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ServicesHigh-Throughput Microscopy

Microscope Automation

Overview

The ALMF offers support for microscope automation. 

In particular, we offer:

  • Establishing automated acquisition protocols, including automated scanning of multi-well plates. 
  • Microscope experiments with online image analysis, where objects of interest are detected automatically and a complex acquisition protocol is launched for these objects.
    To this end we have developed software interfaces between confocal microscopes (Leica SP5, Zeiss LSM 780) that establish a feedback loop between popular image analysis packages (Cellprofiler, FiJi, Cellcognition)  and the microscope software. See example applications below.
  • Experiments involving liquid handling on the microscope stage (e.g. adding a drug) using automated dispensing systems.