The ALMF offers support for microscope automation.
In particular, we offer:
- Establishing automated acquisition protocols, including automated scanning of multi-well plates.
- Microscope experiments with online image analysis, where objects of interest are detected automatically and a complex acquisition protocol is launched for these objects.
To this end we have developed software interfaces between confocal microscopes (Leica SP5, Zeiss LSM 780) that establish a feedback loop between popular image analysis packages (Cellprofiler, FiJi, Cellcognition) and the microscope software. See example applications below.
- Experiments involving liquid handling on the microscope stage (e.g. adding a drug) using automated dispensing systems.