Advanced Light Microscopy Facility
The Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools.
The facility was set up as a cooperation between EMBL and industry to improve communication between users and producers of high-end microscopy technology and to support in-house scientists and visitors in using light microscopy methods for their research. The ALMF also regularly organises in-house and international courses to teach basic and advanced light microscopy methods.
Major projects and accomplishments
- The ALMF presently manages 18 top-of-the-line microscope systems and eight high-content screening microscopes from leading industrial companies, as well as four image analysis workstations.
- More than 50 visitors per year come to carry out their own experiments in the ALMF or to evaluate microscopy equipment.
- The ALMF was the seed for the European Light Microscopy Initiative (ELMI) that establishes links with facilities throughout Europe.
- Usage of the facility has exceeded 50 000 hours per year.
- Assisting all EMBL groups and visitors through the microscopic imaging process: project planning, sample preparation, staining, microscope selection and use, image processing, presentation, data transfer and storage.
- Developing accessory software and microscopy equipment, co-developments with industrial partners, pre-evaluation of commercial equipment.
- Supporting all aspects of automated microscopy and high content screening projects, including RNAi technology.
The ALMF presently has collaborations with the following companies:
- Applied Precision*
- Carl Zeiss*
- Lambert Instruments*
- Leica Microsystems*
- Perkin Elmer*
- Scientific Volume Imaging
* The ALMF also serves as a reference site for these companies.