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EMBO Conference Series

Microtubules - Structure, Regulation and Functions

EMBL Heidelberg, Germany Wednesday 2 June - Saturday 5 June 2010
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Programme

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Day One: Wednesday 2 June 2010

10.00 -12.30 Registration
12.30 - 14.00 BUFFET (ATC Foyer)
14.00 - 14.15 Welcome and Opening Remarks
  Session : MTs in Cell Division 1
14.15 - 16.00 Session Chair: Andrea Musacchio
14.15 - 14.40 Andrea Musacchio
  Molecular bais of feddback control at the kinetochore-microtubule interface
14.40 - 15.05 Alexey Khodjakov
  Typical kinetochore behaviour in human cells
15.05 - 15.30 Charles L. Asbury
  New strategies for uncovering how chromosomes are moved during mitosis
15.30 - 16.00 Patricia Wadsworth
  Dynamics of GFP Eg5 in the Mammalian Spindle
15.45 - 16.00 Alexander Bird
  Aurora A dependent recruitment of TACC3 to spindles reveals a comples containing clathrin and a novel + TIP
16.00 - 16.35 COFFEE BREAK (ATC Foyer)
  Session : MT Organisation I
16.35 - 18.05 Session Chair: Gohta Goshima
16.35 - 17.00 Pavel Draber
  Regulation of microtubule formation in activated mast cells
17.00 - 17.25 Gotha Goshima
  Mechanisms of microtubule nucleation and growth in cells
17.25 - 17.50 François Nédélec
  Microtubule organisation in Xenopus meiotic spindles
17.50 - 18.05 Johanna Höög
  A cellular corset: the sub pellicular microtubule array of the kinetoplastids
18.05 - 19.35 DINNER (EMBL Canteen)
19.35 - 20.35 Keynote Lecture: Timothy J. Mitchison
  How does a large cells find its center?
  Get together - beer and wine reception (ATC Lounge/ Helix A)

Day Two: Thursday 3 June 2010

  Session: MT Structure
09.00 - 10.45 Session Chair: Andreas Hoenger
09.00 - 09.25 David A. Agard
  Gamma tubulin complexes and the mechanisms of microtubule formation
09.25 - 09.50 Andreas Hoenger
  3D Cryo Electron Tomography Studies on Microtubule - MAP interactions in vitro and in situ
09.50 - 10.15 Claude Antony
  Microtubule Network 3D Reconstructions in Yeasts
10.15 - 10.30 Marcel Knossow
  The tubulin structural, nucleotide and microtubule assembly cycles
10.30 - 10.45 Carolyn Moores
  8Å structure of MAP stablized microtubules
10.45 - 11.00 COFFEE BREAK (ATC Foyer)
  Session: MT Regulators I
11.10 - 12.40 Session Chair: Carsten Janke
11.10 - 11.35 Didier Job
  Toward a functional and molecular understanding of the tubulin tyrosination cycle
11.35 - 12.00 Linda Wordeman
  Catalysis of the microtubule on rate is the major parameter regulating the depolymerase activity of MCAK
12.00 - 12.35 Carsten Janke
  Enzymatic mechanism and functions of tubulin polyglutamylation and polyglycylation
12.25 - 12.40 Jose Andreu
  Stathmin and interfacial microtubule inhibitors recognise a naturally curved conformation of tubulin dimers
12.40 - 14.00 LUNCH (ATC Foyer)
14.00 - 16.00 POSTER SESSION I (odd numbers - ATC Helix A)
  Session: MTs in Differentiation and Development I
16.00 - 17.30 Session Chair: Renata Basto
16.00 - 16.25 Peter Baas
  Mitotic motor proteins regulate microtubule behaviours during the growth and navigation of the axon
16.25 - 16.50 Renata Basto
  Investigating the role of the MT associated protein ASP in asymmetric cell division and neurogenesis
16.50 - 17.15 Gregg G. Gundersen
  Microtubule capture mechanisms in migrating cells
17.15 - 17.30 Krzysztof Rogowski
  A family of protein deglutamylating enzymes associated with neurodegeneration
17.30 Buses to Heidelberg/ Beer & snacks poster session (ATC Helices)
18.30 - 20.00 DINNER (EMBL Canteen)

