Top image

EMBO Conference Series

Chemical Biology 2012

EMBL Heidelberg, Germany Wednesday 26 September - Saturday 29 September 2012 Registration closed
Abstract submission closed
context.title

Download Poster

Programme

 

Day 1 - Wednesday, 26 September 2012
11:30 - 13:30 Registration
13:30 - 13:40 Opening Words: Maja Köhn, John Overington, Carsten Schultz
13:40 - 17:10 Session 1: Chemical (Gen)omics
Chair: Maja Köhn
13:40 - 14:15 The dynamics of RNA as key to understanding gene regulation mediated by mRNA riboswitches

Ronald Micura, Leopold Franzens University, Austria

14:15 - 14:50 Examining mechanisms of drug action and resistance

Tarun Kapoor, The Rockefeller University, USA

14:50 - 15:25

Selective chemical activation of Protein Phosphatase-1: A novel approach to therapy?
Maja Köhn, EMBL Heidelberg, Germany

15:25 - 15:45 Coffee Break
15:45 - 16:20 Synthesis of complex and diverse compounds leads to a novel anticancer agent
Paul J. Hergenrother, The University of Illinois at Urbana-Champaign, USA
16:20 - 16:55 Turning Enzymes ON with small molecules

James A. Wells, University of California at San Francisco, USA

16:55 - 17:10 Short Talk: Steven Verhelst, Technical University Munich, Germany
17:10 - 17:25 Short Talk: Daniel Abankwa, Abo Akademi University, Finland
17:25 - 17:40 Short Talk: Sascha Hoogendoorn, Leiden University, The Netherlands
17:40 - 18:30 Light Dinner and Poster Preview Session
18:30 - 19:30 Keynote Session - Chair: Maja Köhn
Molecular Logic and Enzymatic Machinery in Natural Product Biosynthesis

Christopher T. Walsh, Harvard Medical School, USA

  - Free Evening -
 
 
Day 2 - Thursday, 27 September 2012
09:00 - 12:00 Session 2: Peptide and Protein Engineering

Chair: Edward Lemke

09:00 - 09:35 Reprogramming the Genetic Code

Jason W. Chin, Medical Research Council Laboratory of Molecular Biology, United Kingdom

09:35 - 10:10 Chemical modification of peptides and proteins to improve function and biostability
Annette G. Beck-Sickinger, University of Leipzig, Germany
10:10 - 10:25 Short Talk: Lisa Pollaro, EPFL, Switzerland
10:25 - 10:55 Coffee Break
10:55 - 11:30 Bioinspired Chemistry with Peptides – Asymmetric Catalysis and  Silver Nanoparticles

Helma Wennemers, Swiss Federal Institute of Technology Zurich, Switzerland

11:30 - 11:45 Short Talk: Dirk Schwarzer, University of Tuebingen, Germany
   
12:00 - 13:30 Lunch
13:30 - 14:55 Session 3: Peptide and Protein Engineering / Chemical Cell Biology
Chair: Annette Beck-Sickinger
13:30 - 14:05 Non-Canonical Amino Acids in the Interrogation of Cellular Protein Synthesis

David A. Tirrell, California Institute of Technology, USA

14:05 - 14:40 Visualizing information transfer through the plasmamembrane

Alanna Schepartz, Yale University, USA

14:40 - 14:55 Short Talk: Chiaki Ito, Tohoku University, Japan
14:55 - 15:10 Short Talk: Remigiusz Serwa, Imperial College London, United Kingdom
15:10 - 15:25 Short Talk: Kurt Deshayes, Genentech Inc, United States of America
15:25 - 16:30 Meet the Speakers Session 1 incl. Coffee Break
16:30 - 19:00 Poster Session 1 incl. Snacks kindly sponsored by Sanofi Aventis
19:00 - 20:00 Keynote Session - Chair: Peter Gölitz

Molecular Recognition in Water, and the Hydrophobic Effect
George M. Whitesides, Harvard University, USA

  - Free Evening -
 
 
Day 3 - Friday, 28 September 2012
09:00 - 12:00 Session 4: Synthetic/Computational Methods
Chair: Rolf Breinbauer
09:00 - 09:35 Substrate activity screening: A fragment-based method for inhibitor discovery

Jonathan Ellman, Yale University, USA

09:35 - 09:50 Short Talk: Dmitri Filippov, Leiden Institute of Chemistry, The Netherlands
09:50 - 10:05 Short Talk: Swen Hölder, The Institute of Cancer Research, United Kingdom
10:05 - 10:35 Coffee Break
10:35 - 11:10 The Chemical Basis of Pharmacology

Brian Shoichet, University of California at San Francisco, USA

11:10 - 11:45 Systems chemical analysis of adverse drug reactions extracted from electronic patient records

Søren Brunak, Technical University of Denmark and University of Copenhagen, Denmark

11:45 - 12:00 Short Talk: Steffen Renner, Novartis, Switzerland
12:00 - 13:30 Lunch
13:30 - 15:30 Session 5: Drug Discovery
Chair: John Overington
13:30 - 14:05 To be announced

John Overington, EBML-EBI, United Kingdom

14:05 - 14:40

EU-OPENSCREEN – Building a European Resource and Infrastructure to support Chemical Biology Research
Ronald Frank, Leibniz Institute for Molecular Pharmacology, Germany

14:40 - 15:15 Does Medicinal Chemistry Have A Future?

Derek Lowe, Vertex Pharmaceuticals, USA

15:15 - 15:30 Short Talk: Anders Nielsen, Novo Nordisk A/S, Denmark
15:30 - 16:30 Meet the Speakers Session 2 incl. Coffee Break
16:30 - 19:00 Poster Session 2 incl. Snacks
19:00 - 20:00 Keynote Session - Chair: John Overington
Integrating discovery of chemical tools and drugs for cancer
Paul Workman, The Institute of Cancer Research, United Kingdom
20:00 - 24:00 Dinner & Party
 

 

Day 4 - Saturday, 29 September 2012
09:00 - 12:25 Session 6: Molecular Imaging and Switching Tools
Chair: Carsten Schultz
09:00 - 09:35 Modular engineering of protein switches

Maarten Merkx, Eindhoven University of Technology, The Netherlands

09:35 - 10:10 Chemical approaches for control and analysis of biological processes

Ludovic Jullien, École Normale Supérieure Paris, France

10:10 - 10:25 Short Talk: Stephen Miller, University of Massachusetts Medical School, United States of America
10:25 - 10:45 Coffee Break
10:45 - 11:20 The ins and outs of developing fluorescent probes for live cell imaging
Amy E. Palmer, University of Colorado, USA
11:20 - 11:55 Understanding the language of protein post-translational modifications

Philip A. Cole,  Johns Hopkins University School of Medicine, USA

11:55 - 12:10 Short Talk: Luke Lavis, Janelia Farm Research Campus/HHMI, United States of America
12:10 - 12:25 Short Talk: Anna Rutkowska, EMBL Heidelberg, Germany
12:25 - 13:00 Coffee Break with Lunch Packages
13:00 - 14:00 Keynote Session - Chair: Carsten Schultz
The spatial organization of Ras proto-oncogene products
Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany
14:00 - 14:10 Closing Remarks