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Staff at EMBL

Noella Silva Martin

Postdoctoral Fellow (EIPOD)
Müller Group Bork Group

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

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Crystal structures of CbpF complexed with atropine and ipratropium reveal clues for the design of novel antimicrobials against Streptococcus pneumoniae. Silva-Martin, N., Retamosa, M.G., Maestro, B., Bartual, S.G., Rodes, M.J., Garcia, P., Sanz, J.M. & Hermoso, J.A. Biochim Biophys Acta. 2014 Jan;1840(1):129-35. doi: 10.1016/j.bbagen.2013.09.006.Epub 2013 Sep 11. Europe PMC

Promiscuous enantioselective (-)-gamma-lactamase activity in the Pseudomonas fluorescens esterase I. Torres, L.L., Schliessmann, A., Schmidt, M., Silva-Martin, N., Hermoso, J.A., Berenguer, J., Bornscheuer, U.T. & Hidalgo, A. Org Biomol Chem. 2012 May 7;10(17):3388-92. doi: 10.1039/c2ob06887g. Epub 2012Feb 22. Europe PMC

Crystal structures of bacterial peptidoglycan amidase AmpD and an unprecedented activation mechanism. Carrasco-Lopez, C., Rojas-Altuve, A., Zhang, W., Hesek, D., Lee, M., Barbe, S., Andre, I., Ferrer, P., Silva-Martin, N., Castro, G.R., Martinez-Ripoll, M., Mobashery, S. & Hermoso, J.A. J Biol Chem. 2011 Sep 9;286(36):31714-22. doi: 10.1074/jbc.M111.264366. Epub 2011Jul 20. Europe PMC

New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae. Garcia, M.T., Blazquez, M.A., Ferrandiz, M.J., Sanz, M.J., Silva-Martin, N., Hermoso, J.A. & de la Campa, A.G. J Biol Chem. 2011 Feb 25;286(8):6402-13. doi: 10.1074/jbc.M110.148148. Epub 2010Dec 17. Europe PMC

Crystallization and preliminary crystallographic analysis of the catalytic module of endolysin from Cp-7, a phage infecting Streptococcus pneumoniae. Silva-Martin, N., Molina, R., Angulo, I., Mancheno, J.M., Garcia, P. & Hermoso, J.A. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jun 1;66(Pt 6):670-3. doi:10.1107/S1744309110006718. Epub 2010 May 26. Europe PMC

Modification of pancreatic lipase properties by directed molecular evolution. Colin, D.Y., Deprez-Beauclair, P., Silva, N., Infantes, L. & Kerfelec, B. Protein Eng Des Sel. 2010 May;23(5):365-73. doi: 10.1093/protein/gzq008. Epub2010 Feb 11. Europe PMC

Crystallization and preliminary X-ray diffraction studies of the carbohydrate-recognition domain of SIGN-R1, a receptor for microbial polysaccharides and sialylated antibody on splenic marginal zone macrophages. Silva-Martin, N., Schauer, J.D., Park, C.G. & Hermoso, J.A. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt 12):1264-6.doi: 10.1107/S1744309109041992. Epub 2009 Nov 27. Europe PMC