Location & dates EMBL Heidelberg, Germany 17 - 21 Oct 2012
Deadlines Registration closed Abstract - submission closed



DAY 1 Wednesday 17 October 2012
Time Topic
16:00-18:00 Arrival and Registration
18:00-18:15 Opening Ceremony
18:15-20:15 Opening Session:

Chair: Michael Knop, Zentrum für Molekulare Biologie in Heidelberg (ZMBH), Germany

18.15-18:45 Evolvability in Sequence Space

Dan Hartl, Harvard University, USA  

18:45-19:15 Effects of aneuploidy in tumorigenesis

Angelika Amon, MIT, USA  

19:15-19:45 Hidden layers of transcriptome complexity

Lars Steinmetz, EMBL Heidelberg, Germany  

19:45 Dinner
  Welcome Reception



DAY 2 Thursday 18 October 2012
Time Topic
09:00-12:40 Session 1:

Chair: Kevin Verstrepen, University of Leuven, Belgium

09:00-09:30 Synthesis and scrambling of the yeast genome: generation of phenotype diversity

Jef Boeke, John Hopkins University, USA

09:30-10:00 Generations of meiotic instability in natural and experimental hybrids: Microbotryum as a model

Michael Hood, Amherst College, USA

10:00-10:30 The evolution of wine yeast strains: A model for the study of domestication?

Florian Bauer, University of Stellenbosch, South Africa 

10:30-11:00 Coffee Break
11:00-11:30 Evolving digital organisms to unravel the roots of genome architecture

Guillaume Beslon, CNRS, France

11:30-11:50 Dispersal of a carnivorous pitcher plant yeast over time and space

Primrose Boynton, MPI of Evolutionary Biology, Germany

11:50-12:10 Why is Candida glabrata a haploid yeast while its relatives are diploids?

Jure Piskur, Lund University, Sweden

12:10-12:40 Evolutionary rescue in experimental populations of microbes

Graham Bell, McGill University, Canada

12:40-14:00 Lunch
14:00-16:00  POSTER SESSION I

Helix A (poster numbers 25 – 75)

16:00-19:20 Session 2:

Chair: Bernard Dujon, Institut Pasteur, CNRS and University P & M Curie, France

16:00-16:30 High-throughput, High-resolution mapping, characterization, and optimization of replication origins in diverse yeasts

Maitreya Dunham, University of Washington, USA  

16:30-17:00 Competition and cooperation within yeast colonies

Melanie Mueller & Andrew Murray, Harvard University, USA

17:00-17:30 The transient evolutionary role of aneuploidy

Yitzhak Pilpel, Weizmann Institute of Science, Israel

17:30-18:00 Coffee Break
18:00-18:20 Population genomics of a protoploid yeast species: Saccharomyces kluyveri

Joseph Schacherer, University of Strasbourg, France

18:20-18:50 Chimeric protein interactions generate novel evolutionary phenotypes and shape the pattern of genome evolution in yeast hybrids
Daniela Delneri, University of Manchester, United Kingdom
18:50-19:20 A genetic incompatibility in DNA mismatch repair strains of baker's yeast: consequences for adaptive evolution 

Eric Alani, Cornell University, USA

19:30-21:30 Dinner
  After Dinner Drinks (Roof Top Lounge)



DAY 3: Friday 19 October 2012
Time Topic

Session 3:

Chair: Phil Hieter, University of British Columbia, Canada
09:00-09:30 The genomic landscape of antagonistic pleiotropy in yeast

Jianzhi Zhang, University of Michigan, USA 

9:30 - 10:00 Speed kills - why fast gene regulation is not always better

Kevin Verstrepen, University of Leuven, Belgium  

10:00 - 10:30 Tetraploidy and genome evolution

David Pellman, Harvard University, USA 

10:30-11:00 Coffee Break kindly sponsored by Lessafre International
11:00-11:30 Ploidy change as a stress response

Judy Berman, University of Minnesota, USA 

11:30-12:00 Massive amplification of chromosomal segments during experimental evolution of unfit yeast genomes

Bernard Dujon, Institut Pasteur, CNRS and University P & M Curie, France

12:00-13:00 Lunch
13:00-14:10 Session 4:

