Staff at EMBL
Devrim Acehan
Application Engineer
Electron Microscopy Core Facility
EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
| E-mail: | devrim.acehan@embl.de |
|---|
Publications
The physical state of lipid substrates provides transacylation specificity for tafazzin. Schlame, M., Acehan, D., Berno, B., Xu, Y., Valvo, S., Ren, M., Stokes, D.L. & Epand, R.M. Nat Chem Biol. 2012 Oct;8(10):862-9. PubMed
Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver. Ibrahim, J., Nguyen, A.H., Rehman, A., Ochi, A., Jamal, M., Graffeo, C.S., Henning, J.R., Zambirinis, C.P., Fallon, N.C., Barilla, R., Badar, S., Mitchell, A., Rao, R.S., Acehan, D., Frey, A.B. & Miller, G. Gastroenterology. 2012 Oct;143(4):1061-72. doi: 10.1053/j.gastro.2012.06.003.Epub 2012 Jun 12. PubMed
Tafazzin knockdown in mice leads to a developmental cardiomyopathy with early diastolic dysfunction preceding myocardial noncompaction. Phoon, C.K., Acehan, D., Schlame, M., Stokes, D.L., Edelman-Novemsky, I., Yu, D., Xu, Y., Viswanathan, N. & Ren, M. J Am Heart Assoc. 2012 Apr;1(2). pii: jah3-e000455. doi: 10.1161/JAHA.111.000455.Epub 2012 Apr 24. PubMed
Dendritic cells promote pancreatic viability in mice with acute pancreatitis. Bedrosian, A.S., Nguyen, A.H., Hackman, M., Connolly, M.K., Malhotra, A., Ibrahim, J., Cieza-Rubio, N.E., Henning, J.R., Barilla, R., Rehman, A., Pachter, H.L., Medina-Zea, M.V., Cohen, S.M., Frey, A.B., Acehan, D. & Miller, G. Gastroenterology. 2011 Nov;141(5):1915-26.e1-14. Epub 2011 Jul 27. PubMed
Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Acehan, D., Malhotra, A., Xu, Y., Ren, M., Stokes, D.L. & Schlame, M. Biophys J. 2011 May 4;100(9):2184-92. PubMed
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome. Acehan, D., Vaz, F., Houtkooper, R.H., James, J., Moore, V., Tokunaga, C., Kulik, W., Wansapura, J., Toth, M.J., Strauss, A. & Khuchua, Z. J Biol Chem. 2011 Jan 14;286(2):899-908. Epub 2010 Nov 9. PubMed
The dynamics of cardiolipin synthesis post-mitochondrial fusion. Xu, F.Y., McBride, H., Acehan, D., Vaz, F.M., Houtkooper, R.H., Lee, R.M., Mowat, M.A. & Hatch, G.M. Biochim Biophys Acta. 2010 Aug;1798(8):1577-85. Epub 2010 Apr 29. PubMed
Anisotropic self-assembly of spherical polymer-grafted nanoparticles. Akcora, P., Liu, H., Kumar, S.K., Moll, J., Li, Y., Benicewicz, B.C., Schadler, L.S., Acehan, D., Panagiotopoulos, A.Z., Pryamitsyn, V., Ganesan, V., Ilavsky, J., Thiyagarajan, P., Colby, R.H. & Douglas, J.F. Nat Mater. 2009 Apr;8(4):354-9. Epub 2009 Mar 22. PubMed
Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria. Acehan, D., Khuchua, Z., Houtkooper, R.H., Malhotra, A., Kaufman, J., Vaz, F.M., Ren, M., Rockman, H.A., Stokes, D.L. & Schlame, M. Mitochondrion. 2009 Apr;9(2):86-95. Epub 2008 Dec 11. PubMed
Plakoglobin is required for effective intermediate filament anchorage to desmosomes. Acehan, D., Petzold, C., Gumper, I., Sabatini, D.D., Muller, E.J., Cowin, P. & Stokes, D.L. J Invest Dermatol. 2008 Nov;128(11):2665-75. Epub 2008 May 22. PubMed
Comparative Electron Tomography of isolated Desmosomes. Owen G., Acehan D., Derr K., Rice W., Stokes D. 2008 Biochemical Society Transactions, 36, 173-179.
Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography. Acehan, D., Xu, Y., Stokes, D.L. & Schlame, M. Lab Invest. 2007 Jan;87(1):40-8. Epub 2006 Oct 16. PubMed
Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer. Yu, X., Wang, L., Acehan, D., Wang, X. & Akey, C.W. J Mol Biol. 2006 Jan 20;355(3):577-89. Epub 2005 Nov 8. PubMed
A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Yu, X., Acehan, D., Menetret, J.F., Booth, C.R., Ludtke, S.J., Riedl, S.J., Shi, Y., Wang, X. & Akey, C.W. Structure. 2005 Nov;13(11):1725-35. PubMed
Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Acehan, D., Jiang, X., Morgan, D.G., Heuser, J.E., Wang, X. & Akey, C.W. Mol Cell. 2002 Feb;9(2):423-32. PubMed