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Advanced Light Microscopy Facility

The Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools. The ALMF was set up as a cooperation between EMBL and industry to improve communication between users and producers of high-end microscopy technology and to support in-house scientists and visitors in using light microscopy methods for their research. The facility also organises regular international courses to teach advanced light microscopy methods.

Major projects and accomplishments

  • The ALMF presently manages 19 top-of-the-line microscope systems plus 9 High-Content Screening microscopes from leading industrial companies and five image analysis workstations.
  • More than 30 visitors per year come to carry out their own experiments in the ALMF or to evaluate microscopy equipment.
  • The ALMF was the seed for the European Light Microscopy Initiative (ELMI) that establishes links with light microscopy facilities throughout Europe.
  • Usage of the facility has exceeded 30,000 hours per year.

Services provided

  • Assisting all EMBL groups and visitors through the microscopic imaging process: project planning, sample preparation, staining, microscope selection and use, image processing, presentation, data transfer and storage.
  • Developing accessory software and microscopy equipment, co-developments with industrial partners, pre-evaluation of commercial equipment.
  • Facilitating automated microscopy and High Content Screening (HCS) projects.

Technology partners

The ALMF presently has collaborations with the following companies:

  • Applied Precision*
  • Bitplane*
  • Carl Zeiss*
  • Cell Biotrading*
  • Eppendorf*
  • Lambert Instruments*
  • Leica Microsystems*
  • Olympus Europe*
  • Perkin Elmer*
  • PicoQuant
  • Scientific Volume Imaging
  • Visitron*

* The ALMF also serves as a reference site for these companies.