Staff at EMBL

Sigrid Milles

Predoctoral Fellow
Lemke Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Publications

Facilitated aggregation of FG nucleoporins under molecular crowding conditions. Milles, S., Huy Bui, K., Koehler, C., Eltsov, M., Beck, M. & Lemke, E.A. EMBO Rep. 2013 Feb;14(2):178-83. doi: 10.1038/embor.2012.204. Epub 2012 Dec 14. PubMed

What precision-protein-tuning and nano-resolved single molecule sciences can do for each other. Milles, S. & Lemke, E.A. Bioessays. 2013 Jan;35(1):65-74. doi: 10.1002/bies.201200094. Epub 2012 Nov 13. PubMed

Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range. Milles, S., Koehler, C., Gambin, Y., Deniz, A.A. & Lemke, E.A. Mol Biosyst. 2012 Oct;8(10):2531-4. doi: 10.1039/c2mb25135c. PubMed

Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation. Borrmann, A., Milles, S., Plass, T., Dommerholt, J., Verkade, J.M., Wiessler, M., Schultz, C., van Hest, J.C., van Delft, F.L. & Lemke, E.A. Chembiochem. 2012 Sep 24;13(14):2094-9. doi: 10.1002/cbic.201200407. Epub 2012Sep 3. PubMed

Amino acids for diels-alder reactions in living cells. Plass, T., Milles, S., Koehler, C., Szymanski, J., Mueller, R., Wiessler, M., Schultz, C. & Lemke, E.A. Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4166-70. doi: 10.1002/anie.201108231.Epub 2012 Mar 30. PubMed

Click strategies for single-molecule protein fluorescence. Milles, S., Tyagi, S., Banterle, N., Koehler, C., Vandelinder, V., Plass, T., Neal, A.P. & Lemke, E.A. J Am Chem Soc. 2012 Mar 21;134(11):5187-95. Epub 2012 Mar 5. PubMed

Single molecule study of the intrinsically disordered FG-repeat nucleoporin 153. Milles, S. & Lemke, E.A. Biophys J. 2011 Oct 5;101(7):1710-9. doi: 10.1016/j.bpj.2011.08.025. PubMed

The Yeast Plasma Membrane ATP Binding Cassette (ABC) Transporter Aus1: PURIFICATION, CHARACTERIZATION, AND THE EFFECT OF LIPIDS ON ITS ACTIVITY. Marek, M., Milles, S., Schreiber, G., Daleke, D.L., Dittmar, G., Herrmann, A., Muller, P. & Pomorski, T.G. J Biol Chem. 2011 Jun 17;286(24):21835-43. Epub 2011 Apr 26. PubMed

Genetically encoded copper-free click chemistry. Plass, T., Milles, S., Koehler, C., Schultz, C. & Lemke, E.A. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3878-81. doi:10.1002/anie.201008178. Epub 2011 Mar 23. PubMed

Solubilization of protein aggregates by the acid stress chaperones HdeA and HdeB. Malki, A., Le, H.T., Milles, S., Kern, R., Caldas, T., Abdallah, J. & Richarme, G. J Biol Chem. 2008 May 16;283(20):13679-87. Epub 2008 Mar 20. PubMed