Chair: Justin Fay, University of Washington, USA  

13:00-13:20 Fitness costs of excessive protein synthesis in yeast

Katarzyna Tomala, Jagiellonian University, Poland

13:20-13:40 Divergence of mitotic mechanisms within the fission yeast clade

Snezhana Oliferenko, Temasek Life Sciences Laboratory (TLL), Singapore

13:40-14:10 The glass half full: the consequences of heterozygosis

Stephen Oliver, University of Cambridge, United Kingdom 

14:20-15:30 Special Discussion Session I

Chairs: Peter Philippsen & Marko Kaksonen

Mating-type switching in Kluyveromyces lactis

Stefan Astrom, Stockholm University, Sweden

Mitochondrial-Nuclear Epistasis Contributes to Phenotypic Variation in Wild Yeasts

Heather Fiumera, Binghamton University, USA

Behavioural networks reveal evolution of complexity in wild yeast

Chris Knight, University of Manchester, UK

A surprising level of asymmetry in yeast single-cell division rates explains variation in population-level growth rates

Aaron New, VIB Systems Biology Lab, KU Leuven Belgium

Evolutionary cell biology of clathrin-mediated endocytosis

Marko Kaksonen, EMBL, Germany

Evolution of budding yeast cells to multinucleated fungal hyphae growing in an ecological niche low in glucose and rich in neutral fat

Peter Philippsen, Biozentrum, University of Basel, Switzerland
14:20-15:45 Special Discussion Session II 

Chair: Justin Fay

Lineage tracking in yeast using random molecular barcodes

Sasha Levy, Stanford University, USA

Mapping quantitative trait loci across the species-wide genetic diversity of S. cerevisiae

Sebastian Treusch, Lewis Sigler Institute, Princeton University, USA

Sequencing reveals the dynamics of adaptation in asexual populations

Gregory Lang, Princeton University, USA

Predicting loci of functional evolution within ancestral genes

Victor Hanson-Smith, University of Calilfornia San Francisco, USA

Reversion of a genetic code alteration generates genetic and phenotypic diversity in Candida albicans

Ana Bezerra, CESAM - University of Aveiro, Portugal

Evolving a circadian oscillator in budding yeast

Gregg Wildenberg, Harvard University, USA

Rare genetic variants underlie common morphologies and growth traits in a wild yeast population

Jeremy Roop, University of California Berkeley, USA
  Free Time



DAY 4 Saturday 20 October 2012
Time Topic
09:00-12:40 Session 5:

Chair: Jef Boeke, John Hopkins University, USA

09:00-09:30 Possibilities and limitations of non-conventional yeasts to understand evolution of disease potential

Teun Boekhout, CBS-KNAW Fungal Biodiversity Centre, The Netherlands 

09:30-10:00 Expanding the synthetic capabilities of yeast

Virginia Cornish, Columbia University, USA 

10:00-10:30 Domestication and diversification of Saccharomyces cerevisiae

Justin Fay, University of Washington, USA 

10:30-11:00 Coffee Break
11:00-11:30 Aneuploidy as a mechanism for a multicellular phenotypic toggle

Aimee Dudley, Institute for Systems Biology, USA  

11:30-11:50 Rapid evolutionary compensation following gene loss in yeast

Csaba Pal, Biological Research Center, Hungary

11:50-12:10 Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity

Himanshu Sinha, Tata Institute of Fundamental Research, India

12:10-12:40 Particle Genetics: treating every cell as unique

Gael Yvert, École Normale Supérieur de Lyon, France  

12:40-14:00 Lunch

Helix B (poster numbers 76 - 116)

16:00-19:20 Session 6:

Chair: Stephen Oliver, University of Cambridge, United Kingdom

16:00-16:30 Purifying selection in yeast

Vassiliki Koufopanou, Imperial College London, United Kingdom  

16:30-17:00 Modular functionalization of yeast centrosomes in sexual processes and the organization of microtubules during mating

Michael Knop, Zentrum für Molekulare Biologie in Heidelberg (ZMBH), Germany  

17:00-17:30 Hsp90 regulates non-genetic variation in response to environmental stress

Jun-Yi Leu, Institute of Molecular Biology, Academia Sinica, Taiwan 

17:30-18:00 Coffee Break
18:00-18:20 A prion induced by inter-kingdom chemical communication regulates growth and survival strategies
Daniel Jarosz, Whitehead Institute, USA
18:20-18:50 Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators

Phil Hieter, University of British Columbia, Canada  

19:00-00:00 Dinner & Party kindly sponsored by Singer Instruments



DAY 5 Sunday 21 October 2012