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Staff at EMBL

CP-60003342

Dr. Bernd Simon

NMR Facility Manager
Carlomagno Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

Total: 22 publication(s)

2014

Göbl C, Madl T, Simon B, Sattler M. (2014)
NMR approaches for structural analysis of multidomain proteins and complexes in solution.
Prog Nucl Magn Reson Spectrosc 80C:26-63. doi:10.1016/j.pnmrs.2014.05.003
Europe PMC | doi

Dietl A, Wild K, Simon B. (2014)
¹H, ¹³C, and ¹⁵N chemical shift assignments of the phosphotyrosine binding domain 2 (PTB2) of human FE65
Biomol NMR Assign 8(1):93-95. doi:10.1007/s12104-013-9460-z
Europe PMC | doi

Snaebjornsson M, Prior N, Bulusu V, Simon B, Carlomagno T, Aulehla A. (2014)
A role for central carbon metabolism in mammalian embryonic development?
Paper presented at the Metabolism, Diet and Disease 2014: Cancer and metabolism, Washington DC, USA, 28-30 May 2014.Cancer & metabolism 2(Suppl 1):P69. doi:10.1186/2049-3002-2-S1-P69
Europe PMC | doi


2013

Lapinaite A, Simon B, Skjaerven L, Rakwalska-Bange M, Gabel F, Carlomagno T. (2013)
The structure of the box C/D enzyme reveals regulation of RNA methylation
Nature 502(7472):519-523. doi:10.1038/nature12581
Europe PMC | doi

Marchanka A, Simon B, Carlomagno T. (2013)
A suite of solid-state NMR experiments for RNA intranucleotide resonance assignment in a 21 kDa protein-RNA complex
Angew. Chem. Int. Ed. Engl. 52(38):9996-10001. doi:10.1002/anie.201304779
Europe PMC | doi

Carlomagno T, Amata I, Codutti L, Falb M, Fohrer J, Masiewicz P, Simon B. (2013)
Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme
J. Am. Chem. Soc. 135(11):4403-4411. doi:10.1021/ja311868t
Europe PMC | doi

Kang C, Ye H, Chia J, Choi BH, Dhe-Paganon S, Simon B, Schütz U, Sattler M, Yoon HS. (2013)
Functional role of the flexible N-terminal extension of FKBP38 in catalysis
Sci Rep 3:2985. doi:10.1038/srep02985
Europe PMC | doi


2012

Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. (2012)
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
Nat. Struct. Mol. Biol. 19(12):1257-1265. doi:10.1038/nsmb.2434
Europe PMC | doi


2011

Klug W, Dietl A, Simon B, Sinning I, Wild K. (2011)
Phosphorylation of LRP1 regulates the interaction with Fe65
FEBS Lett. 585(20):3229-3235. doi:10.1016/j.febslet.2011.09.028
Europe PMC | doi

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M. (2011)
Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF
Nature 475(7356):408-411. doi:10.1038/nature10171
Europe PMC | doi

Simon B, Kirkpatrick JP, Eckhardt S, Reuter M, Rocha EA, Andrade-Navarro MA, Sehr P, Pillai RS, Carlomagno T. (2011)
Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein
Structure 19(2):172-180. doi:10.1016/j.str.2010.11.015
Europe PMC | doi


2010

Falb M, Amata I, Gabel F, Simon B, Carlomagno T. (2010)
Structure of the K-turn U4 RNA: a combined NMR and SANS study
Nucleic Acids Res. 38(18):6274-6285. doi:10.1093/nar/gkq380
Europe PMC | doi

Stauch B, Simon B, Basile T, Schneider G, Malek NP, Kalesse M, Carlomagno T. (2010)
Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling
Angew. Chem. Int. Ed. Engl. 49(23):3934-3938. doi:10.1002/anie.201000140
Europe PMC | doi

Simon B, Madl T, Mackereth CD, Nilges M, Sattler M. (2010)
An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution
Angew. Chem. Int. Ed. Engl. 49(11):1967-1970. doi:10.1002/anie.200906147
Europe PMC | doi


2009

Bogomolovas J, Simon B, Sattler M, Stier G. (2009)
Screening of fusion partners for high yield expression and purification of bioactive viscotoxins
Protein Expr. Purif. 64(1):16-23. doi:10.1016/j.pep.2008.10.003
Europe PMC | doi

Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. (2009)
Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19
EMBO J. 28(6):745-754. doi:10.1038/emboj.2009.7
Europe PMC | doi


2008

Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. (2008)
Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2
EMBO Rep. 9(11):1134-1140. doi:10.1038/embor.2008.188
Europe PMC | doi

Gabel F, Simon B, Nilges M, Petoukhov M, Svergun D, Sattler M. (2008)
A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints
J. Biomol. NMR 41(4):199-208. doi:10.1007/s10858-008-9258-y
Europe PMC | doi

Rumpf J, Simon B, Jung N, Maritzen T, Haucke V, Sattler M, Groemping Y. (2008)
Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity
EMBO J. 27(3):558-569. doi:10.1038/sj.emboj.7601980
Europe PMC | doi


2005

Lingel A, Simon B, Izaurralde E, Sattler M. (2005)
The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition
EMBO Rep. 6(12):1149-1155. doi:10.1038/sj.embor.7400583
Europe PMC | doi


2004

Lingel A, Simon B, Izaurralde E, Sattler M. (2004)
Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain
Nat. Struct. Mol. Biol. 11(6):576-577. doi:10.1038/nsmb777
Europe PMC | doi


2001

Simon B, Zanier K, Sattler M. (2001)
A TROSY relayed HCCH-COSY experiment for correlating adenine H2/H8 resonances in uniformly 13C-labeled RNA molecules
J. Biomol. NMR 20(2):173-176. doi:10.1023/a:1011214914452
Europe PMC | doi