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Staff at EMBL

Devrim Acehan

Application Engineer
Electron Microscopy Core Facility

EMBL Heidelberg, Meyerhofstra├če 1, 69117 Heidelberg, Germany



A bacterial tubulovesicular network. Acehan, D., Santarella-Mellwig, R. & Devos, D.P. J Cell Sci. 2013 Nov 20. Europe PMC

The physical state of lipid substrates provides transacylation specificity for tafazzin. Schlame, M., Acehan, D., Berno, B., Xu, Y., Valvo, S., Ren, M., Stokes, D.L. & Epand, R.M. Nat Chem Biol. 2012 Oct;8(10):862-9. Europe PMC

Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver. Ibrahim, J., Nguyen, A.H., Rehman, A., Ochi, A., Jamal, M., Graffeo, C.S., Henning, J.R., Zambirinis, C.P., Fallon, N.C., Barilla, R., Badar, S., Mitchell, A., Rao, R.S., Acehan, D., Frey, A.B. & Miller, G. Gastroenterology. 2012 Oct;143(4):1061-72. doi: 10.1053/j.gastro.2012.06.003.Epub 2012 Jun 12. Europe PMC

Tafazzin knockdown in mice leads to a developmental cardiomyopathy with early diastolic dysfunction preceding myocardial noncompaction. Phoon, C.K., Acehan, D., Schlame, M., Stokes, D.L., Edelman-Novemsky, I., Yu, D., Xu, Y., Viswanathan, N. & Ren, M. J Am Heart Assoc. 2012 Apr;1(2). pii: jah3-e000455. doi: 10.1161/JAHA.111.000455.Epub 2012 Apr 24. Europe PMC

Dendritic cells promote pancreatic viability in mice with acute pancreatitis. Bedrosian, A.S., Nguyen, A.H., Hackman, M., Connolly, M.K., Malhotra, A., Ibrahim, J., Cieza-Rubio, N.E., Henning, J.R., Barilla, R., Rehman, A., Pachter, H.L., Medina-Zea, M.V., Cohen, S.M., Frey, A.B., Acehan, D. & Miller, G. Gastroenterology. 2011 Nov;141(5):1915-26.e1-14. Epub 2011 Jul 27. Europe PMC

Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Acehan, D., Malhotra, A., Xu, Y., Ren, M., Stokes, D.L. & Schlame, M. Biophys J. 2011 May 4;100(9):2184-92. Europe PMC

Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome. Acehan, D., Vaz, F., Houtkooper, R.H., James, J., Moore, V., Tokunaga, C., Kulik, W., Wansapura, J., Toth, M.J., Strauss, A. & Khuchua, Z. J Biol Chem. 2011 Jan 14;286(2):899-908. Epub 2010 Nov 9. Europe PMC

The dynamics of cardiolipin synthesis post-mitochondrial fusion. Xu, F.Y., McBride, H., Acehan, D., Vaz, F.M., Houtkooper, R.H., Lee, R.M., Mowat, M.A. & Hatch, G.M. Biochim Biophys Acta. 2010 Aug;1798(8):1577-85. Epub 2010 Apr 29. Europe PMC

Anisotropic self-assembly of spherical polymer-grafted nanoparticles. Akcora, P., Liu, H., Kumar, S.K., Moll, J., Li, Y., Benicewicz, B.C., Schadler, L.S., Acehan, D., Panagiotopoulos, A.Z., Pryamitsyn, V., Ganesan, V., Ilavsky, J., Thiyagarajan, P., Colby, R.H. & Douglas, J.F. Nat Mater. 2009 Apr;8(4):354-9. Epub 2009 Mar 22. Europe PMC

Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria. Acehan, D., Khuchua, Z., Houtkooper, R.H., Malhotra, A., Kaufman, J., Vaz, F.M., Ren, M., Rockman, H.A., Stokes, D.L. & Schlame, M. Mitochondrion. 2009 Apr;9(2):86-95. Epub 2008 Dec 11. Europe PMC

Plakoglobin is required for effective intermediate filament anchorage to desmosomes. Acehan, D., Petzold, C., Gumper, I., Sabatini, D.D., Muller, E.J., Cowin, P. & Stokes, D.L. J Invest Dermatol. 2008 Nov;128(11):2665-75. Epub 2008 May 22. Europe PMC

Cryoelectron tomography of isolated desmosomes. Owen, G.R., Acehan, D., Derr, K.D., Rice, W.J. & Stokes, D.L. Biochem Soc Trans. 2008 Apr;36(Pt 2):173-9. doi: 10.1042/BST0360173. Europe PMC

Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography. Acehan, D., Xu, Y., Stokes, D.L. & Schlame, M. Lab Invest. 2007 Jan;87(1):40-8. Epub 2006 Oct 16. Europe PMC

Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer. Yu, X., Wang, L., Acehan, D., Wang, X. & Akey, C.W. J Mol Biol. 2006 Jan 20;355(3):577-89. Epub 2005 Nov 8. Europe PMC

A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Yu, X., Acehan, D., Menetret, J.F., Booth, C.R., Ludtke, S.J., Riedl, S.J., Shi, Y., Wang, X. & Akey, C.W. Structure. 2005 Nov;13(11):1725-35. Europe PMC

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Acehan, D., Jiang, X., Morgan, D.G., Heuser, J.E., Wang, X. & Akey, C.W. Mol Cell. 2002 Feb;9(2):423-32. Europe PMC