Total: 13 publication(s)


Zacherl S, La Venuta G, Müller HM, Wegehingel S, Dimou E, Sehr P, Lewis JD, Erfle H, Pepperkok R, Nickel W. (2015)

A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.

J. Biol. Chem. 290(6):3654-3665. doi:10.1074/jbc.m114.590067
Europe PMC | doi


Bhuvanagiri M, Lewis J, Putzker K, Becker JP, Leicht S, Krijgsveld J, Batra R, Turnwald B, Jovanovic B, Hauer C, Sieber J, Hentze MW, Kulozik AE. (2014)

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

EMBO Mol Med 6(12):1509-1639. doi:10.15252/emmm.201404461
Europe PMC | doi


Pautus S, Sehr P, Lewis J, Fortuné A, Wolkerstorfer A, Szolar O, Guilligay D, Lunardi T, Décout JL, Cusack S. (2013)

New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain

J. Med. Chem. 56(21):8915-8930. doi:10.1021/jm401369y
Europe PMC | doi

Kesisova IA, Nakos KC, Tsolou A, Angelis D, Lewis J, Chatzaki A, Agianian B, Giannis A, Koffa MD. (2013)

Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules

PLoS ONE 8(3):e58485. doi:10.1371/journal.pone.0058485
Europe PMC | doi


Fueller F, Jehle B, Putzker K, Lewis JD, Krauth-Siegel RL. (2012)

High throughput screening against the peroxidase cascade of African trypanosomes identifies antiparasitic compounds that inactivate tryparedoxin

J. Biol. Chem. 287(12):8792-8802. doi:10.1074/jbc.m111.338285
Europe PMC | doi


Hose D, Rème T, Meissner T, Moreaux J, Seckinger A, Lewis J, Benes V, Benner A, Hundemer M, Hielscher T, Shaughnessy JD Jr, Barlogie B, Neben K, Krämer A, Hillengass J, Bertsch U, Jauch A, De Vos J, Rossi JF, Möhler T, Blake J, Zimmermann J, Klein B, Goldschmidt H. (2009)

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma

Blood 113(18):4331-4340. doi:10.1182/blood-2008-09-178350
Europe PMC | doi


Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Kraüsslich HG. (2008)

Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein

J. Biol. Chem. 283(46):32024-32033. doi:10.1074/jbc.m804230200
Europe PMC | doi

Guilligay D, Tarendeau F, Resa-Infante P, Coloma R, Crepin T, Sehr P, Lewis J, Ruigrok RW, Ortin J, Hart DJ, Cusack S. (2008)

The structural basis for cap binding by influenza virus polymerase subunit PB2

Nat. Struct. Mol. Biol. 15(5):500-506. doi:10.1038/nsmb.1421
Europe PMC | doi


Sehr P, Pawlita M, Lewis J. (2007)

Evaluation of different glutathione S-transferase-tagged protein captures for screening E6/E6AP interaction inhibitors using AlphaScreen

J Biomol Screen 12(4):560-567. doi:10.1177/1087057107301246
Europe PMC | doi

Polycarpou-Schwarz M, Müller K, Denger S, Riddell A, Lewis J, Gannon F, Reid G. (2007)

Thanatop: a novel 5-nitrofuran that is a highly active, cell-permeable inhibitor of topoisomerase II

Cancer Res. 67(9):4451-4458. doi:10.1158/0008-5472.can-07-0393
Europe PMC | doi

Lewis JD. (2007)

The role of the chemical biology core facility at EMBL: a vision for a European roadmap

ACS Chem. Biol. 2(1):21-23.
Europe PMC


Neduva V, Linding R, Su-Angrand I, Stark A, de Masi F, Gibson TJ, Lewis J, Serrano L, Russell RB. (2005)

Systematic discovery of new recognition peptides mediating protein interaction networks

PLoS Biol. 3(12):e405. doi:10.1371/journal.pbio.0030405
Europe PMC | doi

Boehringer D, Thermann R, Ostareck-Lederer A, Lewis JD, Stark H. (2005)

Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES

Structure 13(11):1695-1706. doi:10.1016/j.str.2005.08.008
Europe PMC | doi