EMBO Conference Series
Chemical Biology 2012
EMBL Heidelberg, Germany Wednesday 26 September - Saturday 29 September 2012 Registration closedAbstract submission closed
Programme
| 11:30 - 13:30 | Registration |
|---|---|
| 13:30 - 13:40 | Opening Words: Maja Köhn, John Overington, Carsten Schultz |
| 13:40 - 17:10 | Session 1: Chemical (Gen)omics Chair: Maja Köhn |
| 13:40 - 14:15 |
The dynamics of RNA as key to understanding gene regulation mediated by mRNA riboswitches
Ronald Micura, Leopold Franzens University, Austria |
| 14:15 - 14:50 |
Examining mechanisms of drug action and resistance
Tarun Kapoor, The Rockefeller University, USA |
| 14:50 - 15:25 |
Selective chemical activation of Protein Phosphatase-1: A novel approach to therapy? |
| 15:25 - 15:45 | Coffee Break |
| 15:45 - 16:20 | Synthesis of complex and diverse compounds leads to a novel anticancer agent Paul J. Hergenrother, The University of Illinois at Urbana-Champaign, USA |
| 16:20 - 16:55 |
Turning Enzymes ON with small molecules
James A. Wells, University of California at San Francisco, USA |
| 16:55 - 17:10 | Short Talk: Steven Verhelst, Technical University Munich, Germany |
| 17:10 - 17:25 | Short Talk: Daniel Abankwa, Abo Akademi University, Finland |
| 17:25 - 17:40 | Short Talk: Sascha Hoogendoorn, Leiden University, The Netherlands |
| 17:40 - 18:30 | Light Dinner and Poster Preview Session |
| 18:30 - 19:30 |
Keynote Session - Chair: Maja Köhn Molecular Logic and Enzymatic Machinery in Natural Product Biosynthesis Christopher T. Walsh, Harvard Medical School, USA |
| - Free Evening - |
| 09:00 - 12:00 |
Session 2: Peptide and Protein Engineering
Chair: Edward Lemke |
|---|---|
| 09:00 - 09:35 |
Reprogramming the Genetic Code
Jason W. Chin, Medical Research Council Laboratory of Molecular Biology, United Kingdom |
| 09:35 - 10:10 | Chemical modification of peptides and proteins to improve function and biostability Annette G. Beck-Sickinger, University of Leipzig, Germany |
| 10:10 - 10:25 | Short Talk: Lisa Pollaro, EPFL, Switzerland |
| 10:25 - 10:55 | Coffee Break |
| 10:55 - 11:30 |
Bioinspired Chemistry with Peptides – Asymmetric Catalysis and Silver Nanoparticles
Helma Wennemers, Swiss Federal Institute of Technology Zurich, Switzerland |
| 11:30 - 11:45 | Short Talk: Dirk Schwarzer, University of Tuebingen, Germany |
| 12:00 - 13:30 | Lunch |
| 13:30 - 14:55 | Session 3: Peptide and Protein Engineering / Chemical Cell Biology Chair: Annette Beck-Sickinger |
| 13:30 - 14:05 |
Non-Canonical Amino Acids in the Interrogation of Cellular Protein Synthesis
David A. Tirrell, California Institute of Technology, USA |
| 14:05 - 14:40 |
Visualizing information transfer through the plasmamembrane
Alanna Schepartz, Yale University, USA |
| 14:40 - 14:55 | Short Talk: Chiaki Ito, Tohoku University, Japan |
| 14:55 - 15:10 | Short Talk: Remigiusz Serwa, Imperial College London, United Kingdom |
| 15:10 - 15:25 | Short Talk: Kurt Deshayes, Genentech Inc, United States of America |
| 15:25 - 16:30 | Meet the Speakers Session 1 incl. Coffee Break |
| 16:30 - 19:00 | Poster Session 1 incl. Snacks kindly sponsored by Sanofi Aventis |
| 19:00 - 20:00 |
Keynote Session - Chair: Peter Gölitz
Molecular Recognition in Water, and the Hydrophobic Effect |
| - Free Evening - |
| 09:00 - 12:00 | Session 4: Synthetic/Computational Methods Chair: Rolf Breinbauer |
|---|---|
| 09:00 - 09:35 |
Substrate activity screening: A fragment-based method for inhibitor discovery
Jonathan Ellman, Yale University, USA |
| 09:35 - 09:50 | Short Talk: Dmitri Filippov, Leiden Institute of Chemistry, The Netherlands |
| 09:50 - 10:05 | Short Talk: Swen Hölder, The Institute of Cancer Research, United Kingdom |
| 10:05 - 10:35 | Coffee Break |
| 10:35 - 11:10 |
The Chemical Basis of Pharmacology
Brian Shoichet, University of California at San Francisco, USA |
| 11:10 - 11:45 |
Systems chemical analysis of adverse drug reactions extracted from electronic patient records
Søren Brunak, Technical University of Denmark and University of Copenhagen, Denmark |
| 11:45 - 12:00 | Short Talk: Steffen Renner, Novartis, Switzerland |
| 12:00 - 13:30 | Lunch |
| 13:30 - 15:30 | Session 5: Drug Discovery Chair: John Overington |
| 13:30 - 14:05 |
To be announced
John Overington, EBML-EBI, United Kingdom |
| 14:05 - 14:40 |
EU-OPENSCREEN – Building a European Resource and Infrastructure to support Chemical Biology Research |
| 14:40 - 15:15 |
Does Medicinal Chemistry Have A Future?
Derek Lowe, Vertex Pharmaceuticals, USA |
| 15:15 - 15:30 | Short Talk: Anders Nielsen, Novo Nordisk A/S, Denmark |
| 15:30 - 16:30 | Meet the Speakers Session 2 incl. Coffee Break |
| 16:30 - 19:00 | Poster Session 2 incl. Snacks |
| 19:00 - 20:00 | Keynote Session - Chair: John Overington Integrating discovery of chemical tools and drugs for cancer Paul Workman, The Institute of Cancer Research, United Kingdom |
| 20:00 - 24:00 | Dinner & Party |
| 09:00 - 12:25 | Session 6: Molecular Imaging and Switching Tools Chair: Carsten Schultz |
|---|---|
| 09:00 - 09:35 |
Modular engineering of protein switches
Maarten Merkx, Eindhoven University of Technology, The Netherlands |
| 09:35 - 10:10 |
Chemical approaches for control and analysis of biological processes
Ludovic Jullien, École Normale Supérieure Paris, France |
| 10:10 - 10:25 | Short Talk: Stephen Miller, University of Massachusetts Medical School, United States of America |
| 10:25 - 10:45 | Coffee Break |
| 10:45 - 11:20 | The ins and outs of developing fluorescent probes for live cell imaging Amy E. Palmer, University of Colorado, USA |
| 11:20 - 11:55 |
Understanding the language of protein post-translational modifications
Philip A. Cole, Johns Hopkins University School of Medicine, USA |
| 11:55 - 12:10 | Short Talk: Luke Lavis, Janelia Farm Research Campus/HHMI, United States of America |
| 12:10 - 12:25 | Short Talk: Anna Rutkowska, EMBL Heidelberg, Germany |
| 12:25 - 13:00 | Coffee Break with Lunch Packages |
| 13:00 - 14:00 | Keynote Session - Chair: Carsten Schultz The spatial organization of Ras proto-oncogene products Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany |
| 14:00 - 14:10 | Closing Remarks |
