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Staff at EMBL

CP-60002728

Dr. Beate Neumann

Senior Scientific Officer
Advanced Light Microscopy Facility

EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

E-mail: send a mail

Publications

Total: 22 publication(s)

2014

van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM. (2014)
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs
EMBO J. doi:10.15252/embj.201488202
Europe PMC | doi

Asteriti IA, Di Cesare E, De Mattia F, Hilsenstein V, Neumann B, Cundari E, Lavia P, Guarguaglini G. (2014)
The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy
Oncotarget 5(15):6229-6242.
Europe PMC


2013

Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W. (2013)
Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay
BMC Bioinformatics 14:308. doi:10.1186/1471-2105-14-308
Europe PMC | doi


2012

Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grøfte M, Bartkova J, Poulsen M, Oka Y, Bekker-Jensen S, Mailand N, Neumann B, Heriche JK, Shearer R, Saunders D, Bartek J, Lukas J, Lukas C. (2012)
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
Cell 150(4):697-709. doi:10.1016/j.cell.2012.06.039
Europe PMC | doi

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. (2012)
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
Nat. Cell Biol. 14(7):764-774. doi:10.1038/ncb2510
Europe PMC | doi

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J. (2012)
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1
Cell Death Differ. 19(5):798-807. doi:10.1038/cdd.2011.150
Europe PMC | doi

Stadler C, Hjelmare M, Neumann B, Jonasson K, Pepperkok R, Uhlén M, Lundberg E. (2012)
Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy
J Proteomics 75(7):2236-2251. doi:10.1016/j.jprot.2012.01.030
Europe PMC | doi

Casanova CM, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C. (2012)
Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation
PLoS ONE 7(9):e45943. doi:10.1371/journal.pone.0045943
Europe PMC | doi


2011

Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. (2011)
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases
Genome Res. 21(11):1955-1968. doi:10.1101/gr.116087.110
Europe PMC | doi

Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen RS, Grøfte M, Chan KL, Hickson ID, Bartek J, Lukas J. (2011)
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
Nat. Cell Biol. 13(3):243-253. doi:10.1038/ncb2201
Europe PMC | doi


2010

Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW. (2010)
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging
Nat. Methods 7(9):747-754. doi:10.1038/nmeth.1486
Europe PMC | doi

Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J. (2010)
High-throughput microscopy using live mammalian cells
Cold Spring Harb Protoc 2010(7):pdb.top84. doi:10.1101/pdb.top84
Europe PMC | doi

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J. (2010)
Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging
J. Struct. Biol. 170(1):1-9. doi:10.1016/j.jsb.2009.10.004
Europe PMC | doi

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. (2010)
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Nature 464(7289):721-727. doi:10.1038/nature08869
Europe PMC | doi


2008

Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R. (2008)
Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates
J Biomol Screen 13(7):575-580. doi:10.1177/1087057108320133
Europe PMC | doi

Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ. (2008)
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase
J. Cell. Sci. 121(Pt 10):1718-1726. doi:10.1242/jcs.019174
Europe PMC | doi

Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J. (2008)
A genome wide RNAI screen by time lapse microscopy in order to identify mitotic genes - Computational aspects and challenges
I S BIOMED IMAGING 328-331.


2007

Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R. (2007)
Reverse transfection on cell arrays for high content screening microscopy
Nat Protoc 2(2):392-399. doi:10.1038/nprot.2006.483
Europe PMC | doi


2006

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. (2006)
High-throughput RNAi screening by time-lapse imaging of live human cells
Nat. Methods 3(5):385-390. doi:10.1038/nmeth876
Europe PMC | doi

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. (2006)
Time-lapse microscopy-based genome wide RNAI screening in live human cells
I S BIOMED IMAGING 245-246.


2005

Sönnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Röder M, Finell J, Häntsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gönczy P, Coulson A, Hyman AA, Echeverri CJ. (2005)
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans
Nature 434(7032):462-469. doi:10.1038/nature03353
Europe PMC | doi


2004

Langner J, Neumann B, Goodman SL, Pawlita M. (2004)
RGD-mutants of B-lymphotropic polyomavirus capsids specifically bind to alpha(v)beta3 integrin
Arch. Virol. 149(10):1877-1896.
Europe PMC