemping Y, Sattler M. (2008)

1H, 13C, and 15N chemical shift assignments for the Eps15-EH2-stonin 2 complex

Biomol NMR Assign 2(1):55-58. doi:10.1007/s12104-008-9083-y
Europe PMC | doi

Rumpf J, Simon B, Jung N, Maritzen T, Haucke V, Sattler M, Groemping Y. (2008)

Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity

EMBO J. 27(3):558-569. doi:10.1038/sj.emboj.7601980
Europe PMC | doi


2006

Marino M, Zou P, Svergun D, Garcia P, Edlich C, Simon B, Wilmanns M, Muhle-Goll C, Mayans O. (2006)

The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin

Structure 14(9):1437-1447. doi:10.1016/j.str.2006.07.009
Europe PMC | doi

Gabel F, Simon B, Sattler M. (2006)

A target function for quaternary structural refinement from small angle scattering and NMR orientational restraints

Eur. Biophys. J. 35(4):313-327. doi:10.1007/s00249-005-0037-3
Europe PMC | doi

Edlich C, Simon B, Sattler M, Muhle-Goll C. (2006)

New NMR assignment 1H, 13C, and 15N assignment of the second PH domain of human pleckstrin (234-350)

J. Biomol. NMR 36 Suppl 1:21. doi:10.1007/s10858-005-6053-x
Europe PMC | doi

Kang CB, Ye H, Vivekanandan S, Simon B, Sattler M, Yoon HS. (2006)

Backbone 1H, 13C, and 15N resonance assignments of the N-terminal domain of FKBP38 (FKBP38NTD)

J. Biomol. NMR 36 Suppl 1:37. doi:10.1007/s10858-006-9001-5
Europe PMC | doi


2005

Lingel A, Simon B, Izaurralde E, Sattler M. (2005)

The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition

EMBO Rep. 6(12):1149-1155. doi:10.1038/sj.embor.7400583
Europe PMC | doi

Bottomley MJ, Stier G, Pennacchini D, Legube G, Simon B, Akhtar A, Sattler M, Musco G. (2005)

NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease

J. Biol. Chem. 280(12):11505-11512. doi:10.1074/jbc.m413959200
Europe PMC | doi


2004

Lingel A, Simon B, Izaurralde E, Sattler M. (2004)

NMR assignment of the Drosophila Argonaute2 PAZ domain

J. Biomol. NMR 29(3):421-422. doi:10.1023/b:jnmr.0000032513.15693.04
Europe PMC | doi

Lingel A, Simon B, Izaurralde E, Sattler M. (2004)

Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain

Nat. Struct. Mol. Biol. 11(6):576-577. doi:10.1038/nsmb777
Europe PMC | doi

Scheich C, Leitner D, Sievert V, Leidert M, Schlegel B, Simon B, Letunic I, Büssow K, Diehl A. (2004)

Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis

BMC Struct. Biol. 4:4. doi:10.1186/1472-6807-4-4
Europe PMC | doi

Simon B, Sattler M. (2004)

Speeding up biomolecular NMR spectroscopy

Angew. Chem. Int. Ed. Engl. 43(7):782-786. doi:10.1002/anie.200301680
Europe PMC | doi


2003

Lingel A, Simon B, Izaurralde E, Sattler M. (2003)

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

Nature 426(6965):465-469. doi:10.1038/nature02123
Europe PMC | doi

Holz C, Prinz B, Bolotina N, Sievert V, Büssow K, Simon B, Stahl U, Lang C. (2003)

Establishing the yeast Saccharomyces cerevisiae as a system for expression of human proteins on a proteome-scale

J. Struct. Funct. Genomics 4(2-3):97-108. doi:10.1023/a:1026226429429
Europe PMC | doi


2002

Simon B, Sattler M. (2002)

De novo structure determination from residual dipolar couplings by NMR spectroscopy

Angew. Chem. Int. Ed. Engl. 41(3):437-440. doi:10.1002/1521-3773(20020201)41:33.0.co;2-3
Europe PMC | doi


2001

Simon B, Zanier K, Sattler M. (2001)

A TROSY relayed HCCH-COSY experiment for correlating adenine H2/H8 resonances in uniformly 13C-labeled RNA molecules

J. Biomol. NMR 20(2):173-176. doi:10.1023/a:1011214914452
Europe PMC | doi


1998

Gryk MR, Abseher R, Simon B, Nilges M, Oschkinat H. (1998)

Heteronuclear relaxation study of the PH domain of beta-spectrin: restriction of loop motions upon binding inositol trisphosphate

J. Mol. Biol. 280(5):879-896. doi:10.1006/jmbi.1998.1731
Europe PMC | doi


1996

Simon B, Kimmich R, Kostler H. (1996)

Rotating-frame-imaging technique for spatially resolved diffusion and flow studies in the fringe field of RF probe coils

J MAGN RESON SER A 118:78-83.


1995

KIMMICH R, SIMON B, KOSTLER H. (1995)

MAGNETIZATION-GRID ROTATING-FRAME IMAGING TECHNIQUE FOR DIFFUSION AND FLOW MEASUREMENTS

J MAGN RESON SER A 112:7-12.