Day Three: Friday 4 June 2010

  Session: MT + TIPs
09.00 - 10.45 Session Chair: Michel Steinmetz
09.00 - 09.25 Anna Akhmanova
  Functional analysis of microtubule plus end binding proteins
09.25 - 09.50 Torsten Wittmann
  Phosphoregulation and function of CLASP proteins
09.50 - 10.15 Michel Steinmetz
  Molecular basis of EB mediated microtubule tip tracking
10.15 - 10.30 Marvin Tanenbaum
  Regulation of microtubule dynamics by the novel plus end tracking kinesin Kifl8b
10.30 - 10.45 Roman Koning
  Cryo electron tomography on cellular microtubule plus ends
10.45 - 11.10 COFFEE BREAK (ATC Foyer)
  Session: MTs in Cell Division II
11.10 - 12.40 Session Chair: Rebecca Heald
11.10 - 11.35 Daniel W. Gerlich
  Microtubule and membrane dynamics during cytokinetic abscission
11.35 - 12.00 Rebecca Heald
  Katanin mediated interspecies spindle length scaling in Xenopus
12.00 - 12.25 Arshad Desai
  A Kinetochore Independent Mechanism Drives Anaphase Chromosome Separation during Acentrosomal Meiosis
12.25 - 12.40 Stefan Westermann
  Reconstitution of kinetochore microtubule interactions in vivo and in vitro
12.40 - 14.00 LUNCH (ATC Foyer)
14.00 - 16.00 POSTER SESSION II (even numbers/ ATC Helix B)
  Session: MT Organisation II
16.00 - 17.30 Session Chair: Thomas Surrey
16.00 - 16.25 Marileen Dogterom
  Regulation of microtubule (aster) dynamics by 'cortical' dynein
16.25 - 16.50 Robert A. Cross
  Motorized self organisation of S. pombe microtubules
16.50 - 17.15 Thomas Surrey
  How mitotic kinesins and antiparallel bundlers determine microtubule organisation and dynamics
17.15 - 17.30 Gero Fink
  Ase1 brakes kinesin 14 driven microtubule sliding in vitro
17.30 - 18.00 COFFEE BREAK (ATC Foyer)
  Session: MT Regulators II
18.00 - 19.30 Session Chair: Franck Perez
18.00 - 18.25 Franck Perez
  CLIP 170, GTP tubulin and the regulation of microtubule dynamic instability
18.25 - 18.50 Isabelle Arnal
  Structural basis of the interaction between microtubules and +TIPs
18.50 - 19.15 Jonathon Howard
  Regulation of Microtubule Dynamice by Depolymerizing Kinesins and Polymerases
19.15 - 19.30 Jennifer Ross
  Single Molecule Studies of Microtubule Severing Enzymes
19.40 - 23.30 BBQ and Party (EMBL Canteen and Terrace)

Day Four: Saturday 5 June 2010

  Session: MT Organisation III
09.00 - 10.30 Session Chair: Kenneth E. Sawin
09.00 - 09.25 Matthiew Piel
  Mechanotransduction during mitosis: how external forces affect dividing cells
09.25 - 09.50 Kenneth E. Sawin
  Organising microtubule organisers
09.50 - 10.15 David Odde
  Kinetics of Microtubule Assembly
10.15 - 10.30 Marylin Vantard
  Molecular analysis of the microtubule bundling activity of the mitotic microtubule associated protein, AtMAP65 4
10.30 - 11.00 COFFEE BREAK (ATC Foyer)
  SESSION: MTs in Differentiation and Development II
11.00 - 12.45 Session Chair: Anne Ephrussi
11.00 - 11.25 Damian Brunner
  Microtubule mediated membrane organisation and cell polarity
11.25 - 11.50 Kristen Verhey
  Ran, importins, and ciliary targeting of kinesin motors
11.50 - 12.15 Anne Ephrussi
  Microtubules and motors in oskar RNP transport
12.15 - 12.30 Niels Galjart
  A role for the microtubule plus end tracking protein CLASP2 in hematopoietic stem cell maintenance
12.30 - 12.45 Lukas Kapitein
  Mixed microtubules steer dynein driven cargo transport into dendrites
12.45 - 14.00 LUNCH (EMBL Canteen)
  Hot Topics Session
14.00 - 15.30 Session Chair: Ronald D. Vale
14.00 - 14.15 Babet van der Vaart
  SLAIN1 and SLAIN2 are novel microtubule plus end tracking proteins that control microtubule growth in interphase
14.15 - 14.30 Sarah Goodwin
  Patronin Regulates the Microtubule Network by Protecting Microtubule Minus Ends
14.30 - 14.45 Remigio Picone
  A polarised population of dynamic microtubules mediates homeostatic length control in animal cells
14.45 - 15.00 Isa Rishal
  Microtubule Motors in Cell Size Sensing
15.00 - 15.15 Johanna Roostalu
  Biochemical Characterisation of Cin8, the Kinesin 5 of Saccharomyces cerevisiae
15.15 - 15.30 Mamta Amrute
  A novel in vitro assay provides evidence that microtubule motor copy number controls differential mRNA sorting
15.30 - 16.00 COFFEE BREAK (ATC Foyer)
  Session: MT motors
16.00 - 17.30 Session Chair: Michio Tomishige
16.00 - 16.25 Stan A. Burgess
  Structure and mechanism of the microtubule motor dynein
16.25 - 16.50 Michio Tomishige
  Structural basis for the coordinated processive movement of kinesin
16.50 - 17.15 Ronald D. Vale
  New microtubule associated proteins involved in mitosis
17.15 - 17.30 Masanori Mishima
  14-3-3 and Aurora B cooperately regulates the clustering of the centralspindlin kinesin-6/RhoGAP complex that is essential for its accumulation to the spindle midzone during cytokinesis
17.30 - 17.40 Closing Remarks, feedback on conference, proposals for 2012 conference
   
   
   

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